data-cut-off-date,web-posting-date,aesi-category,aesi,pfizer-events,moderna-events,cov-azc-events,janssen-events,Novavax-events,unspecified-events,total-events,pfizer-rate,moderna-rate,cov-azc-rate,Janssen-rate,total-rate
2021-05-14,2021-05-21,Auto-immune diseases,Guillain-Barré Syndrome,7,0,6,,,0,13,N/A,N/A,N/A,,N/A
2021-05-14,2021-05-21,Auto-immune diseases,Thrombocytopenia (low blood platelets),6,1,15,,,0,22,N/A,N/A,N/A,,N/A
2021-05-14,2021-05-21,Auto-immune diseases,Subtotal n (%),13,1,21,,,0,35,N/A,N/A,N/A,,N/A
2021-05-14,2021-05-21,Cardiovascular system,Cardiac arrest,3,5,1,,,0,9,N/A,N/A,N/A,,N/A
2021-05-14,2021-05-21,Cardiovascular system,Cardiac failure,1,0,0,,,0,1,N/A,N/A,N/A,,N/A
2021-05-14,2021-05-21,Cardiovascular system,Microangiopathy,0,0,0,,,0,0,N/A,N/A,N/A,,N/A
2021-05-14,2021-05-21,Cardiovascular system,Myocardial infarction (heart attack),8,4,3,,,0,15,N/A,N/A,N/A,,N/A
2021-05-14,2021-05-21,Cardiovascular system,Myocarditis (heart inflammation),12,2,1,,,0,15,N/A,N/A,N/A,,N/A
2021-05-14,2021-05-21,Cardiovascular system,Stress cardiomyopathy,0,0,0,,,0,0,N/A,N/A,N/A,,N/A
2021-05-14,2021-05-21,Cardiovascular system,Subtotal n (%),24,11,5,,,0,40,N/A,N/A,N/A,,N/A
2021-05-14,2021-05-21,Circulatory system,Cerebral venous (sinus) thrombosis,0,0,4,,,0,4,N/A,N/A,N/A,,N/A
2021-05-14,2021-05-21,Circulatory system,Cerebral thrombosis,0,1,2,,,0,3,N/A,N/A,N/A,,N/A
2021-05-14,2021-05-21,Circulatory system,Cutaneous vasculitis,1,0,0,,,0,1,N/A,N/A,N/A,,N/A
2021-05-14,2021-05-21,Circulatory system,Deep vein thrombosis,13,6,17,,,0,36,N/A,N/A,N/A,,N/A
2021-05-14,2021-05-21,Circulatory system,Embolism,0,0,2,,,0,2,N/A,N/A,N/A,,N/A
2021-05-14,2021-05-21,Circulatory system,Haemorrhage (bleeding),3,2,1,,,0,6,N/A,N/A,N/A,,N/A
2021-05-14,2021-05-21,Circulatory system,Pulmonary embolism,31,9,35,,,0,75,N/A,N/A,N/A,,N/A
2021-05-14,2021-05-21,Circulatory system,Thrombosis (blood clot),14,1,21,,,3,39,N/A,N/A,N/A,,N/A
2021-05-14,2021-05-21,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),0,0,22,,,0,22,N/A,N/A,N/A,,N/A
2021-05-14,2021-05-21,Circulatory system,Subtotal n (%),62,19,104,,,3,188,N/A,N/A,N/A,,N/A
2021-05-14,2021-05-21,Hepato-gastrointestinal and renal system,Acute kidney injury,7,1,0,,,0,8,N/A,N/A,N/A,,N/A
2021-05-14,2021-05-21,Hepato-gastrointestinal and renal system,Liver injury,1,0,0,,,0,1,N/A,N/A,N/A,,N/A
2021-05-14,2021-05-21,Hepato-gastrointestinal and renal system,Subtotal n (%),8,1,0,,,0,9,N/A,N/A,N/A,,N/A
2021-05-14,2021-05-21,Nerves and central nervous system,Bell's Palsy/Facial Paralysis,93,27,11,,,0,131,N/A,N/A,N/A,,N/A
2021-05-14,2021-05-21,Nerves and central nervous system,Cerebrovascular accident (stroke),28,4,13,,,1,46,N/A,N/A,N/A,,N/A
2021-05-14,2021-05-21,Nerves and central nervous system,Generalized convulsion (seizure),0,0,0,,,0,0,N/A,N/A,N/A,,N/A
2021-05-14,2021-05-21,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),4,2,0,,,0,6,N/A,N/A,N/A,,N/A
2021-05-14,2021-05-21,Nerves and central nervous system,Subtotal n (%),125,33,24,,,1,183,N/A,N/A,N/A,,N/A
2021-05-14,2021-05-21,Other system,Anaphylaxis,53,9,0,,,0,62,N/A,N/A,N/A,,N/A
2021-05-14,2021-05-21,Other system,COVID-19*,55,0,1,,,0,56,N/A,N/A,N/A,,N/A
2021-05-14,2021-05-21,Other system,Subtotal n (%),108,9,1,,,0,118,N/A,N/A,N/A,,N/A
2021-05-14,2021-05-21,Pregnancy outcomes,Fetal growth restriction,3,0,0,,,0,3,N/A,N/A,N/A,,N/A
2021-05-14,2021-05-21,Pregnancy outcomes,Spontaneous abortion,3,0,0,,,0,3,N/A,N/A,N/A,,N/A
2021-05-14,2021-05-21,Pregnancy outcomes,Subtotal n (%),6,0,0,,,0,6,N/A,N/A,N/A,,N/A
2021-05-14,2021-05-21,Respiratory system,Acute respiratory distress syndrome,1,0,0,,,0,1,N/A,N/A,N/A,,N/A
2021-05-14,2021-05-21,Respiratory system,Subtotal n (%),1,0,0,,,0,1,N/A,N/A,N/A,,N/A
2021-05-14,2021-05-21,"Skin and mucous membrane, bone and joints system",Chilblains,3,0,0,,,0,3,N/A,N/A,N/A,,N/A
2021-05-14,2021-05-21,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),2,1,1,,,0,4,N/A,N/A,N/A,,N/A
2021-05-14,2021-05-21,"Skin and mucous membrane, bone and joints system",Subtotal n (%),5,1,1,,,0,7,N/A,N/A,N/A,,N/A
2021-05-14,2021-05-21,All AESI categories ,TOTAL,352,75,156,,,4,587,N/A,N/A,N/A,,N/A
2021-05-21,2021-05-28,Auto-immune diseases,Guillain-Barré Syndrome,7,0,8,,,0,15,N/A,N/A,N/A,,N/A
2021-05-21,2021-05-28,Auto-immune diseases,Thrombocytopenia (low blood platelets),6,1,12,,,0,19,N/A,N/A,N/A,,N/A
2021-05-21,2021-05-28,Auto-immune diseases,Subtotal n (%),13,1,20,,,0,34,N/A,N/A,N/A,,N/A
2021-05-21,2021-05-28,Cardiovascular system,Cardiac arrest,4,5,1,,,0,10,N/A,N/A,N/A,,N/A
2021-05-21,2021-05-28,Cardiovascular system,Cardiac failure,3,0,0,,,0,3,N/A,N/A,N/A,,N/A
2021-05-21,2021-05-28,Cardiovascular system,Microangiopathy,0,0,0,,,0,0,N/A,N/A,N/A,,N/A
2021-05-21,2021-05-28,Cardiovascular system,Myocardial infarction (heart attack),11,5,3,,,0,18,N/A,N/A,N/A,,N/A
2021-05-21,2021-05-28,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),18,3,2,,,0,23,N/A,N/A,N/A,,N/A
2021-05-21,2021-05-28,Cardiovascular system,Stress cardiomyopathy,0,0,0,,,0,0,N/A,N/A,N/A,,N/A
2021-05-21,2021-05-28,Cardiovascular system,Subtotal n (%),36,13,6,,,0,54,N/A,N/A,N/A,,N/A
2021-05-21,2021-05-28,Circulatory system,Cerebral venous (sinus) thrombosis,1,0,4,,,0,5,N/A,N/A,N/A,,N/A
2021-05-21,2021-05-28,Circulatory system,Cerebral thrombosis ,0,1,2,,,0,3,N/A,N/A,N/A,,N/A
2021-05-21,2021-05-28,Circulatory system,Cutaneous vasculitis,1,0,0,,,0,1,N/A,N/A,N/A,,N/A
2021-05-21,2021-05-28,Circulatory system,Deep vein thrombosis,17,7,19,,,0,43,N/A,N/A,N/A,,N/A
2021-05-21,2021-05-28,Circulatory system,Embolism,1,0,3,,,0,4,N/A,N/A,N/A,,N/A
2021-05-21,2021-05-28,Circulatory system,Haemorrhage (bleeding),3,3,1,,,0,7,N/A,N/A,N/A,,N/A
2021-05-21,2021-05-28,Circulatory system,Pulmonary embolism,34,13,40,,,0,86,N/A,N/A,N/A,,N/A
2021-05-21,2021-05-28,Circulatory system,Thrombosis (blood clot),19,1,23,,,3,46,N/A,N/A,N/A,,N/A
2021-05-21,2021-05-28,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),0,0,33,,,0,33,N/A,N/A,N/A,,N/A
2021-05-21,2021-05-28,Circulatory system,Subtotal n (%),76,25,125,,,3,228,N/A,N/A,N/A,,N/A
2021-05-21,2021-05-28,Hepato-gastrointestinal and renal system,Acute kidney injury,7,2,0,,,0,8,N/A,N/A,N/A,,N/A
2021-05-21,2021-05-28,Hepato-gastrointestinal and renal system,Liver injury,1,0,0,,,0,1,N/A,N/A,N/A,,N/A
2021-05-21,2021-05-28,Hepato-gastrointestinal and renal system,Subtotal n (%),8,2,0,,,0,9,N/A,N/A,N/A,,N/A
2021-05-21,2021-05-28,Nerves and central nervous system,Bell's Palsy/Facial paralysis,105,27,15,,,0,147,N/A,N/A,N/A,,N/A
2021-05-21,2021-05-28,Nerves and central nervous system,Cerebrovascular accident (stroke),29,4,13,,,1,47,N/A,N/A,N/A,,N/A
2021-05-21,2021-05-28,Nerves and central nervous system,Generalized convulsion (seizure),0,0,0,,,0,0,N/A,N/A,N/A,,N/A
2021-05-21,2021-05-28,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),4,2,0,,,0,6,N/A,N/A,N/A,,N/A
2021-05-21,2021-05-28,Nerves and central nervous system,Subtotal n (%),138,33,28,,,1,200,N/A,N/A,N/A,,N/A
2021-05-21,2021-05-28,Other system,Anaphylaxis,59,10,0,,,0,69,N/A,N/A,N/A,,N/A
2021-05-21,2021-05-28,Other system,COVID-19*,55,0,1,,,0,56,N/A,N/A,N/A,,N/A
2021-05-21,2021-05-28,Other system,Subtotal n (%),114,10,1,,,0,125,N/A,N/A,N/A,,N/A
2021-05-21,2021-05-28,Pregnancy outcomes,Fetal growth restriction,3,0,0,,,0,3,N/A,N/A,N/A,,N/A
2021-05-21,2021-05-28,Pregnancy outcomes,Spontaneous abortion,7,1,0,,,0,8,N/A,N/A,N/A,,N/A
2021-05-21,2021-05-28,Pregnancy outcomes,Subtotal n (%),10,1,0,,,0,11,N/A,N/A,N/A,,N/A
2021-05-21,2021-05-28,Respiratory system,Acute respiratory distress syndrome,1,0,0,,,0,1,N/A,N/A,N/A,,N/A
2021-05-21,2021-05-28,Respiratory system,Subtotal n (%),1,0,0,,,0,1,N/A,N/A,N/A,,N/A
2021-05-21,2021-05-28,"Skin and mucous membrane, bone and joints system",Chilblains,3,0,0,,,0,3,N/A,N/A,N/A,,N/A
2021-05-21,2021-05-28,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),2,2,1,,,0,5,N/A,N/A,N/A,,N/A
2021-05-21,2021-05-28,"Skin and mucous membrane, bone and joints system",Subtotal n (%),5,2,1,,,0,8,N/A,N/A,N/A,,N/A
2021-05-21,2021-05-28,All AESI categories ,TOTAL,401,87,181,,,4,673,N/A,N/A,N/A,,N/A
2021-05-28,2021-06-04,Auto-immune diseases,Guillain-Barré Syndrome,3,0,8,,,0,11,N/A,N/A,N/A,,N/A
2021-05-28,2021-06-04,Auto-immune diseases,Thrombocytopenia (low blood platelets),10,1,19,,,0,30,N/A,N/A,N/A,,N/A
2021-05-28,2021-06-04,Auto-immune diseases,Subtotal n (%),13,1,27,,,0,41,N/A,N/A,N/A,,N/A
2021-05-28,2021-06-04,Cardiovascular system,Cardiac arrest,4,6,1,,,0,11,N/A,N/A,N/A,,N/A
2021-05-28,2021-06-04,Cardiovascular system,Cardiac failure,4,0,1,,,0,5,N/A,N/A,N/A,,N/A
2021-05-28,2021-06-04,Cardiovascular system,Myocardial infarction (heart attack),14,7,3,,,0,24,N/A,N/A,N/A,,N/A
2021-05-28,2021-06-04,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),19,4,2,,,0,25,N/A,N/A,N/A,,N/A
2021-05-28,2021-06-04,Cardiovascular system,Subtotal n (%),41,17,7,,,0,65,N/A,N/A,N/A,,N/A
2021-05-28,2021-06-04,Circulatory system,Cerebral venous (sinus) thrombosis,1,0,6,,,0,7,N/A,N/A,N/A,,N/A
2021-05-28,2021-06-04,Circulatory system,Cerebral thrombosis ,0,1,2,,,0,3,N/A,N/A,N/A,,N/A
2021-05-28,2021-06-04,Circulatory system,Cutaneous vasculitis,2,1,0,,,0,3,N/A,N/A,N/A,,N/A
2021-05-28,2021-06-04,Circulatory system,Deep vein thrombosis,20,8,25,,,0,53,N/A,N/A,N/A,,N/A
2021-05-28,2021-06-04,Circulatory system,Embolism,1,0,3,,,0,4,N/A,N/A,N/A,,N/A
2021-05-28,2021-06-04,Circulatory system,Haemorrhage (bleeding),4,5,2,,,0,11,N/A,N/A,N/A,,N/A
2021-05-28,2021-06-04,Circulatory system,Pulmonary embolism,39,15,48,,,0,102,N/A,N/A,N/A,,N/A
2021-05-28,2021-06-04,Circulatory system,Thrombosis (blood clot),20,1,24,,,3,48,N/A,N/A,N/A,,N/A
2021-05-28,2021-06-04,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),1,1,42,,,0,44,N/A,N/A,N/A,,N/A
2021-05-28,2021-06-04,Circulatory system,Subtotal n (%),88,32,152,,,3,275,N/A,N/A,N/A,,N/A
2021-05-28,2021-06-04,Hepato-gastrointestinal and renal system,Acute kidney injury,9,3,0,,,0,12,N/A,N/A,N/A,,N/A
2021-05-28,2021-06-04,Hepato-gastrointestinal and renal system,Liver injury,1,0,0,,,0,1,N/A,N/A,N/A,,N/A
2021-05-28,2021-06-04,Hepato-gastrointestinal and renal system,Subtotal n (%),10,3,0,,,0,13,N/A,N/A,N/A,,N/A
2021-05-28,2021-06-04,Nerves and central nervous system,Bell's Palsy/Facial paralysis,111,31,19,,,0,161,N/A,N/A,N/A,,N/A
2021-05-28,2021-06-04,Nerves and central nervous system,Cerebrovascular accident (stroke),32,4,19,,,2,57,N/A,N/A,N/A,,N/A
2021-05-28,2021-06-04,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),4,2,0,,,0,6,N/A,N/A,N/A,,N/A
2021-05-28,2021-06-04,Nerves and central nervous system,Subtotal n (%),147,37,38,,,2,224,N/A,N/A,N/A,,N/A
2021-05-28,2021-06-04,Other system,Anaphylaxis,57,12,0,,,0,69,N/A,N/A,N/A,,N/A
2021-05-28,2021-06-04,Other system,COVID-19*,60,1,2,,,0,63,N/A,N/A,N/A,,N/A
2021-05-28,2021-06-04,Other system,Subtotal n (%),117,13,2,,,0,132,N/A,N/A,N/A,,N/A
2021-05-28,2021-06-04,Pregnancy outcomes,Fetal growth restriction,2,0,0,,,0,2,N/A,N/A,N/A,,N/A
2021-05-28,2021-06-04,Pregnancy outcomes,Spontaneous abortion,7,2,0,,,0,9,N/A,N/A,N/A,,N/A
2021-05-28,2021-06-04,Pregnancy outcomes,Subtotal n (%),9,2,0,,,0,11,N/A,N/A,N/A,,N/A
2021-05-28,2021-06-04,Respiratory system,Acute respiratory distress syndrome,1,0,0,,,0,1,N/A,N/A,N/A,,N/A
2021-05-28,2021-06-04,Respiratory system,Subtotal n (%),1,0,0,,,0,1,N/A,N/A,N/A,,N/A
2021-05-28,2021-06-04,"Skin and mucous membrane, bone and joints system",Chilblains,3,0,0,,,0,3,N/A,N/A,N/A,,N/A
2021-05-28,2021-06-04,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),4,2,1,,,0,7,N/A,N/A,N/A,,N/A
2021-05-28,2021-06-04,"Skin and mucous membrane, bone and joints system",Subtotal n (%),7,2,1,,,0,10,N/A,N/A,N/A,,N/A
2021-05-28,2021-06-04,All AESI categories ,TOTAL,433,107,227,,,5,772,N/A,N/A,N/A,,N/A
2021-06-04,2021-06-11,Auto-immune diseases,Guillain-Barré Syndrome,4,0,9,,,0,13,N/A,N/A,N/A,,N/A
2021-06-04,2021-06-11,Auto-immune diseases,Thrombocytopenia (low blood platelets),10,1,23,,,0,34,N/A,N/A,N/A,,N/A
2021-06-04,2021-06-11,Auto-immune diseases,Subtotal n (%),14,1,32,,,0,47,N/A,N/A,N/A,,N/A
2021-06-04,2021-06-11,Cardiovascular system,Cardiac arrest,4,6,3,,,0,13,N/A,N/A,N/A,,N/A
2021-06-04,2021-06-11,Cardiovascular system,Cardiac failure,5,0,1,,,0,6,N/A,N/A,N/A,,N/A
2021-06-04,2021-06-11,Cardiovascular system,Myocardial infarction (heart attack),14,7,5,,,0,26,N/A,N/A,N/A,,N/A
2021-06-04,2021-06-11,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),25,6,3,,,1,35,N/A,N/A,N/A,,N/A
2021-06-04,2021-06-11,Cardiovascular system,Subtotal n (%),48,19,12,,,1,80,N/A,N/A,N/A,,N/A
2021-06-04,2021-06-11,Circulatory system,Cerebral venous (sinus) thrombosis,1,0,8,,,0,9,N/A,N/A,N/A,,N/A
2021-06-04,2021-06-11,Circulatory system,Cerebral thrombosis ,0,1,2,,,0,3,N/A,N/A,N/A,,N/A
2021-06-04,2021-06-11,Circulatory system,Cutaneous vasculitis,2,1,0,,,0,3,N/A,N/A,N/A,,N/A
2021-06-04,2021-06-11,Circulatory system,Deep vein thrombosis,20,8,27,,,0,55,N/A,N/A,N/A,,N/A
2021-06-04,2021-06-11,Circulatory system,Embolism,1,0,3,,,0,4,N/A,N/A,N/A,,N/A
2021-06-04,2021-06-11,Circulatory system,Haemorrhage (bleeding),4,6,3,,,0,13,N/A,N/A,N/A,,N/A
2021-06-04,2021-06-11,Circulatory system,Pulmonary embolism,45,17,59,,,1,122,N/A,N/A,N/A,,N/A
2021-06-04,2021-06-11,Circulatory system,Thrombosis (blood clot),29,1,37,,,4,71,N/A,N/A,N/A,,N/A
2021-06-04,2021-06-11,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),3,1,46,,,0,50,N/A,N/A,N/A,,N/A
2021-06-04,2021-06-11,Circulatory system,Subtotal n (%),105,35,185,,,5,330,N/A,N/A,N/A,,N/A
2021-06-04,2021-06-11,Hepato-gastrointestinal and renal system,Acute kidney injury,9,3,0,,,0,12,N/A,N/A,N/A,,N/A
2021-06-04,2021-06-11,Hepato-gastrointestinal and renal system,Liver injury,1,0,0,,,0,1,N/A,N/A,N/A,,N/A
2021-06-04,2021-06-11,Hepato-gastrointestinal and renal system,Subtotal n (%),10,3,0,,,0,13,N/A,N/A,N/A,,N/A
2021-06-04,2021-06-11,Nerves and central nervous system,Bell's Palsy/Facial paralysis,117,35,24,,,0,176,N/A,N/A,N/A,,N/A
2021-06-04,2021-06-11,Nerves and central nervous system,Cerebrovascular accident (stroke),35,4,19,,,2,60,N/A,N/A,N/A,,N/A
2021-06-04,2021-06-11,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),4,2,1,,,0,7,N/A,N/A,N/A,,N/A
2021-06-04,2021-06-11,Nerves and central nervous system,Subtotal n (%),156,41,44,,,2,243,N/A,N/A,N/A,,N/A
2021-06-04,2021-06-11,Other system,Anaphylaxis,60,12,0,,,0,72,N/A,N/A,N/A,,N/A
2021-06-04,2021-06-11,Other system,COVID-19*,66,1,2,,,0,69,N/A,N/A,N/A,,N/A
2021-06-04,2021-06-11,Other system,Subtotal n (%),126,13,2,,,0,141,N/A,N/A,N/A,,N/A
2021-06-04,2021-06-11,Pregnancy outcomes,Fetal growth restriction,3,0,0,,,0,3,N/A,N/A,N/A,,N/A
2021-06-04,2021-06-11,Pregnancy outcomes,Spontaneous abortion,9,2,0,,,0,11,N/A,N/A,N/A,,N/A
2021-06-04,2021-06-11,Pregnancy outcomes,Subtotal n (%),12,2,0,,,0,14,N/A,N/A,N/A,,N/A
2021-06-04,2021-06-11,Respiratory system,Acute respiratory distress syndrome,1,0,0,,,0,1,N/A,N/A,N/A,,N/A
2021-06-04,2021-06-11,Respiratory system,Subtotal n (%),1,0,0,,,0,1,N/A,N/A,N/A,,N/A
2021-06-04,2021-06-11,"Skin and mucous membrane, bone and joints system",Chilblains,3,0,0,,,0,3,N/A,N/A,N/A,,N/A
2021-06-04,2021-06-11,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),4,2,1,,,0,7,N/A,N/A,N/A,,N/A
2021-06-04,2021-06-11,"Skin and mucous membrane, bone and joints system",Subtotal n (%),7,2,1,,,0,10,N/A,N/A,N/A,,N/A
2021-06-04,2021-06-11,All AESI categories ,TOTAL,479,116,276,,,8,879,N/A,N/A,N/A,,N/A
2021-06-11,2021-06-18,Auto-immune diseases,Guillain-Barré Syndrome,8,2,13,,,0,23,0.04,0.04,0.52,,0.08
2021-06-11,2021-06-18,Auto-immune diseases,Thrombocytopenia (low blood platelets),10,2,29,,,0,41,0.05,0.04,1.17,,0.14
2021-06-11,2021-06-18,Auto-immune diseases,Subtotal n (%),18,4,42,,,0,64,0.08,0.07,1.70,,0.22
2021-06-11,2021-06-18,Cardiovascular system,Cardiac arrest,4,7,5,,,0,16,0.02,0.13,0.20,,0.05
2021-06-11,2021-06-18,Cardiovascular system,Cardiac failure,7,0,2,,,0,9,0.03,0.00,0.08,,0.03
2021-06-11,2021-06-18,Cardiovascular system,Myocardial infarction (heart attack),16,7,5,,,0,28,0.08,0.13,0.20,,0.10
2021-06-11,2021-06-18,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),40,8,4,,,1,53,0.19,0.15,0.16,,0.18
2021-06-11,2021-06-18,Cardiovascular system,Subtotal n (%),67,22,16,,,1,106,0.31,0.40,0.65,,0.36
2021-06-11,2021-06-18,Circulatory system,Cerebral venous (sinus) thrombosis,2,0,9,,,0,11,0.01,0.00,0.36,,0.04
2021-06-11,2021-06-18,Circulatory system,Cerebral thrombosis ,1,1,2,,,0,4,0.00,0.02,0.08,,0.01
2021-06-11,2021-06-18,Circulatory system,Cutaneous vasculitis,2,2,0,,,1,5,0.01,0.04,0.00,,0.02
2021-06-11,2021-06-18,Circulatory system,Deep vein thrombosis,31,12,32,,,1,76,0.15,0.22,1.29,,0.26
2021-06-11,2021-06-18,Circulatory system,Embolism,1,0,4,,,0,5,0.00,0.00,0.16,,0.02
2021-06-11,2021-06-18,Circulatory system,Haemorrhage (bleeding),5,6,4,,,0,15,0.02,0.11,0.16,,0.05
2021-06-11,2021-06-18,Circulatory system,Pulmonary embolism,51,18,69,,,1,139,0.24,0.33,2.79,,0.47
2021-06-11,2021-06-18,Circulatory system,Thrombosis (blood clot),36,1,51,,,4,92,0.17,0.02,2.06,,0.31
2021-06-11,2021-06-18,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),3,0,52,,,0,55,0.01,0.00,2.10,,0.19
2021-06-11,2021-06-18,Circulatory system,Subtotal n (%),132,40,223,,,7,402,0.62,0.73,9.00,,1.37
2021-06-11,2021-06-18,Hepato-gastrointestinal and renal system,Acute kidney injury,10,3,1,,,0,14,0.05,0.05,0.04,,0.05
2021-06-11,2021-06-18,Hepato-gastrointestinal and renal system,Liver injury,2,1,0,,,0,3,0.01,0.02,0.00,,0.01
2021-06-11,2021-06-18,Hepato-gastrointestinal and renal system,Subtotal n (%),12,4,1,,,0,17,0.06,0.07,0.04,,0.06
2021-06-11,2021-06-18,Nerves and central nervous system,Bell's Palsy,91,20,14,,,12,137,0.43,0.37,0.57,,0.47
2021-06-11,2021-06-18,Nerves and central nervous system,Cerebrovascular accident (stroke),37,4,21,,,2,64,0.17,0.07,0.85,,0.22
2021-06-11,2021-06-18,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),5,2,2,,,0,9,0.02,0.04,0.08,,0.03
2021-06-11,2021-06-18,Nerves and central nervous system,Subtotal n (%),133,26,37,,,14,210,0.62,0.48,1.49,,0.72
2021-06-11,2021-06-18,Other system,Anaphylaxis,63,13,0,,,0,76,0.30,0.24,0.00,,0.26
2021-06-11,2021-06-18,Other system,COVID-19*,83,1,2,,,0,86,0.39,0.02,0.08,,0.29
2021-06-11,2021-06-18,Other system,Subtotal n (%),146,14,2,,,0,162,0.69,0.26,0.08,,0.55
2021-06-11,2021-06-18,Pregnancy outcomes,Fetal growth restriction,3,0,0,,,0,3,0.01,0.00,0.00,,0.01
2021-06-11,2021-06-18,Pregnancy outcomes,Spontaneous abortion,10,2,0,,,0,12,0.05,0.04,0.00,,0.04
2021-06-11,2021-06-18,Pregnancy outcomes,Subtotal n (%),13,2,0,,,0,15,0.06,0.04,0.00,,0.05
2021-06-11,2021-06-18,Respiratory system,Acute respiratory distress syndrome,1,0,0,,,0,1,0.00,0.00,0.00,,0.00
2021-06-11,2021-06-18,Respiratory system,Subtotal n (%),1,0,0,,,0,1,0.00,0.00,0.00,,0.00
2021-06-11,2021-06-18,"Skin and mucous membrane, bone and joints system",Chilblains,4,0,0,,,0,4,0.02,0.00,0.00,,0.01
2021-06-11,2021-06-18,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),4,2,1,,,0,7,0.02,0.04,0.04,,0.02
2021-06-11,2021-06-18,"Skin and mucous membrane, bone and joints system",Subtotal n (%),8,2,1,,,0,11,0.04,0.04,0.04,,0.04
2021-06-11,2021-06-18,All AESI categories ,TOTAL,530,114,322,,,22,988,2.49,2.08,13.00,,3.38
2021-06-18,2021-06-25,Auto-immune diseases,Guillain-Barré Syndrome,10,2,16,,,0,28,0.04,0.03,0.62,,0.09
2021-06-18,2021-06-25,Auto-immune diseases,Thrombocytopenia (low blood platelets),11,2,34,,,0,47,0.05,0.03,1.31,,0.15
2021-06-18,2021-06-25,Auto-immune diseases,Subtotal n (%),21,4,50,,,0,75,0.09,0.07,1.93,,0.23
2021-06-18,2021-06-25,Cardiovascular system,Cardiac arrest,5,7,5,,,0,17,0.02,0.12,0.19,,0.05
2021-06-18,2021-06-25,Cardiovascular system,Cardiac failure,7,0,2,,,0,9,0.03,0.00,0.08,,0.03
2021-06-18,2021-06-25,Cardiovascular system,Myocardial infarction (heart attack),18,7,5,,,0,30,0.08,0.12,0.19,,0.09
2021-06-18,2021-06-25,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),50,10,5,,,0,65,0.21,0.17,0.19,,0.20
2021-06-18,2021-06-25,Cardiovascular system,Subtotal n (%),80,24,17,,,0,121,0.34,0.40,0.65,,0.37
2021-06-18,2021-06-25,Circulatory system,Cerebral venous (sinus) thrombosis,2,0,10,,,0,12,0.01,0.00,0.39,,0.04
2021-06-18,2021-06-25,Circulatory system,Cerebral thrombosis ,1,1,2,,,0,4,0.00,0.02,0.08,,0.01
2021-06-18,2021-06-25,Circulatory system,Cutaneous vasculitis,2,1,0,,,0,3,0.01,0.02,0.00,,0.01
2021-06-18,2021-06-25,Circulatory system,Deep vein thrombosis,35,13,35,,,1,84,0.15,0.22,1.35,,0.26
2021-06-18,2021-06-25,Circulatory system,Embolism,2,0,5,,,0,7,0.01,0.00,0.19,,0.02
2021-06-18,2021-06-25,Circulatory system,Haemorrhage (bleeding),7,6,4,,,0,17,0.03,0.10,0.15,,0.05
2021-06-18,2021-06-25,Circulatory system,Pulmonary embolism,59,23,73,,,1,156,0.25,0.38,2.81,,0.48
2021-06-18,2021-06-25,Circulatory system,Thrombosis (blood clot),38,4,59,,,4,105,0.16,0.07,2.27,,0.32
2021-06-18,2021-06-25,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),3,1,54,,,0,58,0.01,0.02,2.08,,0.18
2021-06-18,2021-06-25,Circulatory system,Subtotal n (%),149,49,242,,,6,446,0.63,0.82,9.32,,1.38
2021-06-18,2021-06-25,Hepato-gastrointestinal and renal system,Acute kidney injury,11,3,1,,,0,15,0.05,0.05,0.04,,0.05
2021-06-18,2021-06-25,Hepato-gastrointestinal and renal system,Liver injury,2,1,0,,,0,3,0.01,0.02,0.00,,0.01
2021-06-18,2021-06-25,Hepato-gastrointestinal and renal system,Subtotal n (%),13,4,1,,,0,18,0.05,0.07,0.04,,0.06
2021-06-18,2021-06-25,Nerves and central nervous system,Bell's Palsy,110,32,22,,,0,164,0.46,0.53,0.85,,0.51
2021-06-18,2021-06-25,Nerves and central nervous system,Cerebrovascular accident (stroke),42,6,21,,,2,71,0.18,0.10,0.81,,0.22
2021-06-18,2021-06-25,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),6,2,2,,,0,10,0.03,0.03,0.08,,0.03
2021-06-18,2021-06-25,Nerves and central nervous system,Subtotal n (%),158,40,45,,,2,245,0.66,0.67,1.73,,0.76
2021-06-18,2021-06-25,Other system,Anaphylaxis,70,13,0,,,0,83,0.29,0.22,0.00,,0.26
2021-06-18,2021-06-25,Other system,COVID-19*,83,1,2,,,0,86,0.35,0.02,0.08,,0.27
2021-06-18,2021-06-25,Other system,Subtotal n (%),153,14,2,,,0,169,0.64,0.23,0.08,,0.52
2021-06-18,2021-06-25,Pregnancy outcomes,Fetal growth restriction,3,0,0,,,0,3,0.01,0.00,0.00,,0.01
2021-06-18,2021-06-25,Pregnancy outcomes,Spontaneous abortion,11,2,0,,,0,13,0.05,0.03,0.00,,0.04
2021-06-18,2021-06-25,Pregnancy outcomes,Subtotal n (%),14,2,0,,,0,16,0.06,0.03,0.00,,0.05
2021-06-18,2021-06-25,Respiratory system,Acute respiratory distress syndrome,1,0,0,,,0,1,0.00,0.00,0.00,,0.00
2021-06-18,2021-06-25,Respiratory system,Subtotal n (%),1,0,0,,,0,1,0.00,0.00,0.00,,0.00
2021-06-18,2021-06-25,"Skin and mucous membrane, bone and joints system",Chilblains,5,0,0,,,0,5,0.02,0.00,0.00,,0.02
2021-06-18,2021-06-25,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),5,3,1,,,0,9,0.02,0.05,0.04,,0.03
2021-06-18,2021-06-25,"Skin and mucous membrane, bone and joints system",Subtotal n (%),10,3,1,,,0,14,0.04,0.05,0.04,,0.04
2021-06-18,2021-06-25,All AESI categories ,TOTAL,599,140,358,,,8,1105,2.52,2.34,13.79,,3.41
2021-06-25,2021-07-05,Auto-immune diseases,Guillain-Barré Syndrome,11,3,17,,,1,32,0.05,0.05,0.65,,0.10
2021-06-25,2021-07-05,Auto-immune diseases,Thrombocytopenia (low blood platelets),12,3,33,,,0,48,0.05,0.05,1.27,,0.15
2021-06-25,2021-07-05,Auto-immune diseases,Subtotal n (%),23,6,50,,,1,80,0.10,0.10,1.93,,0.25
2021-06-25,2021-07-05,Cardiovascular system,Cardiac arrest,6,7,5,,,0,18,0.03,0.12,0.19,,0.06
2021-06-25,2021-07-05,Cardiovascular system,Cardiac failure,8,0,2,,,0,10,0.03,0.00,0.08,,0.03
2021-06-25,2021-07-05,Cardiovascular system,Myocardial infarction (heart attack),19,7,4,,,0,30,0.08,0.12,0.15,,0.09
2021-06-25,2021-07-05,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),64,18,7,,,1,90,0.27,0.30,0.27,,0.28
2021-06-25,2021-07-05,Cardiovascular system,Subtotal n (%),97,32,18,,,1,148,0.41,0.53,0.69,,0.46
2021-06-25,2021-07-05,Circulatory system,Cerebral venous (sinus) thrombosis,2,0,10,,,0,12,0.01,0.00,0.39,,0.04
2021-06-25,2021-07-05,Circulatory system,Cerebral thrombosis ,1,1,2,,,0,4,0.00,0.02,0.08,,0.01
2021-06-25,2021-07-05,Circulatory system,Cutaneous vasculitis,2,3,0,,,0,5,0.01,0.05,0.00,,0.02
2021-06-25,2021-07-05,Circulatory system,Deep vein thrombosis,37,14,39,,,1,91,0.16,0.23,1.50,,0.28
2021-06-25,2021-07-05,Circulatory system,Embolism,2,1,5,,,0,8,0.01,0.02,0.19,,0.02
2021-06-25,2021-07-05,Circulatory system,Haemorrhage (bleeding),7,6,4,,,0,17,0.03,0.10,0.15,,0.05
2021-06-25,2021-07-05,Circulatory system,Pulmonary embolism,65,24,79,,,1,169,0.27,0.40,3.04,,0.52
2021-06-25,2021-07-05,Circulatory system,Thrombosis (blood clot),41,4,59,,,4,108,0.17,0.07,2.27,,0.33
2021-06-25,2021-07-05,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),3,1,55,,,0,59,0.01,0.02,2.12,,0.18
2021-06-25,2021-07-05,Circulatory system,Subtotal n (%),160,54,253,,,6,473,0.67,0.90,9.74,,1.46
2021-06-25,2021-07-05,Hepato-gastrointestinal and renal system,Acute kidney injury,12,3,1,,,0,16,0.05,0.05,0.04,,0.05
2021-06-25,2021-07-05,Hepato-gastrointestinal and renal system,Liver injury,3,1,0,,,0,4,0.01,0.02,0.00,,0.01
2021-06-25,2021-07-05,Hepato-gastrointestinal and renal system,Subtotal n (%),15,4,1,,,0,20,0.06,0.07,0.04,,0.06
2021-06-25,2021-07-05,Nerves and central nervous system,Bell's Palsy,145,41,28,,,1,215,0.61,0.68,1.08,,0.66
2021-06-25,2021-07-05,Nerves and central nervous system,Cerebrovascular accident (stroke),45,7,22,,,2,76,0.19,0.12,0.85,,0.23
2021-06-25,2021-07-05,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),8,2,3,,,0,13,0.03,0.03,0.12,,0.04
2021-06-25,2021-07-05,Nerves and central nervous system,Subtotal n (%),198,50,53,,,3,304,0.83,0.84,2.04,,0.94
2021-06-25,2021-07-05,Other system,Anaphylaxis,72,14,1,,,0,87,0.30,0.23,0.04,,0.27
2021-06-25,2021-07-05,Other system,COVID-19*,84,1,2,,,0,87,0.35,0.02,0.08,,0.27
2021-06-25,2021-07-05,Other system,Subtotal n (%),156,15,3,,,0,174,0.66,0.25,0.12,,0.54
2021-06-25,2021-07-05,Pregnancy outcomes,Fetal growth restriction,4,0,0,,,0,4,0.02,0.00,0.00,,0.01
2021-06-25,2021-07-05,Pregnancy outcomes,Spontaneous abortion,12,3,0,,,0,15,0.05,0.05,0.00,,0.05
2021-06-25,2021-07-05,Pregnancy outcomes,Subtotal n (%),16,3,0,,,0,19,0.07,0.05,0.00,,0.06
2021-06-25,2021-07-05,Respiratory system,Acute respiratory distress syndrome,1,0,0,,,0,1,0.00,0.00,0.00,,0.00
2021-06-25,2021-07-05,Respiratory system,Subtotal n (%),1,0,0,,,0,1,0.00,0.00,0.00,,0.00
2021-06-25,2021-07-05,"Skin and mucous membrane, bone and joints system",Chilblains,5,0,0,,,0,5,0.02,0.00,0.00,,0.02
2021-06-25,2021-07-05,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),6,3,1,,,0,10,0.03,0.05,0.04,,0.03
2021-06-25,2021-07-05,"Skin and mucous membrane, bone and joints system",Subtotal n (%),11,3,1,,,0,15,0.05,0.05,0.04,,0.05
2021-06-25,2021-07-05,All AESI categories ,TOTAL,677,167,379,,,11,1234,2.85,2.79,14.59,,3.81
2021-07-02,2021-07-09,Auto-immune diseases,Guillain-Barré Syndrome,12,4,20,,,1,37,0.05,0.05,0.75,,0.10
2021-07-02,2021-07-09,Auto-immune diseases,Thrombocytopenia (low blood platelets),12,4,33,,,1,50,0.05,0.05,1.23,,0.14
2021-07-02,2021-07-09,Auto-immune diseases,Subtotal n (%),24,8,53,,,2,87,0.09,0.10,1.97,,0.24
2021-07-02,2021-07-09,Cardiovascular system,Cardiac arrest,6,8,5,,,0,19,0.02,0.10,0.19,,0.05
2021-07-02,2021-07-09,Cardiovascular system,Cardiac failure,8,1,2,,,0,11,0.03,0.01,0.07,,0.03
2021-07-02,2021-07-09,Cardiovascular system,Myocardial infarction (heart attack),21,7,5,,,1,34,0.08,0.09,0.19,,0.10
2021-07-02,2021-07-09,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),70,26,8,,,1,105,0.28,0.34,0.30,,0.29
2021-07-02,2021-07-09,Cardiovascular system,Subtotal n (%),105,42,20,,,2,169,0.41,0.55,0.75,,0.47
2021-07-02,2021-07-09,Circulatory system,Cerebral venous (sinus) thrombosis,2,0,10,,,0,12,0.01,0.00,0.37,,0.03
2021-07-02,2021-07-09,Circulatory system,Cerebral thrombosis ,2,1,2,,,0,5,0.01,0.01,0.07,,0.01
2021-07-02,2021-07-09,Circulatory system,Cutaneous vasculitis,2,3,0,,,0,5,0.01,0.04,0.00,,0.01
2021-07-02,2021-07-09,Circulatory system,Deep vein thrombosis,41,18,41,,,1,101,0.16,0.24,1.53,,0.28
2021-07-02,2021-07-09,Circulatory system,Embolism,2,1,5,,,0,8,0.01,0.01,0.19,,0.02
2021-07-02,2021-07-09,Circulatory system,Haemorrhage (bleeding),10,6,5,,,0,21,0.04,0.08,0.19,,0.06
2021-07-02,2021-07-09,Circulatory system,Pulmonary embolism,67,26,81,,,1,175,0.26,0.34,3.02,,0.49
2021-07-02,2021-07-09,Circulatory system,Thrombosis (blood clot),46,4,62,,,4,116,0.18,0.05,2.31,,0.32
2021-07-02,2021-07-09,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),3,1,55,,,0,59,0.01,0.01,2.05,,0.16
2021-07-02,2021-07-09,Circulatory system,Subtotal n (%),175,60,261,,,6,502,0.69,0.79,9.73,,1.40
2021-07-02,2021-07-09,Hepato-gastrointestinal and renal system,Acute kidney injury,11,3,1,,,0,15,0.04,0.04,0.04,,0.04
2021-07-02,2021-07-09,Hepato-gastrointestinal and renal system,Liver injury,3,1,0,,,0,4,0.01,0.01,0.00,,0.01
2021-07-02,2021-07-09,Hepato-gastrointestinal and renal system,Subtotal n (%),14,4,1,,,0,19,0.06,0.05,0.04,,0.05
2021-07-02,2021-07-09,Nerves and central nervous system,Bell's Palsy,158,46,31,,,1,236,0.62,0.60,1.16,,0.66
2021-07-02,2021-07-09,Nerves and central nervous system,Cerebrovascular accident (stroke),48,9,23,,,2,82,0.19,0.12,0.86,,0.23
2021-07-02,2021-07-09,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),8,3,3,,,0,14,0.03,0.04,0.11,,0.04
2021-07-02,2021-07-09,Nerves and central nervous system,Subtotal n (%),214,58,57,,,3,332,0.84,0.76,2.12,,0.93
2021-07-02,2021-07-09,Other system,Anaphylaxis,79,15,0,,,0,94,0.31,0.20,0.00,,0.26
2021-07-02,2021-07-09,Other system,COVID-19*,85,1,2,,,0,88,0.33,0.01,0.07,,0.25
2021-07-02,2021-07-09,Other system,Subtotal n (%),164,16,2,,,0,182,0.64,0.21,0.07,,0.51
2021-07-02,2021-07-09,Pregnancy outcomes,Fetal growth restriction,4,0,0,,,0,4,0.02,0.00,0.00,,0.01
2021-07-02,2021-07-09,Pregnancy outcomes,Spontaneous abortion,12,4,0,,,0,16,0.05,0.05,0.00,,0.04
2021-07-02,2021-07-09,Pregnancy outcomes,Subtotal n (%),16,4,0,,,0,20,0.06,0.05,0.00,,0.06
2021-07-02,2021-07-09,Respiratory system,Acute respiratory distress syndrome,1,0,0,,,0,1,0.00,0.00,0.00,,0.00
2021-07-02,2021-07-09,Respiratory system,Subtotal n (%),1,0,0,,,0,1,0.00,0.00,0.00,,0.00
2021-07-02,2021-07-09,"Skin and mucous membrane, bone and joints system",Chilblains,5,0,0,,,0,5,0.02,0.00,0.00,,0.01
2021-07-02,2021-07-09,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),6,3,1,,,0,10,0.02,0.04,0.04,,0.03
2021-07-02,2021-07-09,"Skin and mucous membrane, bone and joints system",Subtotal n (%),11,3,1,,,0,15,0.04,0.04,0.04,,0.04
2021-07-02,2021-07-09,All AESI categories ,TOTAL,724,195,395,,,13,1327,2.85,2.56,14.72,,3.71
2021-07-09,2021-07-16,Auto-immune diseases,Guillain-Barré Syndrome,14,4,25,,,0,43,0.05,0.04,0.92,,0.11
2021-07-09,2021-07-16,Auto-immune diseases,Thrombocytopenia (low blood platelets),12,4,33,,,1,50,0.04,0.04,1.21,,0.13
2021-07-09,2021-07-16,Auto-immune diseases,Subtotal n (%),26,8,58,,,1,93,0.09,0.09,2.14,,0.24
2021-07-09,2021-07-16,Cardiovascular system,Cardiac arrest,6,8,5,,,0,19,0.02,0.09,0.18,,0.05
2021-07-09,2021-07-16,Cardiovascular system,Cardiac failure,9,2,2,,,0,13,0.03,0.02,0.07,,0.03
2021-07-09,2021-07-16,Cardiovascular system,Myocardial infarction (heart attack),25,8,7,,,1,41,0.09,0.09,0.26,,0.10
2021-07-09,2021-07-16,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),111,40,11,,,1,163,0.40,0.44,0.40,,0.41
2021-07-09,2021-07-16,Cardiovascular system,Subtotal n (%),151,58,25,,,2,236,0.55,0.64,0.92,,0.60
2021-07-09,2021-07-16,Circulatory system,Cerebral venous (sinus) thrombosis,3,0,11,,,0,14,0.01,0.00,0.40,,0.04
2021-07-09,2021-07-16,Circulatory system,Cerebral thrombosis ,2,1,2,,,0,5,0.01,0.01,0.07,,0.01
2021-07-09,2021-07-16,Circulatory system,Cutaneous vasculitis,3,3,0,,,0,6,0.01,0.03,0.00,,0.02
2021-07-09,2021-07-16,Circulatory system,Deep vein thrombosis,49,20,42,,,0,111,0.18,0.22,1.55,,0.28
2021-07-09,2021-07-16,Circulatory system,Embolism,2,1,5,,,0,8,0.01,0.01,0.18,,0.02
2021-07-09,2021-07-16,Circulatory system,Haemorrhage (bleeding),4,6,6,,,0,16,0.01,0.07,0.22,,0.04
2021-07-09,2021-07-16,Circulatory system,Pulmonary embolism,76,28,84,,,1,189,0.27,0.31,3.09,,0.48
2021-07-09,2021-07-16,Circulatory system,Thrombosis (blood clot),49,8,64,,,2,123,0.18,0.09,2.36,,0.31
2021-07-09,2021-07-16,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),3,1,55,,,0,59,0.01,0.01,2.02,,0.15
2021-07-09,2021-07-16,Circulatory system,Subtotal n (%),191,68,269,,,3,531,0.69,0.75,9.90,,1.35
2021-07-09,2021-07-16,Hepato-gastrointestinal and renal system,Acute kidney injury,13,3,1,,,0,17,0.05,0.03,0.04,,0.04
2021-07-09,2021-07-16,Hepato-gastrointestinal and renal system,Liver injury,5,1,1,,,0,7,0.02,0.01,0.04,,0.02
2021-07-09,2021-07-16,Hepato-gastrointestinal and renal system,Subtotal n (%),18,4,2,,,0,24,0.07,0.04,0.07,,0.06
2021-07-09,2021-07-16,Nerves and central nervous system,Bell's Palsy/facial paralysis,173,51,35,,,1,260,0.63,0.56,1.29,,0.66
2021-07-09,2021-07-16,Nerves and central nervous system,Cerebrovascular accident (stroke),52,11,25,,,2,90,0.19,0.12,0.92,,0.23
2021-07-09,2021-07-16,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),9,3,4,,,0,16,0.03,0.03,0.15,,0.04
2021-07-09,2021-07-16,Nerves and central nervous system,Subtotal n (%),234,65,64,,,3,366,0.85,0.72,2.36,,0.93
2021-07-09,2021-07-16,Other system,Anaphylaxis,90,18,0,,,0,108,0.33,0.20,0.00,,0.27
2021-07-09,2021-07-16,Other system,COVID-19*,85,7,6,,,0,98,0.31,0.08,0.22,,0.25
2021-07-09,2021-07-16,Other system,Subtotal n (%),175,25,6,,,0,206,0.63,0.28,0.22,,0.52
2021-07-09,2021-07-16,Pregnancy outcomes,Fetal growth restriction,4,0,0,,,0,4,0.01,0.00,0.00,,0.01
2021-07-09,2021-07-16,Pregnancy outcomes,Spontaneous abortion,14,4,0,,,0,18,0.05,0.04,0.00,,0.05
2021-07-09,2021-07-16,Pregnancy outcomes,Subtotal n (%),18,4,0,,,0,22,0.07,0.04,0.00,,0.06
2021-07-09,2021-07-16,Respiratory system,Acute respiratory distress syndrome,1,0,0,,,0,1,0.00,0.00,0.00,,0.00
2021-07-09,2021-07-16,Respiratory system,Subtotal n (%),1,0,0,,,0,1,0.00,0.00,0.00,,0.00
2021-07-09,2021-07-16,"Skin and mucous membrane, bone and joints system",Chilblains,5,0,0,,,0,5,0.02,0.00,0.00,,0.01
2021-07-09,2021-07-16,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),7,3,1,,,0,11,0.03,0.03,0.04,,0.03
2021-07-09,2021-07-16,"Skin and mucous membrane, bone and joints system",Subtotal n (%),12,3,1,,,0,16,0.04,0.03,0.04,,0.04
2021-07-09,2021-07-16,All AESI categories,TOTAL,826,235,425,,,9,1495,2.99,2.60,15.64,,3.79
2021-07-16,2021-07-23,Auto-immune diseases,Guillain-Barré Syndrome,18,5,25,,,0,48,0.06,0.05,0.91,,0.11
2021-07-16,2021-07-23,Auto-immune diseases,Thrombocytopenia (low blood platelets),15,5,40,,,1,61,0.05,0.05,1.45,,0.14
2021-07-16,2021-07-23,Auto-immune diseases,Subtotal n (%),33,10,65,,,1,109,0.11,0.10,2.36,,0.25
2021-07-16,2021-07-23,Cardiovascular system,Cardiac arrest,7,8,5,,,0,20,0.02,0.08,0.18,,0.05
2021-07-16,2021-07-23,Cardiovascular system,Cardiac failure,9,2,2,,,0,13,0.03,0.02,0.07,,0.03
2021-07-16,2021-07-23,Cardiovascular system,Myocardial infarction (heart attack),30,11,10,,,1,52,0.10,0.11,0.36,,0.12
2021-07-16,2021-07-23,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),132,66,12,,,1,211,0.45,0.63,0.44,,0.49
2021-07-16,2021-07-23,Cardiovascular system,Subtotal n (%),178,87,29,,,2,296,0.60,0.83,1.05,,0.69
2021-07-16,2021-07-23,Circulatory system,Cerebral venous (sinus) thrombosis,3,0,12,,,0,15,0.01,0.00,0.44,,0.04
2021-07-16,2021-07-23,Circulatory system,Cerebral thrombosis ,2,1,2,,,0,5,0.01,0.01,0.07,,0.01
2021-07-16,2021-07-23,Circulatory system,Cutaneous vasculitis,4,3,0,,,0,7,0.01,0.03,0.00,,0.02
2021-07-16,2021-07-23,Circulatory system,Deep vein thrombosis,63,22,49,,,0,134,0.21,0.21,1.78,,0.31
2021-07-16,2021-07-23,Circulatory system,Embolism,2,1,5,,,0,8,0.01,0.01,0.18,,0.02
2021-07-16,2021-07-23,Circulatory system,Haemorrhage (bleeding),12,6,8,,,0,26,0.04,0.06,0.29,,0.06
2021-07-16,2021-07-23,Circulatory system,Pulmonary embolism,84,30,87,,,1,202,0.28,0.29,3.16,,0.47
2021-07-16,2021-07-23,Circulatory system,Thrombosis (blood clot),53,8,63,,,2,126,0.18,0.08,2.29,,0.29
2021-07-16,2021-07-23,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),9,2,56,,,0,67,0.03,0.02,2.03,,0.16
2021-07-16,2021-07-23,Circulatory system,Subtotal n (%),232,73,282,,,3,590,0.78,0.70,10.24,,1.38
2021-07-16,2021-07-23,Hepato-gastrointestinal and renal system,Acute kidney injury,14,4,1,,,0,19,0.05,0.04,0.04,,0.04
2021-07-16,2021-07-23,Hepato-gastrointestinal and renal system,Liver injury,6,1,2,,,0,9,0.02,0.01,0.07,,0.02
2021-07-16,2021-07-23,Hepato-gastrointestinal and renal system,Subtotal n (%),20,5,3,,,0,28,0.07,0.05,0.11,,0.07
2021-07-16,2021-07-23,Nerves and central nervous system,Bell's Palsy/facial paralysis,185,60,35,,,1,281,0.63,0.57,1.27,,0.66
2021-07-16,2021-07-23,Nerves and central nervous system,Cerebrovascular accident (stroke),59,12,29,,,2,102,0.20,0.11,1.05,,0.24
2021-07-16,2021-07-23,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),11,3,4,,,0,18,0.04,0.03,0.15,,0.04
2021-07-16,2021-07-23,Nerves and central nervous system,Subtotal n (%),255,75,68,,,3,401,0.86,0.72,2.47,,0.94
2021-07-16,2021-07-23,Other system,Anaphylaxis,95,19,0,,,0,114,0.32,0.18,0.00,,0.27
2021-07-16,2021-07-23,Other system,COVID-19*,89,2,0,,,1,92,0.30,0.02,0.00,,0.22
2021-07-16,2021-07-23,Other system,Subtotal n (%),184,21,0,,,1,206,0.62,0.20,0.00,,0.48
2021-07-16,2021-07-23,Pregnancy outcomes,Fetal growth restriction,4,0,0,,,0,4,0.01,0.00,0.00,,0.01
2021-07-16,2021-07-23,Pregnancy outcomes,Spontaneous abortion,16,4,0,,,0,20,0.05,0.04,0.00,,0.02
2021-07-16,2021-07-23,Pregnancy outcomes,Subtotal n (%),20,4,0,,,0,24,0.07,0.04,0.00,,0.06
2021-07-16,2021-07-23,Respiratory system,Acute respiratory distress syndrome,2,1,0,,,0,2,0.01,0.01,0.00,,0.00
2021-07-16,2021-07-23,Respiratory system,Subtotal n (%),2,1,0,,,0,2,0.01,0.01,0.00,,0.00
2021-07-16,2021-07-23,"Skin and mucous membrane, bone and joints system",Chilblains,6,0,0,,,0,6,0.02,0.00,0.00,,0.01
2021-07-16,2021-07-23,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),9,3,1,,,0,13,0.03,0.03,0.04,,0.03
2021-07-16,2021-07-23,"Skin and mucous membrane, bone and joints system",Subtotal n (%),15,3,1,,,0,19,0.05,0.03,0.04,,0.04
2021-07-16,2021-07-23,All AESI categories,TOTAL,939,279,448,,,10,1675,3.18,2.67,16.27,,3.91
2021-07-23,2021-07-30,Auto-immune diseases,Guillain-Barré Syndrome,20,8,25,,,0,53,0.06,0.07,0.91,,0.12
2021-07-23,2021-07-30,Auto-immune diseases,Thrombocytopenia (low blood platelets),15,5,45,,,2,67,0.05,0.04,1.63,,0.15
2021-07-23,2021-07-30,Auto-immune diseases,Subtotal n (%),35,13,70,,,2,120,0.11,0.11,2.53,,0.26
2021-07-23,2021-07-30,Cardiovascular system,Cardiac arrest,8,8,5,,,0,21,0.03,0.07,0.18,,0.05
2021-07-23,2021-07-30,Cardiovascular system,Cardiac failure,9,2,3,,,0,14,0.03,0.02,0.11,,0.03
2021-07-23,2021-07-30,Cardiovascular system,Myocardial infarction (heart attack),32,13,8,,,1,54,0.10,0.11,0.29,,0.12
2021-07-23,2021-07-30,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),145,71,12,,,2,230,0.46,0.62,0.43,,0.51
2021-07-23,2021-07-30,Cardiovascular system,Subtotal n (%),194,94,28,,,3,319,0.62,0.82,1.01,,0.70
2021-07-23,2021-07-30,Circulatory system,Cerebral venous (sinus) thrombosis,3,0,14,,,0,17,0.01,0.00,0.51,,0.04
2021-07-23,2021-07-30,Circulatory system,Cerebral thrombosis ,2,1,2,,,0,5,0.01,0.01,0.07,,0.01
2021-07-23,2021-07-30,Circulatory system,Cutaneous vasculitis,4,3,0,,,0,7,0.01,0.03,0.00,,0.02
2021-07-23,2021-07-30,Circulatory system,Deep vein thrombosis,65,22,49,,,0,136,0.21,0.19,1.77,,0.30
2021-07-23,2021-07-30,Circulatory system,Embolism,2,1,6,,,0,9,0.01,0.01,0.22,,0.02
2021-07-23,2021-07-30,Circulatory system,Haemorrhage (bleeding),16,7,8,,,0,31,0.05,0.06,0.29,,0.07
2021-07-23,2021-07-30,Circulatory system,Pulmonary embolism,88,32,91,,,1,212,0.28,0.28,3.30,,0.47
2021-07-23,2021-07-30,Circulatory system,Thrombosis (blood clot),58,8,69,,,2,137,0.19,0.07,2.50,,0.30
2021-07-23,2021-07-30,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),9,2,56,,,0,67,0.03,0.02,2.03,,0.15
2021-07-23,2021-07-30,Circulatory system,Subtotal n (%),247,76,295,,,3,621,0.79,0.66,10.68,,1.36
2021-07-23,2021-07-30,Hepato-gastrointestinal and renal system,Acute kidney injury,14,4,1,,,0,19,0.04,0.03,0.04,,0.04
2021-07-23,2021-07-30,Hepato-gastrointestinal and renal system,Liver injury,6,2,2,,,0,10,0.02,0.02,0.07,,0.02
2021-07-23,2021-07-30,Hepato-gastrointestinal and renal system,Subtotal n (%),20,6,3,,,0,29,0.06,0.05,0.11,,0.06
2021-07-23,2021-07-30,Nerves and central nervous system,Bell's Palsy/facial paralysis,191,63,36,,,1,291,0.61,0.55,1.30,,0.64
2021-07-23,2021-07-30,Nerves and central nervous system,Cerebrovascular accident (stroke),58,15,29,,,2,104,0.19,0.13,1.05,,0.23
2021-07-23,2021-07-30,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),11,3,4,,,0,18,0.04,0.03,0.14,,0.04
2021-07-23,2021-07-30,Nerves and central nervous system,Subtotal n (%),260,81,69,,,3,413,0.83,0.70,2.50,,0.91
2021-07-23,2021-07-30,Other system,Anaphylaxis,113,24,0,,,0,137,0.36,0.21,0.00,,0.30
2021-07-23,2021-07-30,Other system,COVID-19*,90,1,1,,,0,92,0.29,0.01,0.04,,0.20
2021-07-23,2021-07-30,Other system,Subtotal n (%),203,25,1,,,0,229,0.65,0.22,0.04,,0.50
2021-07-23,2021-07-30,Pregnancy outcomes,Fetal growth restriction,4,0,0,,,0,4,0.01,0.00,0.00,,0.01
2021-07-23,2021-07-30,Pregnancy outcomes,Spontaneous abortion,16,4,0,,,0,20,0.05,0.03,0.00,,0.04
2021-07-23,2021-07-30,Pregnancy outcomes,Subtotal n (%),20,4,0,,,0,24,0.06,0.03,0.00,,0.05
2021-07-23,2021-07-30,Respiratory system,Acute respiratory distress syndrome,2,1,0,,,0,2,0.01,0.01,0.00,,0.00
2021-07-23,2021-07-30,Respiratory system,Subtotal n (%),2,1,0,,,0,2,0.01,0.01,0.00,,0.00
2021-07-23,2021-07-30,"Skin and mucous membrane, bone and joints system",Chilblains,6,1,0,,,0,7,0.02,0.01,0.00,,0.02
2021-07-23,2021-07-30,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),9,3,1,,,0,13,0.03,0.03,0.04,,0.03
2021-07-23,2021-07-30,"Skin and mucous membrane, bone and joints system",Subtotal n (%),15,4,1,,,0,20,0.05,0.03,0.04,,0.04
2021-07-23,2021-07-30,All AESI categories,TOTAL,996,304,467,,,11,1777,3.19,2.64,16.91,,3.91
2021-07-30,2021-08-06,Auto-immune diseases,Guillain-Barré Syndrome,21,8,26,,,0,55,0.06,0.07,0.94,,0.11
2021-07-30,2021-08-06,Auto-immune diseases,Thrombocytopenia (low blood platelets),17,7,40,,,2,66,0.05,0.06,1.45,,0.14
2021-07-30,2021-08-06,Auto-immune diseases,Subtotal n (%),38,15,66,,,2,121,0.11,0.12,2.38,,0.25
2021-07-30,2021-08-06,Cardiovascular system,Cardiac arrest,8,8,5,,,0,21,0.02,0.07,0.18,,0.04
2021-07-30,2021-08-06,Cardiovascular system,Cardiac failure,9,2,3,,,1,15,0.03,0.02,0.11,,0.03
2021-07-30,2021-08-06,Cardiovascular system,Myocardial infarction (heart attack),33,14,8,,,1,56,0.10,0.12,0.29,,0.12
2021-07-30,2021-08-06,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),194,145,13,,,2,354,0.59,1.20,0.47,,0.74
2021-07-30,2021-08-06,Cardiovascular system,Subtotal n (%),244,169,29,,,4,446,0.74,1.40,1.05,,0.93
2021-07-30,2021-08-06,Circulatory system,Cerebral venous (sinus) thrombosis,2,1,12,,,0,15,0.01,0.01,0.43,,0.03
2021-07-30,2021-08-06,Circulatory system,Cerebral thrombosis,2,1,2,,,0,5,0.01,0.01,0.07,,0.01
2021-07-30,2021-08-06,Circulatory system,Cutaneous vasculitis,5,3,0,,,0,8,0.02,0.02,0.00,,0.02
2021-07-30,2021-08-06,Circulatory system,Deep vein thrombosis,77,24,49,,,0,150,0.23,0.20,1.77,,0.31
2021-07-30,2021-08-06,Circulatory system,Embolism,2,1,5,,,0,8,0.01,0.01,0.18,,0.02
2021-07-30,2021-08-06,Circulatory system,Haemorrhage (bleeding),17,7,8,,,0,32,0.05,0.06,0.29,,0.07
2021-07-30,2021-08-06,Circulatory system,Pulmonary embolism,95,35,90,,,1,221,0.29,0.29,3.25,,0.46
2021-07-30,2021-08-06,Circulatory system,Thrombosis (blood clot),64,13,70,,,2,149,0.19,0.11,2.53,,0.31
2021-07-30,2021-08-06,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),13,3,56,,,0,72,0.04,0.02,2.02,,0.15
2021-07-30,2021-08-06,Circulatory system,Subtotal n (%),277,88,292,,,3,660,0.84,0.73,10.55,,1.38
2021-07-30,2021-08-06,Hepato-gastrointestinal and renal system,Acute kidney injury,14,7,2,,,0,23,0.04,0.06,0.07,,0.05
2021-07-30,2021-08-06,Hepato-gastrointestinal and renal system,Liver injury,7,2,3,,,0,12,0.02,0.02,0.11,,0.03
2021-07-30,2021-08-06,Hepato-gastrointestinal and renal system,Subtotal n (%),21,9,5,,,0,35,0.06,0.07,0.18,,0.07
2021-07-30,2021-08-06,Nerves and central nervous system,Bell's Palsy/facial paralysis,206,67,37,,,1,311,0.62,0.56,1.34,,0.65
2021-07-30,2021-08-06,Nerves and central nervous system,Cerebrovascular accident (stroke),62,20,29,,,2,113,0.19,0.17,1.05,,0.24
2021-07-30,2021-08-06,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),11,3,4,,,0,18,0.03,0.02,0.14,,0.04
2021-07-30,2021-08-06,Nerves and central nervous system,Subtotal n (%),279,90,70,,,3,442,0.84,0.75,2.53,,0.92
2021-07-30,2021-08-06,Other system,Anaphylaxis,123,27,0,,,0,150,0.37,0.22,0.00,,0.31
2021-07-30,2021-08-06,Other system,COVID-19*,91,2,1,,,1,95,0.28,0.02,0.04,,0.20
2021-07-30,2021-08-06,Other system,Subtotal n (%),214,29,1,,,1,245,0.65,0.24,0.04,,0.51
2021-07-30,2021-08-06,Pregnancy outcomes,Fetal growth restriction,5,0,0,,,0,5,0.02,0.00,0.00,,0.01
2021-07-30,2021-08-06,Pregnancy outcomes,Spontaneous abortion,17,5,0,,,0,22,0.05,0.04,0.00,,0.05
2021-07-30,2021-08-06,Pregnancy outcomes,Subtotal n (%),22,5,0,,,0,27,0.07,0.04,0.00,,0.06
2021-07-30,2021-08-06,Respiratory system,Acute respiratory distress syndrome,2,1,0,,,0,3,0.01,0.01,0.00,,0.01
2021-07-30,2021-08-06,Respiratory system,Subtotal n (%),2,1,0,,,0,3,0.01,0.01,0.00,,0.01
2021-07-30,2021-08-06,"Skin and mucous membrane, bone and joints system",Chilblains,6,1,0,,,0,7,0.02,0.01,0.00,,0.01
2021-07-30,2021-08-06,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),9,6,1,,,0,16,0.03,0.05,0.04,,0.03
2021-07-30,2021-08-06,"Skin and mucous membrane, bone and joints system",Subtotal n (%),15,7,1,,,0,23,0.05,0.06,0.04,,0.05
2021-07-30,2021-08-06,All AESI categories,TOTAL,1112,413,464,,,13,2002,3.36,3.43,16.77,,4.18
2021-08-06,2021-08-13,Auto-immune diseases,Guillain-Barré Syndrome,22,9,27,,,0,58,0.06,0.07,0.97,,0.12
2021-08-06,2021-08-13,Auto-immune diseases,Thrombocytopenia (low blood platelets),17,7,40,,,3,67,0.05,0.06,1.44,,0.14
2021-08-06,2021-08-13,Auto-immune diseases,Subtotal n (%),39,16,67,,,3,125,0.11,0.13,2.42,,0.25
2021-08-06,2021-08-13,Cardiovascular system,Cardiac arrest,8,8,5,,,0,21,0.02,0.06,0.18,,0.04
2021-08-06,2021-08-13,Cardiovascular system,Cardiac failure,9,3,3,,,1,16,0.03,0.02,0.11,,0.03
2021-08-06,2021-08-13,Cardiovascular system,Myocardial infarction (heart attack),33,14,8,,,1,56,0.10,0.11,0.29,,0.11
2021-08-06,2021-08-13,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),223,184,14,,,2,423,0.65,1.49,0.50,,0.85
2021-08-06,2021-08-13,Cardiovascular system,Subtotal n (%),273,209,30,,,4,516,0.79,1.69,1.08,,1.04
2021-08-06,2021-08-13,Circulatory system,Cerebral venous (sinus) thrombosis,2,1,11,,,0,14,0.01,0.01,0.40,,0.03
2021-08-06,2021-08-13,Circulatory system,Cerebral thrombosis,2,1,2,,,0,5,0.01,0.01,0.07,,0.01
2021-08-06,2021-08-13,Circulatory system,Cutaneous vasculitis,7,3,0,,,0,10,0.02,0.02,0.00,,0.02
2021-08-06,2021-08-13,Circulatory system,Deep vein thrombosis,81,26,50,,,0,157,0.24,0.21,1.80,,0.32
2021-08-06,2021-08-13,Circulatory system,Embolism,2,1,5,,,0,8,0.01,0.01,0.18,,0.02
2021-08-06,2021-08-13,Circulatory system,Haemorrhage (bleeding),18,7,8,,,0,33,0.05,0.06,0.29,,0.07
2021-08-06,2021-08-13,Circulatory system,Pulmonary embolism,101,35,91,,,1,228,0.29,0.28,3.28,,0.46
2021-08-06,2021-08-13,Circulatory system,Thrombosis (blood clot),68,14,70,,,2,154,0.20,0.11,2.52,,0.31
2021-08-06,2021-08-13,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),13,3,56,,,0,72,0.04,0.02,2.02,,0.15
2021-08-06,2021-08-13,Circulatory system,Subtotal n (%),294,91,293,,,3,681,0.85,0.74,10.57,,1.37
2021-08-06,2021-08-13,Hepato-gastrointestinal and renal system,Acute kidney injury,14,7,2,,,0,23,0.04,0.06,0.07,,0.05
2021-08-06,2021-08-13,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),2,0,0,,,0,2,0.01,0.00,0.00,,0.00
2021-08-06,2021-08-13,Hepato-gastrointestinal and renal system,Liver injury,8,2,3,,,0,13,0.02,0.02,0.11,,0.03
2021-08-06,2021-08-13,Hepato-gastrointestinal and renal system,Subtotal n (%),24,9,5,,,0,38,0.07,0.07,0.18,,0.08
2021-08-06,2021-08-13,Nerves and central nervous system,Bell's Palsy/facial paralysis,218,76,38,,,1,333,0.63,0.62,1.37,,0.67
2021-08-06,2021-08-13,Nerves and central nervous system,Cerebrovascular accident (stroke),65,20,30,,,2,117,0.19,0.16,1.08,,0.24
2021-08-06,2021-08-13,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),11,3,4,,,0,18,0.03,0.02,0.14,,0.04
2021-08-06,2021-08-13,Nerves and central nervous system,Subtotal n (%),294,99,72,,,3,468,0.85,0.80,2.60,,0.94
2021-08-06,2021-08-13,Other system,Anaphylaxis,126,29,0,,,0,155,0.37,0.23,0.00,,0.31
2021-08-06,2021-08-13,Other system,COVID-19*,92,2,1,,,1,96,0.27,0.02,0.04,,0.19
2021-08-06,2021-08-13,Other system,Subtotal n (%),218,31,1,,,1,251,0.63,0.25,0.04,,0.51
2021-08-06,2021-08-13,Pregnancy outcomes,Fetal growth restriction,5,0,0,,,0,5,0.01,0.00,0.00,,0.01
2021-08-06,2021-08-13,Pregnancy outcomes,Spontaneous abortion,21,5,0,,,0,26,0.06,0.04,0.00,,0.05
2021-08-06,2021-08-13,Pregnancy outcomes,Subtotal n (%),26,5,0,,,0,31,0.08,0.04,0.00,,0.06
2021-08-06,2021-08-13,Respiratory system,Acute respiratory distress syndrome,2,1,0,,,0,3,0.01,0.01,0.00,,0.01
2021-08-06,2021-08-13,Respiratory system,Subtotal n (%),2,1,0,,,0,3,0.01,0.01,0.00,,0.01
2021-08-06,2021-08-13,"Skin and mucous membrane, bone and joints system",Chilblains,6,2,0,,,0,8,0.02,0.02,0.00,,0.02
2021-08-06,2021-08-13,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),10,6,1,,,0,17,0.03,0.05,0.04,,0.03
2021-08-06,2021-08-13,"Skin and mucous membrane, bone and joints system",Subtotal n (%),16,8,1,,,0,25,0.05,0.06,0.04,,0.05
2021-08-06,2021-08-13,All AESI categories,TOTAL,1186,469,469,,,14,2138,3.44,3.80,16.92,,4.31
2021-08-13,2021-08-20,Auto-immune diseases,Guillain-Barré Syndrome,24,11,29,,,0,64,0.07,0.09,1.04,,0.13
2021-08-13,2021-08-20,Auto-immune diseases,Thrombocytopenia (low blood platelets),17,8,40,,,3,68,0.05,0.06,1.44,,0.13
2021-08-13,2021-08-20,Auto-immune diseases,Subtotal n (%),41,19,69,,,3,132,0.12,0.15,2.48,,0.26
2021-08-13,2021-08-20,Cardiovascular system,Cardiac arrest,9,8,5,,,0,22,0.03,0.06,0.18,,0.04
2021-08-13,2021-08-20,Cardiovascular system,Cardiac failure,10,3,3,,,1,17,0.03,0.02,0.11,,0.03
2021-08-13,2021-08-20,Cardiovascular system,Myocardial infarction (heart attack),38,14,8,,,2,62,0.11,0.11,0.29,,0.12
2021-08-13,2021-08-20,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),255,212,16,,,2,485,0.72,1.69,0.58,,0.96
2021-08-13,2021-08-20,Cardiovascular system,Subtotal n (%),312,237,32,,,5,586,0.88,1.89,1.15,,1.16
2021-08-13,2021-08-20,Circulatory system,Cerebral venous (sinus) thrombosis,2,1,11,,,0,14,0.01,0.01,0.40,,0.03
2021-08-13,2021-08-20,Circulatory system,Cerebral thrombosis,2,1,2,,,0,5,0.01,0.01,0.07,,0.01
2021-08-13,2021-08-20,Circulatory system,Cutaneous vasculitis,7,4,0,,,0,11,0.02,0.03,0.00,,0.02
2021-08-13,2021-08-20,Circulatory system,Deep vein thrombosis,87,27,51,,,0,165,0.25,0.21,1.84,,0.33
2021-08-13,2021-08-20,Circulatory system,Embolism,2,1,5,,,0,8,0.01,0.01,0.18,,0.02
2021-08-13,2021-08-20,Circulatory system,Haemorrhage (bleeding),19,8,7,,,0,34,0.05,0.06,0.25,,0.07
2021-08-13,2021-08-20,Circulatory system,Pulmonary embolism,108,38,97,,,1,244,0.31,0.30,3.49,,0.48
2021-08-13,2021-08-20,Circulatory system,Thrombosis (blood clot),72,15,74,,,1,162,0.20,0.12,2.67,,0.32
2021-08-13,2021-08-20,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),15,3,60,,,0,78,0.04,0.02,2.16,,0.15
2021-08-13,2021-08-20,Circulatory system,Subtotal n (%),314,98,307,,,2,721,0.89,0.78,11.06,,1.42
2021-08-13,2021-08-20,Hepato-gastrointestinal and renal system,Acute kidney injury,15,8,3,,,0,26,0.04,0.06,0.11,,0.05
2021-08-13,2021-08-20,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),3,0,1,,,0,4,0.01,0.00,0.04,,0.01
2021-08-13,2021-08-20,Hepato-gastrointestinal and renal system,Liver injury,10,2,3,,,0,15,0.03,0.02,0.11,,0.03
2021-08-13,2021-08-20,Hepato-gastrointestinal and renal system,Subtotal n (%),28,10,7,,,0,45,0.08,0.08,0.25,,0.09
2021-08-13,2021-08-20,Nerves and central nervous system,Bell's Palsy/facial paralysis,235,80,39,,,1,355,0.67,0.64,1.40,,0.70
2021-08-13,2021-08-20,Nerves and central nervous system,Cerebrovascular accident (stroke),67,21,32,,,3,123,0.19,0.17,1.15,,0.24
2021-08-13,2021-08-20,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),11,3,3,,,0,17,0.03,0.02,0.11,,0.03
2021-08-13,2021-08-20,Nerves and central nervous system,Subtotal n (%),313,104,74,,,4,495,0.89,0.83,2.67,,0.98
2021-08-13,2021-08-20,Other system,Anaphylaxis*,128,30,0,,,0,158,0.36,0.24,0.00,,0.31
2021-08-13,2021-08-20,Other system,COVID-19*,92,4,2,,,2,100,0.26,0.03,0.07,,0.20
2021-08-13,2021-08-20,Other system,Subtotal n (%),220,34,2,,,2,258,0.62,0.27,0.07,,0.51
2021-08-13,2021-08-20,Pregnancy outcomes,Fetal growth restriction,5,0,0,,,0,5,0.01,0.00,0.00,,0.01
2021-08-13,2021-08-20,Pregnancy outcomes,Spontaneous abortion,23,6,1,,,0,30,0.07,0.05,0.04,,0.06
2021-08-13,2021-08-20,Pregnancy outcomes,Subtotal n (%),28,6,1,,,0,35,0.08,0.05,0.04,,0.07
2021-08-13,2021-08-20,Respiratory system,Acute respiratory distress syndrome,2,1,0,,,0,3,0.01,0.01,0.00,,0.01
2021-08-13,2021-08-20,Respiratory system,Subtotal n (%),2,1,0,,,0,3,0.01,0.01,0.00,,0.01
2021-08-13,2021-08-20,"Skin and mucous membrane, bone and joints system",Chilblains,7,3,1,,,0,11,0.02,0.02,0.04,,0.02
2021-08-13,2021-08-20,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),10,6,1,,,0,17,0.03,0.05,0.04,,0.03
2021-08-13,2021-08-20,"Skin and mucous membrane, bone and joints system",Subtotal n (%),17,9,2,,,0,28,0.05,0.07,0.07,,0.06
2021-08-13,2021-08-20,All AESI categories,TOTAL,1275,518,494,,,16,2303,3.61,4.12,17.79,,4.55
2021-08-20,2021-08-27,Auto-immune diseases,Guillain-Barré Syndrome,25,12,29,,,0,66,0.07,0.09,1.04,,0.13
2021-08-20,2021-08-27,Auto-immune diseases,Thrombocytopenia (low blood platelets),19,8,38,,,3,68,0.05,0.06,1.37,,0.13
2021-08-20,2021-08-27,Auto-immune diseases,Subtotal n (%),44,20,67,,,3,134,0.12,0.16,2.41,,0.26
2021-08-20,2021-08-27,Cardiovascular system,Cardiac arrest,9,8,5,,,0,22,0.03,0.06,0.18,,0.04
2021-08-20,2021-08-27,Cardiovascular system,Cardiac failure,13,5,3,,,1,22,0.04,0.04,0.11,,0.04
2021-08-20,2021-08-27,Cardiovascular system,Myocardial infarction (heart attack),42,16,8,,,2,68,0.12,0.12,0.29,,0.13
2021-08-20,2021-08-27,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),303,236,16,,,2,557,0.84,1.84,0.58,,1.08
2021-08-20,2021-08-27,Cardiovascular system,Subtotal n (%),367,265,32,,,5,669,1.02,2.07,1.15,,1.30
2021-08-20,2021-08-27,Circulatory system,Cerebral venous (sinus) thrombosis,2,1,11,,,0,14,0.01,0.01,0.40,,0.03
2021-08-20,2021-08-27,Circulatory system,Cerebral thrombosis,2,1,1,,,0,4,0.01,0.01,0.04,,0.01
2021-08-20,2021-08-27,Circulatory system,Cutaneous vasculitis,8,4,0,,,0,12,0.02,0.03,0.00,,0.02
2021-08-20,2021-08-27,Circulatory system,Deep vein thrombosis,91,28,52,,,0,171,0.25,0.22,1.87,,0.33
2021-08-20,2021-08-27,Circulatory system,Embolism,2,1,5,,,0,8,0.01,0.01,0.18,,0.02
2021-08-20,2021-08-27,Circulatory system,Haemorrhage (bleeding),21,8,7,,,0,36,0.06,0.06,0.25,,0.07
2021-08-20,2021-08-27,Circulatory system,Pulmonary embolism,115,40,100,,,1,256,0.32,0.31,3.60,,0.50
2021-08-20,2021-08-27,Circulatory system,Thrombosis (blood clot),75,16,74,,,1,166,0.21,0.12,2.66,,0.32
2021-08-20,2021-08-27,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),15,3,60,,,0,78,0.04,0.02,2.16,,0.15
2021-08-20,2021-08-27,Circulatory system,Subtotal n (%),331,102,310,,,2,745,0.92,0.80,11.15,,1.44
2021-08-20,2021-08-27,Hepato-gastrointestinal and renal system,Acute kidney injury,16,9,3,,,0,28,0.04,0.07,0.11,,0.05
2021-08-20,2021-08-27,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),3,0,1,,,0,4,0.01,0.00,0.04,,0.01
2021-08-20,2021-08-27,Hepato-gastrointestinal and renal system,Liver injury,11,3,3,,,0,17,0.03,0.02,0.11,,0.03
2021-08-20,2021-08-27,Hepato-gastrointestinal and renal system,Subtotal n (%),30,12,7,,,0,49,0.08,0.09,0.25,,0.09
2021-08-20,2021-08-27,Nerves and central nervous system,Bell's Palsy/facial paralysis,265,86,39,,,1,391,0.74,0.67,1.40,,0.76
2021-08-20,2021-08-27,Nerves and central nervous system,Cerebrovascular accident (stroke),69,22,33,,,4,128,0.19,0.17,1.19,,0.25
2021-08-20,2021-08-27,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),11,3,3,,,0,17,0.03,0.02,0.11,,0.03
2021-08-20,2021-08-27,Nerves and central nervous system,Subtotal n (%),345,111,75,,,5,536,0.96,0.87,2.70,,1.04
2021-08-20,2021-08-27,Other system,Anaphylaxis*,130,30,0,,,0,160,0.36,0.23,0.00,,0.31
2021-08-20,2021-08-27,Other system,COVID-19*,96,5,2,,,2,105,0.27,0.04,0.07,,0.20
2021-08-20,2021-08-27,Other system,Subtotal n (%),226,35,2,,,2,265,0.63,0.27,0.07,,0.51
2021-08-20,2021-08-27,Pregnancy outcomes,Fetal growth restriction,5,0,0,,,0,5,0.01,0.00,0.00,,0.01
2021-08-20,2021-08-27,Pregnancy outcomes,Spontaneous abortion,22,6,1,,,0,29,0.06,0.05,0.04,,0.06
2021-08-20,2021-08-27,Pregnancy outcomes,Subtotal n (%),27,6,1,,,0,34,0.08,0.05,0.04,,0.07
2021-08-20,2021-08-27,Respiratory system,Acute respiratory distress syndrome,2,1,0,,,0,3,0.01,0.01,0.00,,0.01
2021-08-20,2021-08-27,Respiratory system,Subtotal n (%),2,1,0,,,0,3,0.01,0.01,0.00,,0.01
2021-08-20,2021-08-27,"Skin and mucous membrane, bone and joints system",Chilblains,7,3,1,,,0,11,0.02,0.02,0.04,,0.02
2021-08-20,2021-08-27,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),10,6,1,,,0,17,0.03,0.05,0.04,,0.03
2021-08-20,2021-08-27,"Skin and mucous membrane, bone and joints system",Subtotal n (%),17,9,2,,,0,28,0.05,0.07,0.07,,0.05
2021-08-20,2021-08-27,All AESI categories,TOTAL,1389,561,496,,,17,2463,3.86,4.38,17.84,,4.77
2021-08-27,2021-09-03,Auto-immune diseases,Guillain-Barré Syndrome,28,15,30,,,0,73,0.08,0.12,1.08,,0.14
2021-08-27,2021-09-03,Auto-immune diseases,Thrombocytopenia (low blood platelets),19,8,38,,,3,68,0.05,0.06,1.37,,0.13
2021-08-27,2021-09-03,Auto-immune diseases,Subtotal n (%),47,23,68,,,3,141,0.13,0.18,2.44,,0.27
2021-08-27,2021-09-03,Cardiovascular system,Cardiac arrest,10,8,5,,,0,23,0.03,0.06,0.18,,0.04
2021-08-27,2021-09-03,Cardiovascular system,Cardiac failure,17,5,3,,,1,26,0.05,0.04,0.11,,0.05
2021-08-27,2021-09-03,Cardiovascular system,Myocardial infarction (heart attack),44,16,8,,,3,71,0.12,0.12,0.29,,0.14
2021-08-27,2021-09-03,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),347,265,17,,,2,631,0.95,2.04,0.61,,1.21
2021-08-27,2021-09-03,Cardiovascular system,Subtotal n (%),418,294,33,,,6,751,1.14,2.26,1.19,,1.43
2021-08-27,2021-09-03,Circulatory system,Cerebral venous (sinus) thrombosis,2,1,11,,,0,14,0.01,0.01,0.40,,0.03
2021-08-27,2021-09-03,Circulatory system,Cerebral thrombosis ,3,1,2,,,0,6,0.01,0.01,0.07,,0.01
2021-08-27,2021-09-03,Circulatory system,Cutaneous vasculitis,11,5,0,,,0,16,0.03,0.04,0.00,,0.03
2021-08-27,2021-09-03,Circulatory system,Deep vein thrombosis,104,30,52,,,0,186,0.28,0.23,1.87,,0.35
2021-08-27,2021-09-03,Circulatory system,Embolism,3,1,5,,,0,9,0.01,0.01,0.18,,0.02
2021-08-27,2021-09-03,Circulatory system,Haemorrhage (bleeding),22,8,8,,,1,39,0.06,0.06,0.29,,0.07
2021-08-27,2021-09-03,Circulatory system,Pulmonary embolism,123,43,101,,,1,268,0.34,0.33,3.63,,0.51
2021-08-27,2021-09-03,Circulatory system,Thrombosis (blood clot),76,19,75,,,1,171,0.21,0.15,2.70,,0.33
2021-08-27,2021-09-03,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),16,4,61,,,0,81,0.04,0.03,2.19,,0.15
2021-08-27,2021-09-03,Circulatory system,Subtotal n (%),360,112,315,,,3,790,0.98,0.86,11.32,,1.51
2021-08-27,2021-09-03,Hepato-gastrointestinal and renal system,Acute kidney injury,16,11,3,,,0,30,0.04,0.08,0.11,,0.06
2021-08-27,2021-09-03,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),3,1,1,,,0,5,0.01,0.01,0.04,,0.01
2021-08-27,2021-09-03,Hepato-gastrointestinal and renal system,Liver injury,11,6,3,,,0,20,0.03,0.05,0.11,,0.04
2021-08-27,2021-09-03,Hepato-gastrointestinal and renal system,Subtotal n (%),30,18,7,,,0,55,0.08,0.14,0.25,,0.10
2021-08-27,2021-09-03,Nerves and central nervous system,Bell's Palsy/facial paralysis*,291,95,41,,,1,428,0.79,0.73,1.47,,0.82
2021-08-27,2021-09-03,Nerves and central nervous system,Cerebrovascular accident (stroke),70,23,34,,,4,131,0.19,0.18,1.22,,0.25
2021-08-27,2021-09-03,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),12,4,4,,,0,20,0.03,0.03,0.14,,0.04
2021-08-27,2021-09-03,Nerves and central nervous system,Subtotal n (%),373,122,79,,,5,579,1.02,0.94,2.84,,1.10
2021-08-27,2021-09-03,Other system,Anaphylaxis*,131,30,0,,,0,161,0.36,0.23,0.00,,0.31
2021-08-27,2021-09-03,Other system,COVID-19*,99,5,2,,,3,109,0.27,0.04,0.07,,0.21
2021-08-27,2021-09-03,Other system,Multisystem inflammatory syndrome,1,1,0,,,0,2,0.00,0.01,0.00,,0.00
2021-08-27,2021-09-03,Other system,Subtotal n (%),231,36,2,,,3,272,0.63,0.28,0.07,,0.52
2021-08-27,2021-09-03,Pregnancy outcomes,Fetal growth restriction,5,0,0,,,0,5,0.01,0.00,0.00,,0.01
2021-08-27,2021-09-03,Pregnancy outcomes,Spontaneous abortion,22,6,1,,,0,29,0.06,0.05,0.04,,0.06
2021-08-27,2021-09-03,Pregnancy outcomes,Subtotal n (%),27,6,1,,,0,34,0.07,0.05,0.04,,0.06
2021-08-27,2021-09-03,Respiratory system,Acute respiratory distress syndrome,2,1,0,,,0,3,0.01,0.01,0.00,,0.01
2021-08-27,2021-09-03,Respiratory system,Subtotal n (%),2,1,0,,,0,3,0.01,0.01,0.00,,0.01
2021-08-27,2021-09-03,"Skin and mucous membrane, bone and joints system",Chilblains,7,3,1,,,0,11,0.02,0.02,0.04,,0.02
2021-08-27,2021-09-03,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),10,9,1,,,0,20,0.03,0.07,0.04,,0.04
2021-08-27,2021-09-03,"Skin and mucous membrane, bone and joints system",Subtotal n (%),17,12,2,,,0,31,0.05,0.09,0.07,,0.06
2021-08-27,2021-09-03,All AESI categories,TOTAL,1505,624,507,,,20,2656,4.11,4.80,18.22,,5.06
2021-09-03,2021-09-10,Auto-immune diseases,Guillain-Barré Syndrome,30,15,30,,,0,75,0.08,0.11,1.08,,0.14
2021-09-03,2021-09-10,Auto-immune diseases,Thrombocytopenia (low blood platelets),20,8,37,,,3,68,0.05,0.06,1.33,,0.13
2021-09-03,2021-09-10,Auto-immune diseases,Subtotal n (%),50,23,67,,,3,143,0.13,0.17,2.41,,0.27
2021-09-03,2021-09-10,Cardiovascular system,Cardiac arrest,10,9,5,,,0,24,0.03,0.07,0.18,,0.05
2021-09-03,2021-09-10,Cardiovascular system,Cardiac failure,17,5,3,,,1,26,0.05,0.04,0.11,,0.05
2021-09-03,2021-09-10,Cardiovascular system,Myocardial infarction (heart attack),45,16,8,,,3,72,0.12,0.12,0.29,,0.14
2021-09-03,2021-09-10,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),384,276,16,,,2,678,1.03,2.09,0.57,,1.27
2021-09-03,2021-09-10,Cardiovascular system,Subtotal n (%),456,306,32,,,6,800,1.23,2.32,1.15,,1.50
2021-09-03,2021-09-10,Circulatory system,Cerebral venous (sinus) thrombosis,2,1,11,,,0,14,0.01,0.01,0.40,,0.03
2021-09-03,2021-09-10,Circulatory system,Cerebral thrombosis ,3,1,2,,,0,6,0.01,0.01,0.07,,0.01
2021-09-03,2021-09-10,Circulatory system,Cutaneous vasculitis,12,5,3,,,0,20,0.03,0.04,0.11,,0.04
2021-09-03,2021-09-10,Circulatory system,Deep vein thrombosis,108,32,53,,,0,193,0.29,0.24,1.90,,0.36
2021-09-03,2021-09-10,Circulatory system,Embolism,3,1,6,,,0,10,0.01,0.01,0.22,,0.02
2021-09-03,2021-09-10,Circulatory system,Haemorrhage (bleeding),21,8,8,,,1,38,0.06,0.06,0.29,,0.07
2021-09-03,2021-09-10,Circulatory system,Pulmonary embolism,128,47,106,,,0,281,0.34,0.36,3.81,,0.53
2021-09-03,2021-09-10,Circulatory system,Thrombosis (blood clot),78,20,75,,,1,174,0.21,0.15,2.69,,0.33
2021-09-03,2021-09-10,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),16,4,61,,,0,81,0.04,0.03,2.19,,0.15
2021-09-03,2021-09-10,Circulatory system,Subtotal n (%),371,119,325,,,2,817,1.00,0.90,11.67,,1.54
2021-09-03,2021-09-10,Hepato-gastrointestinal and renal system,Acute kidney injury,16,11,3,,,0,30,0.04,0.08,0.11,,0.06
2021-09-03,2021-09-10,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),2,1,2,,,0,5,0.01,0.01,0.07,,0.01
2021-09-03,2021-09-10,Hepato-gastrointestinal and renal system,Liver injury,11,6,3,,,0,20,0.03,0.05,0.11,,0.04
2021-09-03,2021-09-10,Hepato-gastrointestinal and renal system,Subtotal n (%),29,18,8,,,0,55,0.08,0.14,0.29,,0.10
2021-09-03,2021-09-10,Nerves and central nervous system,Bell's Palsy/facial paralysis*,310,100,43,,,1,454,0.83,0.76,1.54,,0.85
2021-09-03,2021-09-10,Nerves and central nervous system,Cerebrovascular accident (stroke),73,25,34,,,4,136,0.20,0.19,1.22,,0.26
2021-09-03,2021-09-10,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),13,4,4,,,0,21,0.03,0.03,0.14,,0.04
2021-09-03,2021-09-10,Nerves and central nervous system,Subtotal n (%),396,129,81,,,5,611,1.07,0.98,2.91,,1.15
2021-09-03,2021-09-10,Other system,Anaphylaxis*,132,30,0,,,0,162,0.36,0.23,0.00,,0.30
2021-09-03,2021-09-10,Other system,COVID-19*,102,5,2,,,4,113,0.27,0.04,0.07,,0.21
2021-09-03,2021-09-10,Other system,Multisystem inflammatory syndrome,1,1,0,,,0,2,0.00,0.01,0.00,,0.00
2021-09-03,2021-09-10,Other system,Subtotal n (%),235,36,2,,,4,277,0.63,0.27,0.07,,0.52
2021-09-03,2021-09-10,Pregnancy outcomes,Fetal growth restriction,5,0,0,,,0,5,0.01,0.00,0.00,,0.01
2021-09-03,2021-09-10,Pregnancy outcomes,Spontaneous abortion,23,6,1,,,0,30,0.06,0.05,0.04,,0.06
2021-09-03,2021-09-10,Pregnancy outcomes,Subtotal n (%),28,6,1,,,0,35,0.08,0.05,0.04,,0.07
2021-09-03,2021-09-10,Respiratory system,Acute respiratory distress syndrome,2,1,0,,,0,3,0.01,0.01,0.00,,0.01
2021-09-03,2021-09-10,Respiratory system,Subtotal n (%),2,1,0,,,0,3,0.01,0.01,0.00,,0.01
2021-09-03,2021-09-10,"Skin and mucous membrane, bone and joints system",Chilblains,7,3,1,,,0,11,0.02,0.02,0.04,,0.02
2021-09-03,2021-09-10,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),11,9,1,,,0,21,0.03,0.07,0.04,,0.04
2021-09-03,2021-09-10,"Skin and mucous membrane, bone and joints system",Subtotal n (%),18,12,2,,,0,32,0.05,0.09,0.07,,0.06
2021-09-03,2021-09-10,All AESI categories,TOTAL,1585,650,518,,,20,2773,4.27,4.93,18.60,,5.21
2021-09-10,2021-09-17,Auto-immune diseases,Guillain-Barré Syndrome,31,15,30,,,0,76,0.08,0.11,1.08,,0.14
2021-09-10,2021-09-17,Auto-immune diseases,Thrombocytopenia (low blood platelets),20,7,41,,,3,71,0.05,0.05,1.47,,0.13
2021-09-10,2021-09-17,Auto-immune diseases,Subtotal n (%),51,22,71,,,3,147,0.14,0.16,2.55,,0.27
2021-09-10,2021-09-17,Cardiovascular system,Cardiac arrest,10,9,5,,,0,24,0.03,0.07,0.18,,0.04
2021-09-10,2021-09-17,Cardiovascular system,Cardiac failure,18,5,3,,,1,27,0.05,0.04,0.11,,0.05
2021-09-10,2021-09-17,Cardiovascular system,Myocardial infarction (heart attack),46,15,6,,,3,70,0.12,0.11,0.22,,0.13
2021-09-10,2021-09-17,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),408,290,18,,,2,718,1.08,2.17,0.65,,1.34
2021-09-10,2021-09-17,Cardiovascular system,Subtotal n (%),482,319,32,,,6,839,1.28,2.39,1.15,,1.56
2021-09-10,2021-09-17,Circulatory system,Cerebral venous (sinus) thrombosis,2,1,12,,,0,15,0.01,0.01,0.43,,0.03
2021-09-10,2021-09-17,Circulatory system,Cerebral thrombosis ,3,1,2,,,0,6,0.01,0.01,0.07,,0.01
2021-09-10,2021-09-17,Circulatory system,Cutaneous vasculitis,12,5,3,,,0,20,0.03,0.04,0.11,,0.04
2021-09-10,2021-09-17,Circulatory system,Deep vein thrombosis,110,33,53,,,0,196,0.29,0.25,1.90,,0.36
2021-09-10,2021-09-17,Circulatory system,Embolism,3,1,6,,,0,10,0.01,0.01,0.22,,0.02
2021-09-10,2021-09-17,Circulatory system,Haemorrhage (bleeding),24,8,8,,,1,41,0.06,0.06,0.29,,0.08
2021-09-10,2021-09-17,Circulatory system,Pulmonary embolism,134,49,107,,,0,290,0.36,0.37,3.84,,0.54
2021-09-10,2021-09-17,Circulatory system,Thrombosis (blood clot),78,20,79,,,1,178,0.21,0.15,2.84,,0.33
2021-09-10,2021-09-17,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),16,4,61,,,0,81,0.04,0.03,2.19,,0.15
2021-09-10,2021-09-17,Circulatory system,Subtotal n (%),382,122,331,,,2,837,1.02,0.91,11.88,,1.56
2021-09-10,2021-09-17,Hepato-gastrointestinal and renal system,Acute kidney injury,16,11,3,,,0,30,0.04,0.08,0.11,,0.06
2021-09-10,2021-09-17,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),2,1,2,,,0,5,0.01,0.01,0.07,,0.01
2021-09-10,2021-09-17,Hepato-gastrointestinal and renal system,Liver injury,11,6,3,,,0,20,0.03,0.04,0.11,,0.04
2021-09-10,2021-09-17,Hepato-gastrointestinal and renal system,Subtotal n (%),29,18,8,,,0,55,0.08,0.13,0.29,,0.10
2021-09-10,2021-09-17,Nerves and central nervous system,Bell's Palsy/facial paralysis*,325,105,43,,,1,474,0.86,0.79,1.54,,0.88
2021-09-10,2021-09-17,Nerves and central nervous system,Cerebrovascular accident (stroke),75,27,35,,,3,140,0.20,0.20,1.26,,0.26
2021-09-10,2021-09-17,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),14,4,4,,,0,22,0.04,0.03,0.14,,0.04
2021-09-10,2021-09-17,Nerves and central nervous system,Subtotal n (%),414,136,82,,,4,636,1.10,1.02,2.94,,1.18
2021-09-10,2021-09-17,Other system,Anaphylaxis*,142,30,0,,,0,172,0.38,0.22,0.00,,0.32
2021-09-10,2021-09-17,Other system,COVID-19*,108,5,2,,,4,119,0.29,0.04,0.07,,0.22
2021-09-10,2021-09-17,Other system,Multisystem inflammatory syndrome,1,1,0,,,0,2,0.00,0.01,0.00,,0.00
2021-09-10,2021-09-17,Other system,Subtotal n (%),251,36,2,,,4,293,0.67,0.27,0.07,,0.54
2021-09-10,2021-09-17,Pregnancy outcomes,Fetal growth restriction,5,0,0,,,0,5,0.01,0.00,0.00,,0.01
2021-09-10,2021-09-17,Pregnancy outcomes,Spontaneous abortion,24,6,1,,,0,31,0.06,0.04,0.04,,0.06
2021-09-10,2021-09-17,Pregnancy outcomes,Subtotal n (%),29,6,1,,,0,36,0.08,0.04,0.04,,0.07
2021-09-10,2021-09-17,Respiratory system,Acute respiratory distress syndrome,2,1,0,,,0,3,0.01,0.01,0.00,,0.01
2021-09-10,2021-09-17,Respiratory system,Subtotal n (%),2,1,0,,,0,3,0.01,0.01,0.00,,0.01
2021-09-10,2021-09-17,"Skin and mucous membrane, bone and joints system",Chilblains,7,3,1,,,0,11,0.02,0.02,0.04,,0.02
2021-09-10,2021-09-17,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),12,9,1,,,0,22,0.03,0.07,0.04,,0.04
2021-09-10,2021-09-17,"Skin and mucous membrane, bone and joints system",Subtotal n (%),19,12,2,,,0,33,0.05,0.09,0.07,,0.06
2021-09-10,2021-09-17,All AESI categories,TOTAL,1659,672,529,,,19,2879,4.41,5.04,18.99,,5.35
2021-09-17,2021-09-24,Auto-immune diseases,Guillain-Barré Syndrome,33,16,30,,,0,79,0.09,0.12,1.08,,0.15
2021-09-17,2021-09-24,Auto-immune diseases,Thrombocytopenia (low blood platelets),19,7,37,,,3,66,0.05,0.05,1.33,,0.12
2021-09-17,2021-09-24,Auto-immune diseases,Subtotal n (%),52,23,67,,,3,145,0.14,0.17,2.40,,0.27
2021-09-17,2021-09-24,Cardiovascular system,Cardiac arrest,10,9,5,,,0,24,0.03,0.07,0.18,,0.04
2021-09-17,2021-09-24,Cardiovascular system,Cardiac failure,19,5,3,,,1,28,0.05,0.04,0.11,,0.05
2021-09-17,2021-09-24,Cardiovascular system,Myocardial infarction (heart attack),46,16,6,,,3,71,0.12,0.12,0.22,,0.13
2021-09-17,2021-09-24,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),445,306,19,,,4,774,1.17,2.27,0.68,,1.42
2021-09-17,2021-09-24,Cardiovascular system,Subtotal n (%),520,336,33,,,8,897,1.37,2.49,1.18,,1.65
2021-09-17,2021-09-24,Circulatory system,Cerebral venous (sinus) thrombosis,2,1,11,,,0,14,0.01,0.01,0.39,,0.03
2021-09-17,2021-09-24,Circulatory system,Cerebral thrombosis ,3,1,2,,,0,6,0.01,0.01,0.07,,0.01
2021-09-17,2021-09-24,Circulatory system,Cutaneous vasculitis,12,5,4,,,0,21,0.03,0.04,0.14,,0.04
2021-09-17,2021-09-24,Circulatory system,Deep vein thrombosis,114,34,53,,,0,201,0.30,0.25,1.90,,0.37
2021-09-17,2021-09-24,Circulatory system,Embolism,3,1,7,,,0,11,0.01,0.01,0.25,,0.02
2021-09-17,2021-09-24,Circulatory system,Haemorrhage (bleeding),24,9,9,,,1,43,0.06,0.07,0.32,,0.08
2021-09-17,2021-09-24,Circulatory system,Pulmonary embolism,137,51,108,,,0,296,0.36,0.38,3.88,,0.54
2021-09-17,2021-09-24,Circulatory system,Thrombosis (blood clot),83,23,78,,,1,185,0.22,0.17,2.80,,0.34
2021-09-17,2021-09-24,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),16,4,61,,,0,81,0.04,0.03,2.19,,0.15
2021-09-17,2021-09-24,Circulatory system,Subtotal n (%),394,129,333,,,2,858,1.04,0.96,11.95,,1.58
2021-09-17,2021-09-24,Hepato-gastrointestinal and renal system,Acute kidney injury,16,11,3,,,0,30,0.04,0.08,0.11,,0.06
2021-09-17,2021-09-24,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),2,1,2,,,0,5,0.01,0.01,0.07,,0.01
2021-09-17,2021-09-24,Hepato-gastrointestinal and renal system,Liver injury,12,6,3,,,0,21,0.03,0.04,0.11,,0.04
2021-09-17,2021-09-24,Hepato-gastrointestinal and renal system,Subtotal n (%),30,18,8,,,0,56,0.08,0.13,0.29,,0.10
2021-09-17,2021-09-24,Nerves and central nervous system,Bell's Palsy/facial paralysis*,340,110,43,,,1,494,0.89,0.82,1.54,,0.91
2021-09-17,2021-09-24,Nerves and central nervous system,Cerebrovascular accident (stroke),76,29,34,,,3,142,0.20,0.22,1.22,,0.26
2021-09-17,2021-09-24,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),17,5,4,,,0,26,0.04,0.04,0.14,,0.05
2021-09-17,2021-09-24,Nerves and central nervous system,Subtotal n (%),433,144,81,,,4,662,1.14,1.07,2.91,,1.22
2021-09-17,2021-09-24,Other system,Anaphylaxis*,157,40,4,,,0,201,0.41,0.30,0.14,,0.37
2021-09-17,2021-09-24,Other system,COVID-19*,108,5,2,,,4,119,0.28,0.04,0.07,,0.22
2021-09-17,2021-09-24,Other system,Multisystem inflammatory syndrome,1,1,0,,,0,2,0.00,0.01,0.00,,0.00
2021-09-17,2021-09-24,Other system,Subtotal n (%),266,46,6,,,4,322,0.70,0.34,0.22,,0.59
2021-09-17,2021-09-24,Pregnancy outcomes,Fetal growth restriction,5,0,0,,,0,5,0.01,0.00,0.00,,0.01
2021-09-17,2021-09-24,Pregnancy outcomes,Spontaneous abortion,27,6,1,,,0,34,0.07,0.04,0.04,,0.06
2021-09-17,2021-09-24,Pregnancy outcomes,Subtotal n (%),32,6,1,,,0,39,0.08,0.04,0.04,,0.07
2021-09-17,2021-09-24,Respiratory system,Acute respiratory distress syndrome,2,1,0,,,0,3,0.01,0.01,0.00,,0.01
2021-09-17,2021-09-24,Respiratory system,Subtotal n (%),2,1,0,,,0,3,0.01,0.01,0.00,,0.01
2021-09-17,2021-09-24,"Skin and mucous membrane, bone and joints system",Chilblains,9,3,1,,,0,13,0.02,0.02,0.04,,0.02
2021-09-17,2021-09-24,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),13,9,1,,,0,23,0.03,0.07,0.04,,0.04
2021-09-17,2021-09-24,"Skin and mucous membrane, bone and joints system",Subtotal n (%),22,12,2,,,0,36,0.06,0.09,0.07,,0.07
2021-09-17,2021-09-24,All AESI categories,TOTAL,1751,715,531,,,21,3018,4.60,5.31,19.06,,5.55
2021-09-24,2021-10-01,Auto-immune diseases,Guillain-Barré Syndrome,33,18,31,,,0,82,0.09,0.13,1.11,,0.15
2021-09-24,2021-10-01,Auto-immune diseases,Thrombocytopenia (low blood platelets),17,8,36,,,3,64,0.04,0.06,1.29,,0.12
2021-09-24,2021-10-01,Auto-immune diseases,Subtotal n (%),50,26,67,,,3,146,0.13,0.19,2.40,,0.27
2021-09-24,2021-10-01,Cardiovascular system,Cardiac arrest,10,9,5,,,0,24,0.03,0.07,0.18,,0.04
2021-09-24,2021-10-01,Cardiovascular system,Cardiac failure,19,5,3,,,1,28,0.05,0.04,0.11,,0.05
2021-09-24,2021-10-01,Cardiovascular system,Myocardial infarction (heart attack),46,16,6,,,4,72,0.12,0.12,0.22,,0.13
2021-09-24,2021-10-01,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),466,321,21,,,4,812,1.21,2.36,0.75,,1.48
2021-09-24,2021-10-01,Cardiovascular system,Subtotal n (%),541,351,35,,,9,936,1.40,2.58,1.26,,1.70
2021-09-24,2021-10-01,Circulatory system,Cerebral venous (sinus) thrombosis,2,1,11,,,0,14,0.01,0.01,0.39,,0.03
2021-09-24,2021-10-01,Circulatory system,Cerebral thrombosis ,4,2,1,,,0,7,0.01,0.01,0.04,,0.01
2021-09-24,2021-10-01,Circulatory system,Cutaneous vasculitis,12,5,4,,,0,21,0.03,0.04,0.14,,0.04
2021-09-24,2021-10-01,Circulatory system,Deep vein thrombosis,115,36,53,,,0,204,0.30,0.26,1.90,,0.37
2021-09-24,2021-10-01,Circulatory system,Embolism,3,1,7,,,0,11,0.01,0.01,0.25,,0.02
2021-09-24,2021-10-01,Circulatory system,Haemorrhage (bleeding),24,9,9,,,1,43,0.06,0.07,0.32,,0.08
2021-09-24,2021-10-01,Circulatory system,Pulmonary embolism,141,52,108,,,0,301,0.37,0.38,3.87,,0.55
2021-09-24,2021-10-01,Circulatory system,Thrombosis (blood clot),86,24,78,,,1,189,0.22,0.18,2.80,,0.34
2021-09-24,2021-10-01,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),16,5,61,,,0,82,0.04,0.04,2.19,,0.15
2021-09-24,2021-10-01,Circulatory system,Subtotal n (%),403,135,332,,,2,872,1.05,0.99,11.91,,1.59
2021-09-24,2021-10-01,Hepato-gastrointestinal and renal system,Acute kidney injury,16,12,3,,,0,31,0.04,0.09,0.11,,0.06
2021-09-24,2021-10-01,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),4,1,1,,,0,6,0.01,0.01,0.04,,0.01
2021-09-24,2021-10-01,Hepato-gastrointestinal and renal system,Liver injury,12,6,3,,,0,21,0.03,0.04,0.11,,0.04
2021-09-24,2021-10-01,Hepato-gastrointestinal and renal system,Subtotal n (%),29,19,6,,,0,54,0.08,0.14,0.22,,0.10
2021-09-24,2021-10-01,Nerves and central nervous system,Bell's Palsy/facial paralysis*,364,117,44,,,1,526,0.94,0.86,1.58,,0.96
2021-09-24,2021-10-01,Nerves and central nervous system,Cerebrovascular accident (stroke),79,28,34,,,3,144,0.20,0.21,1.22,,0.26
2021-09-24,2021-10-01,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),18,5,4,,,0,27,0.05,0.04,0.14,,0.05
2021-09-24,2021-10-01,Nerves and central nervous system,Subtotal n (%),461,150,82,,,4,697,1.20,1.10,2.94,,1.27
2021-09-24,2021-10-01,Other system,Anaphylaxis*,202,54,12,,,0,268,0.52,0.40,0.43,,0.49
2021-09-24,2021-10-01,Other system,COVID-19*,111,5,2,,,5,123,0.29,0.04,0.07,,0.22
2021-09-24,2021-10-01,Other system,Multisystem inflammatory syndrome,1,1,0,,,0,2,0.00,0.01,0.00,,0.00
2021-09-24,2021-10-01,Other system,Subtotal n (%),314,60,14,,,5,393,0.81,0.44,0.50,,0.71
2021-09-24,2021-10-01,Pregnancy outcomes,Fetal growth restriction,5,0,0,,,0,5,0.01,0.00,0.00,,0.01
2021-09-24,2021-10-01,Pregnancy outcomes,Spontaneous abortion,28,7,1,,,0,36,0.07,0.05,0.04,,0.07
2021-09-24,2021-10-01,Pregnancy outcomes,Subtotal n (%),33,7,1,,,0,41,0.09,0.05,0.04,,0.07
2021-09-24,2021-10-01,Respiratory system,Acute respiratory distress syndrome,2,1,0,,,0,3,0.01,0.01,0.00,,0.01
2021-09-24,2021-10-01,Respiratory system,Subtotal n (%),2,1,0,,,0,3,0.01,0.01,0.00,,0.01
2021-09-24,2021-10-01,"Skin and mucous membrane, bone and joints system",Chilblains,9,3,1,,,0,13,0.02,0.02,0.04,,0.02
2021-09-24,2021-10-01,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),13,9,1,,,0,23,0.03,0.07,0.04,,0.04
2021-09-24,2021-10-01,"Skin and mucous membrane, bone and joints system",Subtotal n (%),22,12,2,,,0,36,0.06,0.09,0.07,,0.07
2021-09-24,2021-10-01,All AESI categories,TOTAL,1855,761,539,,,23,3178,4.81,5.59,19.33,,5.78
2021-10-01,2021-10-08,Auto-immune diseases,Guillain-Barré Syndrome,33,19,31,,,0,83,0.08,0.14,1.11,,0.15
2021-10-01,2021-10-08,Auto-immune diseases,Thrombocytopenia (low blood platelets),18,8,36,,,3,65,0.05,0.06,1.29,,0.12
2021-10-01,2021-10-08,Auto-immune diseases,Subtotal n (%),51,27,67,,,3,148,0.13,0.20,2.40,,0.27
2021-10-01,2021-10-08,Cardiovascular system,Cardiac arrest,11,9,5,,,0,25,0.03,0.07,0.18,,0.05
2021-10-01,2021-10-08,Cardiovascular system,Cardiac failure,19,5,3,,,1,28,0.05,0.04,0.11,,0.05
2021-10-01,2021-10-08,Cardiovascular system,Myocardial infarction (heart attack),47,16,6,,,4,73,0.12,0.12,0.22,,0.13
2021-10-01,2021-10-08,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),501,333,20,,,5,859,1.28,2.44,0.72,,1.55
2021-10-01,2021-10-08,Cardiovascular system,Subtotal n (%),578,363,34,,,10,985,1.48,2.66,1.22,,1.77
2021-10-01,2021-10-08,Circulatory system,Cerebral venous (sinus) thrombosis,3,0,8,,,0,11,0.01,0.00,0.29,,0.02
2021-10-01,2021-10-08,Circulatory system,Cerebral thrombosis,4,2,1,,,0,7,0.01,0.01,0.04,,0.01
2021-10-01,2021-10-08,Circulatory system,Cutaneous vasculitis,12,5,4,,,0,21,0.03,0.04,0.14,,0.04
2021-10-01,2021-10-08,Circulatory system,Deep vein thrombosis,117,37,54,,,0,208,0.30,0.27,1.94,,0.37
2021-10-01,2021-10-08,Circulatory system,Embolism,3,1,7,,,0,11,0.01,0.01,0.25,,0.02
2021-10-01,2021-10-08,Circulatory system,Haemorrhage (bleeding),25,9,9,,,1,44,0.06,0.07,0.32,,0.08
2021-10-01,2021-10-08,Circulatory system,Pulmonary embolism,144,54,110,,,0,308,0.37,0.40,3.94,,0.55
2021-10-01,2021-10-08,Circulatory system,Thrombosis (blood clot),94,25,79,,,2,200,0.24,0.18,2.83,,0.36
2021-10-01,2021-10-08,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),16,5,61,,,0,82,0.04,0.04,2.19,,0.15
2021-10-01,2021-10-08,Circulatory system,Subtotal n (%),418,138,333,,,3,892,1.07,1.01,11.94,,1.61
2021-10-01,2021-10-08,Hepato-gastrointestinal and renal system,Acute kidney injury,17,12,3,,,0,32,0.04,0.09,0.11,,0.06
2021-10-01,2021-10-08,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),4,2,0,,,0,6,0.01,0.01,0.00,,0.01
2021-10-01,2021-10-08,Hepato-gastrointestinal and renal system,Liver injury,12,6,3,,,0,21,0.03,0.04,0.11,,0.04
2021-10-01,2021-10-08,Hepato-gastrointestinal and renal system,Subtotal n (%),33,20,6,,,0,59,0.08,0.15,0.22,,0.11
2021-10-01,2021-10-08,Nerves and central nervous system,Bell's Palsy/facial paralysis*,378,121,44,,,2,545,0.97,0.89,1.58,,0.98
2021-10-01,2021-10-08,Nerves and central nervous system,Cerebrovascular accident (stroke),83,28,34,,,3,148,0.21,0.21,1.22,,0.27
2021-10-01,2021-10-08,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),19,5,4,,,0,28,0.05,0.04,0.14,,0.05
2021-10-01,2021-10-08,Nerves and central nervous system,Subtotal n (%),480,154,82,,,5,721,1.23,1.13,2.94,,1.30
2021-10-01,2021-10-08,Other system,Anaphylaxis*,233,61,13,,,0,307,0.60,0.45,0.47,,0.55
2021-10-01,2021-10-08,Other system,COVID-19*,112,6,2,,,6,126,0.29,0.04,0.07,,0.23
2021-10-01,2021-10-08,Other system,Multisystem inflammatory syndrome,1,1,0,,,0,2,0.00,0.01,0.00,,0.00
2021-10-01,2021-10-08,Other system,Subtotal n (%),346,68,15,,,6,435,0.89,0.50,0.54,,0.78
2021-10-01,2021-10-08,Pregnancy outcomes,Fetal growth restriction,5,0,0,,,0,5,0.01,0.00,0.00,,0.01
2021-10-01,2021-10-08,Pregnancy outcomes,Spontaneous abortion,29,7,1,,,0,37,0.07,0.05,0.04,,0.07
2021-10-01,2021-10-08,Pregnancy outcomes,Subtotal n (%),34,7,1,,,0,42,0.09,0.05,0.04,,0.08
2021-10-01,2021-10-08,Respiratory system,Acute respiratory distress syndrome,2,1,0,,,0,3,0.01,0.01,0.00,,0.01
2021-10-01,2021-10-08,Respiratory system,Subtotal n (%),2,1,0,,,0,3,0.01,0.01,0.00,,0.01
2021-10-01,2021-10-08,"Skin and mucous membrane, bone and joints system",Chilblains,9,3,1,,,0,13,0.02,0.02,0.04,,0.02
2021-10-01,2021-10-08,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),14,9,1,,,0,24,0.04,0.07,0.04,,0.04
2021-10-01,2021-10-08,"Skin and mucous membrane, bone and joints system",Subtotal n (%),23,12,2,,,0,37,0.06,0.09,0.07,,0.07
2021-10-01,2021-10-08,All AESI categories,TOTAL,1965,790,540,,,27,3322,5.03,5.79,19.36,,5.98
2021-10-08,2021-10-18,Auto-immune diseases,Guillain-Barré Syndrome,34,19,32,,,0,85,0.09,0.14,1.15,,0.15
2021-10-08,2021-10-18,Auto-immune diseases,Thrombocytopenia (low blood platelets),18,8,35,,,3,64,0.05,0.06,1.25,,0.11
2021-10-08,2021-10-18,Auto-immune diseases,Subtotal n (%),52,27,67,,,3,149,0.13,0.19,2.40,,0.27
2021-10-08,2021-10-18,Cardiovascular system,Cardiac arrest,13,10,5,,,0,28,0.03,0.07,0.18,,0.05
2021-10-08,2021-10-18,Cardiovascular system,Cardiac failure,19,7,3,,,1,30,0.05,0.05,0.11,,0.05
2021-10-08,2021-10-18,Cardiovascular system,Myocardial infarction (heart attack),47,16,6,,,4,73,0.12,0.12,0.22,,0.13
2021-10-08,2021-10-18,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),540,348,20,,,5,913,1.37,2.51,0.72,,1.62
2021-10-08,2021-10-18,Cardiovascular system,Subtotal n (%),619,381,34,,,10,1044,1.57,2.74,1.22,,1.86
2021-10-08,2021-10-18,Circulatory system,Cerebral venous (sinus) thrombosis,3,1,11,,,0,15,0.01,0.01,0.39,,0.03
2021-10-08,2021-10-18,Circulatory system,Cerebral thrombosis ,4,2,1,,,0,7,0.01,0.01,0.04,,0.01
2021-10-08,2021-10-18,Circulatory system,Cutaneous vasculitis,14,5,4,,,0,23,0.04,0.04,0.14,,0.04
2021-10-08,2021-10-18,Circulatory system,Deep vein thrombosis,117,37,55,,,0,209,0.30,0.27,1.97,,0.37
2021-10-08,2021-10-18,Circulatory system,Embolism,3,1,7,,,0,11,0.01,0.01,0.25,,0.02
2021-10-08,2021-10-18,Circulatory system,Haemorrhage (bleeding),27,10,9,,,1,47,0.07,0.07,0.32,,0.08
2021-10-08,2021-10-18,Circulatory system,Pulmonary embolism,150,56,111,,,0,317,0.38,0.40,3.98,,0.56
2021-10-08,2021-10-18,Circulatory system,Thrombosis (blood clot),98,25,79,,,2,204,0.25,0.18,2.83,,0.36
2021-10-08,2021-10-18,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),16,5,61,,,0,82,0.04,0.04,2.19,,0.15
2021-10-08,2021-10-18,Circulatory system,Subtotal n (%),432,142,338,,,3,915,1.09,1.02,12.11,,1.63
2021-10-08,2021-10-18,Hepato-gastrointestinal and renal system,Acute kidney injury,17,12,3,,,0,32,0.04,0.09,0.11,,0.06
2021-10-08,2021-10-18,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),4,1,0,,,0,5,0.01,0.01,0.00,,0.01
2021-10-08,2021-10-18,Hepato-gastrointestinal and renal system,Liver injury,14,8,3,,,0,25,0.04,0.06,0.11,,0.04
2021-10-08,2021-10-18,Hepato-gastrointestinal and renal system,Subtotal n (%),35,21,6,,,0,62,0.09,0.15,0.22,,0.11
2021-10-08,2021-10-18,Nerves and central nervous system,Bell's Palsy/facial paralysis*,396,122,44,,,2,564,1.00,0.88,1.58,,1.00
2021-10-08,2021-10-18,Nerves and central nervous system,Cerebrovascular accident (stroke),85,29,34,,,3,151,0.22,0.21,1.22,,0.27
2021-10-08,2021-10-18,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),19,7,4,,,0,30,0.05,0.05,0.14,,0.05
2021-10-08,2021-10-18,Nerves and central nervous system,Subtotal n (%),500,158,82,,,5,745,1.27,1.14,2.94,,1.33
2021-10-08,2021-10-18,Other system,Anaphylaxis*,278,74,16,,,0,368,0.70,0.53,0.57,,0.65
2021-10-08,2021-10-18,Other system,COVID-19*,120,6,2,,,6,134,0.30,0.04,0.07,,0.24
2021-10-08,2021-10-18,Other system,Multisystem inflammatory syndrome,1,1,0,,,0,2,0.00,0.01,0.00,,0.00
2021-10-08,2021-10-18,Other system,Subtotal n (%),399,81,18,,,6,504,1.01,0.58,0.65,,0.90
2021-10-08,2021-10-18,Pregnancy outcomes,Fetal growth restriction,5,0,0,,,0,5,0.01,0.00,0.00,,0.01
2021-10-08,2021-10-18,Pregnancy outcomes,Spontaneous abortion,29,7,1,,,0,37,0.07,0.05,0.04,,0.07
2021-10-08,2021-10-18,Pregnancy outcomes,Subtotal n (%),34,7,1,,,0,42,0.09,0.05,0.04,,0.07
2021-10-08,2021-10-18,Respiratory system,Acute respiratory distress syndrome,2,1,0,,,0,3,0.01,0.01,0.00,,0.01
2021-10-08,2021-10-18,Respiratory system,Subtotal n (%),2,1,0,,,0,3,0.01,0.01,0.00,,0.01
2021-10-08,2021-10-18,"Skin and mucous membrane, bone and joints system",Chilblains,9,3,1,,,0,13,0.02,0.02,0.04,,0.02
2021-10-08,2021-10-18,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),14,9,1,,,0,24,0.04,0.06,0.04,,0.04
2021-10-08,2021-10-18,"Skin and mucous membrane, bone and joints system",Subtotal n (%),23,12,2,,,0,37,0.06,0.09,0.07,,0.07
2021-10-08,2021-10-18,All AESI categories,TOTAL,2096,830,548,,,27,3501,5.31,5.98,19.64,,6.23
2021-10-15,2021-10-22,Auto-immune diseases,Guillain-Barré Syndrome,34,19,32,,,0,85,0.09,0.14,1.15,,0.15
2021-10-15,2021-10-22,Auto-immune diseases,Thrombocytopenia (low blood platelets),19,8,35,,,3,65,0.05,0.06,1.25,,0.11
2021-10-15,2021-10-22,Auto-immune diseases,Subtotal n (%),53,27,67,,,3,150,0.13,0.19,2.40,,0.26
2021-10-15,2021-10-22,Cardiovascular system,Cardiac arrest,16,10,5,,,0,31,0.04,0.07,0.18,,0.05
2021-10-15,2021-10-22,Cardiovascular system,Cardiac failure,19,8,3,,,1,31,0.05,0.06,0.11,,0.05
2021-10-15,2021-10-22,Cardiovascular system,Myocardial infarction (heart attack),48,18,6,,,4,76,0.12,0.13,0.21,,0.13
2021-10-15,2021-10-22,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),573,357,21,,,5,956,1.44,2.55,0.75,,1.68
2021-10-15,2021-10-22,Cardiovascular system,Subtotal n (%),656,393,35,,,10,1094,1.64,2.80,1.25,,1.93
2021-10-15,2021-10-22,Circulatory system,Cerebral venous (sinus) thrombosis,3,1,11,,,0,15,0.01,0.01,0.39,,0.03
2021-10-15,2021-10-22,Circulatory system,Cerebral thrombosis ,5,2,1,,,0,8,0.01,0.01,0.04,,0.01
2021-10-15,2021-10-22,Circulatory system,Cutaneous vasculitis,15,6,4,,,0,25,0.04,0.04,0.14,,0.04
2021-10-15,2021-10-22,Circulatory system,Deep vein thrombosis,118,38,56,,,0,212,0.30,0.27,2.01,,0.37
2021-10-15,2021-10-22,Circulatory system,Embolism,3,1,7,,,0,11,0.01,0.01,0.25,,0.02
2021-10-15,2021-10-22,Circulatory system,Haemorrhage (bleeding),29,10,9,,,1,49,0.07,0.07,0.32,,0.09
2021-10-15,2021-10-22,Circulatory system,Pulmonary embolism,152,57,112,,,0,321,0.38,0.41,4.01,,0.57
2021-10-15,2021-10-22,Circulatory system,Thrombosis (blood clot),102,25,80,,,2,209,0.26,0.18,2.87,,0.37
2021-10-15,2021-10-22,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),16,5,61,,,0,82,0.04,0.04,2.18,,0.14
2021-10-15,2021-10-22,Circulatory system,Subtotal n (%),443,145,341,,,3,932,1.11,1.03,12.21,,1.64
2021-10-15,2021-10-22,Hepato-gastrointestinal and renal system,Acute kidney injury,18,14,3,,,0,35,0.05,0.10,0.11,,0.06
2021-10-15,2021-10-22,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),4,1,0,,,0,5,0.01,0.01,0.00,,0.01
2021-10-15,2021-10-22,Hepato-gastrointestinal and renal system,Liver injury,14,8,3,,,0,25,0.04,0.06,0.11,,0.04
2021-10-15,2021-10-22,Hepato-gastrointestinal and renal system,Subtotal n (%),36,23,6,,,0,65,0.09,0.16,0.21,,0.11
2021-10-15,2021-10-22,Nerves and central nervous system,Bell's Palsy/facial paralysis*,406,122,44,,,2,574,1.02,0.87,1.58,,1.01
2021-10-15,2021-10-22,Nerves and central nervous system,Cerebrovascular accident (stroke),85,30,34,,,3,152,0.21,0.21,1.22,,0.27
2021-10-15,2021-10-22,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),20,7,4,,,0,31,0.05,0.05,0.14,,0.05
2021-10-15,2021-10-22,Nerves and central nervous system,Subtotal n (%),511,159,82,,,5,757,1.28,1.13,2.94,,1.33
2021-10-15,2021-10-22,Other system,Anaphylaxis*,314,89,16,,,0,419,0.79,0.64,0.57,,0.74
2021-10-15,2021-10-22,Other system,COVID-19*,122,6,2,,,8,138,0.31,0.04,0.07,,0.24
2021-10-15,2021-10-22,Other system,Multisystem inflammatory syndrome,1,1,0,,,0,2,0.00,0.01,0.00,,0.00
2021-10-15,2021-10-22,Other system,Subtotal n (%),437,96,18,,,8,559,1.10,0.69,0.64,,0.99
2021-10-15,2021-10-22,Pregnancy outcomes,Fetal growth restriction,5,0,0,,,0,5,0.01,0.00,0.00,,0.01
2021-10-15,2021-10-22,Pregnancy outcomes,Spontaneous abortion,30,7,1,,,0,38,0.08,0.05,0.04,,0.07
2021-10-15,2021-10-22,Pregnancy outcomes,Subtotal n (%),35,7,1,,,0,43,0.09,0.05,0.04,,0.08
2021-10-15,2021-10-22,Respiratory system,Acute respiratory distress syndrome,2,1,0,,,0,3,0.01,0.01,0.00,,0.01
2021-10-15,2021-10-22,Respiratory system,Subtotal n (%),2,1,0,,,0,3,0.01,0.01,0.00,,0.01
2021-10-15,2021-10-22,"Skin and mucous membrane, bone and joints system",Chilblains,8,3,1,,,0,12,0.02,0.02,0.04,,0.02
2021-10-15,2021-10-22,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),17,10,1,,,0,28,0.04,0.07,0.04,,0.05
2021-10-15,2021-10-22,"Skin and mucous membrane, bone and joints system",Subtotal n (%),25,13,2,,,0,40,0.06,0.09,0.07,,0.07
2021-10-15,2021-10-22,All AESI categories,TOTAL,2198,864,552,,,29,3643,5.51,6.17,19.77,,6.42
2021-10-22,2021-10-29,Auto-immune diseases,Guillain-Barré Syndrome,41,21,35,,,0,97,0.10,0.15,1.25,,0.17
2021-10-22,2021-10-29,Auto-immune diseases,Thrombocytopenia (low blood platelets),20,10,36,,,3,69,0.05,0.07,1.29,,0.12
2021-10-22,2021-10-29,Auto-immune diseases,Subtotal n (%),61,31,71,,,3,166,0.15,0.22,2.54,,0.29
2021-10-22,2021-10-29,Cardiovascular system,Cardiac arrest,17,10,5,,,0,32,0.04,0.07,0.18,,0.06
2021-10-22,2021-10-29,Cardiovascular system,Cardiac failure,20,8,3,,,1,32,0.05,0.06,0.11,,0.06
2021-10-22,2021-10-29,Cardiovascular system,Myocardial infarction (heart attack),50,18,6,,,3,77,0.12,0.13,0.21,,0.13
2021-10-22,2021-10-29,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),584,360,21,,,5,970,1.45,2.55,0.75,,1.69
2021-10-22,2021-10-29,Cardiovascular system,Subtotal n (%),671,396,35,,,9,1111,1.67,2.80,1.25,,1.94
2021-10-22,2021-10-29,Circulatory system,Cerebral venous (sinus) thrombosis,3,2,10,,,0,15,0.01,0.01,0.36,,0.03
2021-10-22,2021-10-29,Circulatory system,Cerebral thrombosis ,5,3,1,,,0,9,0.01,0.02,0.04,,0.02
2021-10-22,2021-10-29,Circulatory system,Cutaneous vasculitis,15,6,4,,,0,25,0.04,0.04,0.14,,0.04
2021-10-22,2021-10-29,Circulatory system,Deep vein thrombosis,121,39,58,,,0,218,0.30,0.28,2.08,,0.38
2021-10-22,2021-10-29,Circulatory system,Embolism,3,3,7,,,0,13,0.01,0.02,0.25,,0.02
2021-10-22,2021-10-29,Circulatory system,Haemorrhage (bleeding),29,10,9,,,1,49,0.07,0.07,0.32,,0.09
2021-10-22,2021-10-29,Circulatory system,Pulmonary embolism,152,57,112,,,0,321,0.38,0.40,4.01,,0.56
2021-10-22,2021-10-29,Circulatory system,Thrombosis (blood clot),106,26,80,,,2,214,0.26,0.18,2.86,,0.37
2021-10-22,2021-10-29,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),16,6,61,,,0,83,0.04,0.04,2.18,,0.15
2021-10-22,2021-10-29,Circulatory system,Subtotal n (%),450,152,342,,,3,947,1.12,1.08,12.24,,1.65
2021-10-22,2021-10-29,Hepato-gastrointestinal and renal system,Acute kidney injury,20,14,3,,,0,37,0.05,0.10,0.11,,0.06
2021-10-22,2021-10-29,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),4,1,0,,,0,5,0.01,0.01,0.00,,0.01
2021-10-22,2021-10-29,Hepato-gastrointestinal and renal system,Liver injury,14,8,3,,,0,25,0.03,0.06,0.11,,0.04
2021-10-22,2021-10-29,Hepato-gastrointestinal and renal system,Subtotal n (%),38,23,6,,,0,67,0.09,0.16,0.21,,0.12
2021-10-22,2021-10-29,Nerves and central nervous system,Bell's Palsy/facial paralysis*,416,132,45,,,1,594,1.03,0.93,1.61,,1.04
2021-10-22,2021-10-29,Nerves and central nervous system,Cerebrovascular accident (stroke),87,31,34,,,3,155,0.22,0.22,1.22,,0.27
2021-10-22,2021-10-29,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),20,7,5,,,0,32,0.05,0.05,0.18,,0.06
2021-10-22,2021-10-29,Nerves and central nervous system,Subtotal n (%),523,170,84,,,4,781,1.30,0.42,0.21,,0.01
2021-10-22,2021-10-29,Other system,Anaphylaxis*,371,97,19,,,0,487,0.92,0.69,0.68,,0.85
2021-10-22,2021-10-29,Other system,COVID-19*,128,6,1,,,9,144,0.32,0.04,0.04,,0.25
2021-10-22,2021-10-29,Other system,Multisystem inflammatory syndrome,2,1,0,,,0,3,0.00,0.01,0.00,,0.01
2021-10-22,2021-10-29,Other system,Subtotal n (%),501,104,20,,,9,634,1.24,0.74,0.72,,1.11
2021-10-22,2021-10-29,Pregnancy outcomes,Fetal growth restriction,5,0,0,,,0,5,0.01,0.00,0.00,,0.01
2021-10-22,2021-10-29,Pregnancy outcomes,Spontaneous abortion,30,7,1,,,0,38,0.07,0.05,0.04,,0.07
2021-10-22,2021-10-29,Pregnancy outcomes,Subtotal n (%),35,7,1,,,0,43,0.09,0.05,0.04,,0.08
2021-10-22,2021-10-29,Respiratory system,Acute respiratory distress syndrome,2,1,0,,,0,3,0.00,0.01,0.00,,0.01
2021-10-22,2021-10-29,Respiratory system,Subtotal n (%),2,1,0,,,0,3,0.00,0.01,0.00,,0.01
2021-10-22,2021-10-29,"Skin and mucous membrane, bone and joints system",Chilblains,9,3,1,,,0,13,0.02,0.02,0.04,,0.02
2021-10-22,2021-10-29,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),17,10,1,,,0,28,0.04,0.07,0.04,,0.05
2021-10-22,2021-10-29,"Skin and mucous membrane, bone and joints system",Subtotal n (%),26,13,2,,,0,41,0.06,0.09,0.07,,0.07
2021-10-22,2021-10-29,All AESI categories,TOTAL,2307,897,561,,,28,3793,5.73,6.35,20.08,,6.63
2021-10-29,2021-11-05,Auto-immune diseases,Guillain-Barré Syndrome,41,21,35,,,0,97,0.10,0.15,1.25,,0.17
2021-10-29,2021-11-05,Auto-immune diseases,Thrombocytopenia (low blood platelets),21,10,38,,,3,72,0.05,0.07,1.36,,0.12
2021-10-29,2021-11-05,Auto-immune diseases,Subtotal n (%),62,31,73,,,3,169,0.15,0.22,2.61,,0.29
2021-10-29,2021-11-05,Cardiovascular system,Cardiac arrest,18,10,5,,,0,33,0.04,0.07,0.18,,0.06
2021-10-29,2021-11-05,Cardiovascular system,Cardiac failure,21,9,3,,,1,34,0.05,0.06,0.11,,0.06
2021-10-29,2021-11-05,Cardiovascular system,Myocardial infarction (heart attack),52,18,6,,,3,79,0.13,0.13,0.21,,0.14
2021-10-29,2021-11-05,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),613,374,21,,,4,1012,1.51,2.62,0.75,,1.75
2021-10-29,2021-11-05,Cardiovascular system,Subtotal n (%),704,411,35,,,8,1158,1.73,2.88,1.25,,2.01
2021-10-29,2021-11-05,Circulatory system,Cerebral venous (sinus) thrombosis,3,1,11,,,0,15,0.01,0.01,0.39,,0.03
2021-10-29,2021-11-05,Circulatory system,Cerebral thrombosis ,6,3,1,,,1,11,0.01,0.02,0.04,,0.02
2021-10-29,2021-11-05,Circulatory system,Cutaneous vasculitis,15,6,4,,,0,25,0.04,0.04,0.14,,0.04
2021-10-29,2021-11-05,Circulatory system,Deep vein thrombosis,124,40,59,,,0,223,0.31,0.28,2.11,,0.39
2021-10-29,2021-11-05,Circulatory system,Embolism,3,3,7,,,0,13,0.01,0.02,0.25,,0.02
2021-10-29,2021-11-05,Circulatory system,Haemorrhage (bleeding),30,10,9,,,2,51,0.07,0.07,0.32,,0.09
2021-10-29,2021-11-05,Circulatory system,Pulmonary embolism,154,57,114,,,0,325,0.38,0.40,4.08,,0.56
2021-10-29,2021-11-05,Circulatory system,Thrombosis (blood clot),114,26,82,,,2,224,0.28,0.18,2.93,,0.39
2021-10-29,2021-11-05,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),18,6,63,,,0,87,0.04,0.04,2.25,,0.15
2021-10-29,2021-11-05,Circulatory system,Subtotal n (%),467,152,350,,,5,974,1.15,1.07,12.52,,1.69
2021-10-29,2021-11-05,Hepato-gastrointestinal and renal system,Acute kidney injury,21,14,3,,,0,38,0.05,0.10,0.11,,0.07
2021-10-29,2021-11-05,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),6,1,0,,,0,7,0.01,0.01,0.00,,0.01
2021-10-29,2021-11-05,Hepato-gastrointestinal and renal system,Liver injury,15,8,3,,,0,26,0.04,0.06,0.11,,0.05
2021-10-29,2021-11-05,Hepato-gastrointestinal and renal system,Subtotal n (%),42,23,6,,,0,71,0.10,0.16,0.21,,0.12
2021-10-29,2021-11-05,Nerves and central nervous system,Bell's Palsy/facial paralysis*,427,138,45,,,1,611,1.05,0.97,1.61,,1.06
2021-10-29,2021-11-05,Nerves and central nervous system,Cerebrovascular accident (stroke),87,31,34,,,3,155,0.21,0.22,1.22,,0.27
2021-10-29,2021-11-05,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),20,8,5,,,0,33,0.05,0.06,0.18,,0.06
2021-10-29,2021-11-05,Nerves and central nervous system,Subtotal n (%),534,177,84,,,4,799,1.31,1.24,3.01,,1.38
2021-10-29,2021-11-05,Other system,Anaphylaxis*,406,111,21,,,1,539,1.00,0.78,0.75,,0.93
2021-10-29,2021-11-05,Other system,COVID-19*,130,6,1,,,10,147,0.32,0.04,0.04,,0.25
2021-10-29,2021-11-05,Other system,Multisystem inflammatory syndrome,3,1,0,,,0,4,0.01,0.01,0.00,,0.01
2021-10-29,2021-11-05,Other system,Subtotal n (%),539,118,22,,,11,690,1.33,0.83,0.79,,1.19
2021-10-29,2021-11-05,Pregnancy outcomes,Fetal growth restriction,5,0,0,,,0,5,0.01,0.00,0.00,,0.01
2021-10-29,2021-11-05,Pregnancy outcomes,Spontaneous abortion,32,7,1,,,0,40,0.08,0.05,0.04,,0.07
2021-10-29,2021-11-05,Pregnancy outcomes,Subtotal n (%),37,7,1,,,0,45,0.09,0.05,0.04,,0.08
2021-10-29,2021-11-05,Respiratory system,Acute respiratory distress syndrome,2,1,0,,,0,3,0.00,0.01,0.00,,0.01
2021-10-29,2021-11-05,Respiratory system,Subtotal n (%),2,1,0,,,0,3,0.00,0.01,0.00,,0.01
2021-10-29,2021-11-05,"Skin and mucous membrane, bone and joints system",Chilblains,9,3,1,,,0,13,0.02,0.02,0.04,,0.02
2021-10-29,2021-11-05,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),17,10,1,,,0,28,0.04,0.07,0.04,,0.05
2021-10-29,2021-11-05,"Skin and mucous membrane, bone and joints system",Subtotal n (%),26,13,2,,,0,41,0.06,0.09,0.07,,0.07
2021-10-29,2021-11-05,All AESI categories,TOTAL,2413,933,573,,,31,3950,5.94,6.55,20.50,,6.84
2021-11-05,2021-11-15,Auto-immune diseases,Guillain-Barré Syndrome,42,22,36,,,0,100,0.10,0.15,1.29,,0.17
2021-11-05,2021-11-15,Auto-immune diseases,Thrombocytopenia (low blood platelets),23,10,39,,,3,75,0.06,0.07,1.39,,0.13
2021-11-05,2021-11-15,Auto-immune diseases,Subtotal n (%),65,32,75,,,3,175,0.16,0.22,2.68,,0.30
2021-11-05,2021-11-15,Cardiovascular system,Cardiac arrest,18,10,5,,,0,33,0.04,0.07,0.18,,0.06
2021-11-05,2021-11-15,Cardiovascular system,Cardiac failure,21,9,3,,,1,34,0.05,0.06,0.11,,0.06
2021-11-05,2021-11-15,Cardiovascular system,Myocardial infarction (heart attack),53,20,6,,,3,82,0.13,0.14,0.21,,0.14
2021-11-05,2021-11-15,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),654,396,21,,,4,1075,1.60,2.76,0.75,,1.85
2021-11-05,2021-11-15,Cardiovascular system,Subtotal n (%),746,435,35,,,8,1224,1.82,3.03,1.25,,2.11
2021-11-05,2021-11-15,Circulatory system,Cerebral venous (sinus) thrombosis,3,1,11,,,0,15,0.01,0.01,0.39,,0.03
2021-11-05,2021-11-15,Circulatory system,Cerebral thrombosis ,6,3,1,,,1,11,0.01,0.02,0.04,,0.02
2021-11-05,2021-11-15,Circulatory system,Cutaneous vasculitis,15,7,4,,,0,26,0.04,0.05,0.14,,0.04
2021-11-05,2021-11-15,Circulatory system,Deep vein thrombosis,124,41,60,,,0,225,0.30,0.29,2.15,,0.39
2021-11-05,2021-11-15,Circulatory system,Embolism,3,3,7,,,0,13,0.01,0.02,0.25,,0.02
2021-11-05,2021-11-15,Circulatory system,Haemorrhage (bleeding),30,10,9,,,2,51,0.07,0.07,0.32,,0.09
2021-11-05,2021-11-15,Circulatory system,Pulmonary embolism,161,59,114,,,0,334,0.39,0.41,4.08,,0.57
2021-11-05,2021-11-15,Circulatory system,Thrombosis (blood clot),118,26,82,,,2,228,0.29,0.18,2.93,,0.39
2021-11-05,2021-11-15,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),19,6,63,,,0,88,0.05,0.04,2.25,,0.15
2021-11-05,2021-11-15,Circulatory system,Subtotal n (%),479,156,351,,,5,991,1.17,1.09,12.55,,1.70
2021-11-05,2021-11-15,Hepato-gastrointestinal and renal system,Acute kidney injury,22,14,3,,,0,39,0.05,0.10,0.11,,0.07
2021-11-05,2021-11-15,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),6,1,0,,,0,7,0.01,0.01,0.00,,0.01
2021-11-05,2021-11-15,Hepato-gastrointestinal and renal system,Liver injury,16,8,3,,,0,27,0.04,0.06,0.11,,0.05
2021-11-05,2021-11-15,Hepato-gastrointestinal and renal system,Subtotal n (%),44,23,6,,,0,73,0.11,0.16,0.21,,0.13
2021-11-05,2021-11-15,Nerves and central nervous system,Bell's Palsy/facial paralysis*,440,139,45,,,1,625,1.07,0.97,1.61,,1.08
2021-11-05,2021-11-15,Nerves and central nervous system,Cerebrovascular accident (stroke),87,33,34,,,3,157,0.21,0.23,1.22,,0.27
2021-11-05,2021-11-15,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),21,8,5,,,0,34,0.05,0.06,0.18,,0.06
2021-11-05,2021-11-15,Nerves and central nervous system,Subtotal n (%),548,180,84,,,4,816,1.34,1.25,3.00,,1.40
2021-11-05,2021-11-15,Other system,Anaphylaxis*,441,125,21,,,1,588,1.08,0.87,0.75,,1.01
2021-11-05,2021-11-15,Other system,COVID-19*,133,6,1,,,10,150,0.32,0.04,0.04,,0.26
2021-11-05,2021-11-15,Other system,Multisystem inflammatory syndrome,4,1,0,,,0,5,0.01,0.01,0.00,,0.01
2021-11-05,2021-11-15,Other system,Subtotal n (%),578,132,22,,,11,743,1.41,0.92,0.79,,1.28
2021-11-05,2021-11-15,Pregnancy outcomes,Fetal growth restriction,5,0,0,,,0,5,0.01,0.00,0.00,,0.01
2021-11-05,2021-11-15,Pregnancy outcomes,Spontaneous abortion,34,9,1,,,0,44,0.08,0.06,0.04,,0.08
2021-11-05,2021-11-15,Pregnancy outcomes,Subtotal n (%),39,9,1,,,0,49,0.10,0.06,0.04,,0.08
2021-11-05,2021-11-15,Respiratory system,Acute respiratory distress syndrome,2,1,0,,,0,3,0.00,0.01,0.00,,0.01
2021-11-05,2021-11-15,Respiratory system,Subtotal n (%),2,1,0,,,0,3,0.00,0.01,0.00,,0.01
2021-11-05,2021-11-15,"Skin and mucous membrane, bone and joints system",Chilblains,10,3,1,,,0,14,0.02,0.02,0.04,,0.02
2021-11-05,2021-11-15,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),18,10,1,,,0,29,0.04,0.07,0.04,,0.05
2021-11-05,2021-11-15,"Skin and mucous membrane, bone and joints system",Subtotal n (%),28,13,2,,,0,43,0.07,0.09,0.07,,0.07
2021-11-05,2021-11-15,All AESI categories,TOTAL,2529,981,576,,,31,4117,6.18,6.83,20.60,,7.08
2021-11-12,2021-11-19,Auto-immune diseases,Guillain-Barré Syndrome,44,22,37,,,0,103,0.11,0.15,1.32,,0.18
2021-11-12,2021-11-19,Auto-immune diseases,Thrombocytopenia (low blood platelets),21,10,39,,,3,73,0.05,0.07,1.39,,0.12
2021-11-12,2021-11-19,Auto-immune diseases,Subtotal n (%),65,32,76,,,3,176,0.16,0.22,2.72,,0.30
2021-11-12,2021-11-19,Cardiovascular system,Cardiac arrest,18,10,5,,,0,33,0.04,0.07,0.18,,0.06
2021-11-12,2021-11-19,Cardiovascular system,Cardiac failure,21,9,4,,,1,35,0.05,0.06,0.14,,0.06
2021-11-12,2021-11-19,Cardiovascular system,Myocardial infarction (heart attack),55,20,6,,,3,84,0.13,0.14,0.21,,0.14
2021-11-12,2021-11-19,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),775,439,24,,,3,1241,1.88,3.03,0.86,,2.12
2021-11-12,2021-11-19,Cardiovascular system,Subtotal n (%),869,478,39,,,7,1393,2.10,3.30,1.39,,2.38
2021-11-12,2021-11-19,Circulatory system,Cerebral venous (sinus) thrombosis,3,1,11,,,0,15,0.01,0.01,0.39,,0.03
2021-11-12,2021-11-19,Circulatory system,Cerebral thrombosis ,5,4,1,,,1,11,0.01,0.03,0.04,,0.02
2021-11-12,2021-11-19,Circulatory system,Cutaneous vasculitis,16,7,4,,,0,27,0.04,0.05,0.14,,0.05
2021-11-12,2021-11-19,Circulatory system,Deep vein thrombosis,126,44,61,,,0,231,0.30,0.30,2.18,,0.39
2021-11-12,2021-11-19,Circulatory system,Embolism,3,3,7,,,0,13,0.01,0.02,0.25,,0.02
2021-11-12,2021-11-19,Circulatory system,Haemorrhage (bleeding),31,11,8,,,2,52,0.08,0.08,0.29,,0.09
2021-11-12,2021-11-19,Circulatory system,Pulmonary embolism,170,62,117,,,0,349,0.41,0.43,4.18,,0.60
2021-11-12,2021-11-19,Circulatory system,Thrombosis (blood clot),119,27,86,,,2,234,0.29,0.19,3.08,,0.40
2021-11-12,2021-11-19,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),19,6,64,,,0,89,0.05,0.04,2.29,,0.15
2021-11-12,2021-11-19,Circulatory system,Subtotal n (%),492,165,359,,,5,1021,1.19,1.14,12.84,,1.74
2021-11-12,2021-11-19,Hepato-gastrointestinal and renal system,Acute kidney injury,23,14,4,,,0,41,0.06,0.10,0.14,,0.07
2021-11-12,2021-11-19,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),6,1,0,,,0,7,0.01,0.01,0.00,,0.01
2021-11-12,2021-11-19,Hepato-gastrointestinal and renal system,Liver injury,17,8,3,,,0,28,0.04,0.06,0.11,,0.05
2021-11-12,2021-11-19,Hepato-gastrointestinal and renal system,Subtotal n (%),46,23,7,,,0,76,0.11,0.16,0.25,,0.13
2021-11-12,2021-11-19,Nerves and central nervous system,Bell's Palsy/facial paralysis*,453,148,47,,,1,649,1.10,1.02,1.68,,1.11
2021-11-12,2021-11-19,Nerves and central nervous system,Cerebrovascular accident (stroke),91,32,34,,,3,160,0.22,0.22,1.22,,0.27
2021-11-12,2021-11-19,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),22,8,5,,,0,35,0.05,0.06,0.18,,0.06
2021-11-12,2021-11-19,Nerves and central nervous system,Subtotal n (%),566,188,86,,,4,844,1.37,1.30,3.08,,1.44
2021-11-12,2021-11-19,Other system,Anaphylaxis*,464,128,22,,,1,615,1.12,0.88,0.79,,1.05
2021-11-12,2021-11-19,Other system,COVID-19*,137,7,1,,,10,155,0.33,0.05,0.04,,0.26
2021-11-12,2021-11-19,Other system,Multisystem inflammatory syndrome,4,1,0,,,0,5,0.01,0.01,0.00,,0.01
2021-11-12,2021-11-19,Other system,Subtotal n (%),605,136,23,,,11,775,1.46,0.94,0.82,,1.32
2021-11-12,2021-11-19,Pregnancy outcomes,Fetal growth restriction,5,0,0,,,0,5,0.01,0.00,0.00,,0.01
2021-11-12,2021-11-19,Pregnancy outcomes,Spontaneous abortion,42,9,1,,,0,52,0.10,0.06,0.04,,0.09
2021-11-12,2021-11-19,Pregnancy outcomes,Subtotal n (%),47,9,1,,,0,57,0.11,0.06,0.04,,0.10
2021-11-12,2021-11-19,Respiratory system,Acute respiratory distress syndrome,2,2,0,,,0,4,0.00,0.01,0.00,,0.01
2021-11-12,2021-11-19,Respiratory system,Subtotal n (%),2,2,0,,,0,4,0.00,0.01,0.00,,0.01
2021-11-12,2021-11-19,"Skin and mucous membrane, bone and joints system",Chilblains,10,3,1,,,0,14,0.02,0.02,0.04,,0.02
2021-11-12,2021-11-19,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),19,10,1,,,0,30,0.05,0.07,0.04,,0.05
2021-11-12,2021-11-19,"Skin and mucous membrane, bone and joints system",Subtotal n (%),29,13,2,,,0,44,0.07,0.09,0.07,,0.08
2021-11-12,2021-11-19,All AESI categories,TOTAL,2721,1046,593,,,30,4390,6.59,7.23,21.20,,7.49
2021-11-19,2021-11-26,Auto-immune diseases,Guillain-Barré Syndrome,44,22,37,,,0,103,0.11,0.15,1.32,,0.17
2021-11-19,2021-11-26,Auto-immune diseases,Thrombocytopenia (low blood platelets),23,10,40,,,3,76,0.06,0.07,1.43,,0.13
2021-11-19,2021-11-26,Auto-immune diseases,Subtotal n (%),67,32,77,,,3,179,0.16,0.22,2.75,,0.30
2021-11-19,2021-11-26,Cardiovascular system,Cardiac arrest,19,12,5,,,0,36,0.05,0.08,0.18,,0.06
2021-11-19,2021-11-26,Cardiovascular system,Cardiac failure,22,9,4,,,1,36,0.05,0.06,0.14,,0.06
2021-11-19,2021-11-26,Cardiovascular system,Myocardial infarction (heart attack),61,20,6,,,3,90,0.15,0.14,0.21,,0.15
2021-11-19,2021-11-26,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),823,479,24,,,3,1329,1.98,3.27,0.86,,2.25
2021-11-19,2021-11-26,Cardiovascular system,Subtotal n (%),925,520,39,,,7,1491,2.22,3.55,1.39,,2.52
2021-11-19,2021-11-26,Circulatory system,Cerebral venous (sinus) thrombosis,3,1,11,,,0,15,0.01,0.01,0.39,,0.03
2021-11-19,2021-11-26,Circulatory system,Cerebral thrombosis ,6,4,1,,,0,11,0.01,0.03,0.04,,0.02
2021-11-19,2021-11-26,Circulatory system,Cutaneous vasculitis,16,7,4,,,0,27,0.04,0.05,0.14,,0.05
2021-11-19,2021-11-26,Circulatory system,Deep vein thrombosis,127,44,61,,,0,232,0.30,0.30,2.18,,0.39
2021-11-19,2021-11-26,Circulatory system,Embolism,3,3,6,,,0,12,0.01,0.02,0.21,,0.02
2021-11-19,2021-11-26,Circulatory system,Haemorrhage (bleeding),31,10,8,,,2,51,0.07,0.07,0.29,,0.09
2021-11-19,2021-11-26,Circulatory system,Pulmonary embolism,173,65,116,,,0,354,0.42,0.44,4.15,,0.60
2021-11-19,2021-11-26,Circulatory system,Thrombosis (blood clot),120,27,85,,,2,234,0.29,0.18,3.04,,0.40
2021-11-19,2021-11-26,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),19,6,64,,,0,89,0.05,0.04,2.29,,0.15
2021-11-19,2021-11-26,Circulatory system,Subtotal n (%),498,167,356,,,4,1025,1.20,1.14,12.73,,1.73
2021-11-19,2021-11-26,Hepato-gastrointestinal and renal system,Acute kidney injury,23,14,4,,,0,41,0.06,0.10,0.14,,0.07
2021-11-19,2021-11-26,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),6,2,0,,,0,8,0.01,0.01,0.00,,0.01
2021-11-19,2021-11-26,Hepato-gastrointestinal and renal system,Liver injury,16,8,3,,,0,27,0.04,0.05,0.11,,0.05
2021-11-19,2021-11-26,Hepato-gastrointestinal and renal system,Subtotal n (%),45,24,7,,,0,76,0.11,0.16,0.25,,0.13
2021-11-19,2021-11-26,Nerves and central nervous system,Bell's Palsy/facial paralysis*,455,150,47,,,1,653,1.09,1.02,1.68,,1.10
2021-11-19,2021-11-26,Nerves and central nervous system,Cerebrovascular accident (stroke),96,33,34,,,3,166,0.23,0.23,1.22,,0.28
2021-11-19,2021-11-26,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),23,8,5,,,0,36,0.06,0.05,0.18,,0.06
2021-11-19,2021-11-26,Nerves and central nervous system,Subtotal n (%),574,191,86,,,4,855,1.38,1.30,3.07,,1.45
2021-11-19,2021-11-26,Other system,Anaphylaxis*,488,131,23,,,1,643,1.17,0.89,0.82,,1.09
2021-11-19,2021-11-26,Other system,COVID-19*,138,6,1,,,11,156,0.33,0.04,0.04,,0.26
2021-11-19,2021-11-26,Other system,Multisystem inflammatory syndrome,4,1,0,,,0,5,0.01,0.01,0.00,,0.01
2021-11-19,2021-11-26,Other system,Subtotal n (%),630,138,24,,,12,804,1.51,0.94,0.86,,1.36
2021-11-19,2021-11-26,Pregnancy outcomes,Fetal growth restriction,5,0,0,,,0,5,0.01,0.00,0.00,,0.01
2021-11-19,2021-11-26,Pregnancy outcomes,Spontaneous abortion,43,10,1,,,0,54,0.10,0.07,0.04,,0.09
2021-11-19,2021-11-26,Pregnancy outcomes,Subtotal n (%),48,10,1,,,0,59,0.12,0.07,0.04,,0.10
2021-11-19,2021-11-26,Respiratory system,Acute respiratory distress syndrome,2,2,0,,,0,4,0.00,0.01,0.00,,0.01
2021-11-19,2021-11-26,Respiratory system,Subtotal n (%),2,2,0,,,0,4,0.00,0.01,0.00,,0.01
2021-11-19,2021-11-26,"Skin and mucous membrane, bone and joints system",Chilblains,11,3,1,,,0,15,0.03,0.02,0.04,,0.03
2021-11-19,2021-11-26,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),20,10,1,,,0,31,0.05,0.07,0.04,,0.05
2021-11-19,2021-11-26,"Skin and mucous membrane, bone and joints system",Subtotal n (%),31,13,2,,,0,46,0.07,0.09,0.07,,0.08
2021-11-19,2021-11-26,All AESI categories,TOTAL,2820,1097,592,,,30,4539,6.77,7.49,21.16,,7.67
2021-11-26,2021-12-03,Auto-immune diseases,Guillain-Barré Syndrome,44,22,37,,,0,103,0.10,0.15,1.32,,0.17
2021-11-26,2021-12-03,Auto-immune diseases,Thrombocytopenia (low blood platelets),19,9,40,,,3,71,0.05,0.06,1.43,,0.12
2021-11-26,2021-12-03,Auto-immune diseases,Subtotal n (%),63,31,77,,,3,174,0.15,0.21,2.75,,0.29
2021-11-26,2021-12-03,Cardiovascular system,Cardiac arrest,19,12,5,,,0,36,0.05,0.08,0.18,,0.06
2021-11-26,2021-12-03,Cardiovascular system,Cardiac failure,23,9,4,,,1,37,0.05,0.06,0.14,,0.06
2021-11-26,2021-12-03,Cardiovascular system,Myocardial infarction (heart attack),65,20,6,,,3,94,0.15,0.14,0.21,,0.16
2021-11-26,2021-12-03,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),853,495,25,,,3,1376,2.03,3.37,0.89,,2.31
2021-11-26,2021-12-03,Cardiovascular system,Subtotal n (%),960,536,40,,,7,1543,2.28,3.64,1.43,,2.59
2021-11-26,2021-12-03,Circulatory system,Cerebral venous (sinus) thrombosis,4,1,12,,,0,17,0.01,0.01,0.43,,0.03
2021-11-26,2021-12-03,Circulatory system,Cerebral thrombosis,6,4,1,,,0,11,0.01,0.03,0.04,,0.02
2021-11-26,2021-12-03,Circulatory system,Cutaneous vasculitis,14,8,6,,,0,28,0.03,0.05,0.21,,0.05
2021-11-26,2021-12-03,Circulatory system,Deep vein thrombosis,132,45,61,,,0,238,0.31,0.31,2.18,,0.40
2021-11-26,2021-12-03,Circulatory system,Embolism,3,3,6,,,0,12,0.01,0.02,0.21,,0.02
2021-11-26,2021-12-03,Circulatory system,Haemorrhage (bleeding),31,11,8,,,2,52,0.07,0.07,0.29,,0.09
2021-11-26,2021-12-03,Circulatory system,Pulmonary embolism,177,66,116,,,0,359,0.42,0.45,4.15,,0.60
2021-11-26,2021-12-03,Circulatory system,Thrombosis (blood clot),125,27,85,,,2,239,0.30,0.18,3.04,,0.40
2021-11-26,2021-12-03,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),19,6,64,,,0,89,0.05,0.04,2.29,,0.15
2021-11-26,2021-12-03,Circulatory system,Subtotal n (%),511,171,359,,,4,1045,1.22,1.16,12.83,,1.75
2021-11-26,2021-12-03,Hepato-gastrointestinal and renal system,Acute kidney injury,24,14,4,,,0,42,0.06,0.10,0.14,,0.07
2021-11-26,2021-12-03,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),6,2,0,,,0,8,0.01,0.01,0.00,,0.01
2021-11-26,2021-12-03,Hepato-gastrointestinal and renal system,Liver injury,16,8,3,,,0,27,0.04,0.05,0.11,,0.05
2021-11-26,2021-12-03,Hepato-gastrointestinal and renal system,Subtotal n (%),46,24,7,,,0,77,0.11,0.16,0.25,,0.13
2021-11-26,2021-12-03,Nerves and central nervous system,Bell's Palsy/facial paralysis*,462,152,48,,,1,663,1.10,1.03,1.72,,1.11
2021-11-26,2021-12-03,Nerves and central nervous system,Cerebrovascular accident (stroke),98,35,34,,,3,170,0.23,0.24,1.22,,0.29
2021-11-26,2021-12-03,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),24,7,5,,,0,36,0.06,0.05,0.18,,0.06
2021-11-26,2021-12-03,Nerves and central nervous system,Subtotal n (%),584,194,87,,,4,869,1.39,1.32,3.11,,1.46
2021-11-26,2021-12-03,Other system,Anaphylaxis*,505,141,24,,,1,671,1.20,0.96,0.86,,1.13
2021-11-26,2021-12-03,Other system,COVID-19*,141,7,1,,,11,160,0.34,0.05,0.04,,0.27
2021-11-26,2021-12-03,Other system,Multisystem inflammatory syndrome,4,1,0,,,0,5,0.01,0.01,0.00,,0.01
2021-11-26,2021-12-03,Other system,Subtotal n (%),650,149,25,,,12,836,1.55,1.01,0.89,,1.40
2021-11-26,2021-12-03,Pregnancy outcomes,Fetal growth restriction,5,0,0,,,0,5,0.01,0.00,0.00,,0.01
2021-11-26,2021-12-03,Pregnancy outcomes,Spontaneous abortion,45,10,1,,,0,56,0.11,0.07,0.04,,0.09
2021-11-26,2021-12-03,Pregnancy outcomes,Subtotal n (%),50,10,1,,,0,61,0.12,0.07,0.04,,0.10
2021-11-26,2021-12-03,Respiratory system,Acute respiratory distress syndrome,2,2,0,,,0,4,0.00,0.01,0.00,,0.01
2021-11-26,2021-12-03,Respiratory system,Subtotal n (%),2,2,0,,,0,4,0.00,0.01,0.00,,0.01
2021-11-26,2021-12-03,"Skin and mucous membrane, bone and joints system",Chilblains,11,3,1,,,0,15,0.03,0.02,0.04,,0.03
2021-11-26,2021-12-03,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),21,10,1,,,0,32,0.05,0.07,0.04,,0.05
2021-11-26,2021-12-03,"Skin and mucous membrane, bone and joints system",Subtotal n (%),32,13,2,,,0,47,0.08,0.09,0.07,,0.08
2021-11-26,2021-12-03,All AESI categories,TOTAL,2898,1130,598,,,30,4656,6.89,7.68,21.37,,7.81
2021-12-03,2021-12-10,Auto-immune diseases,Guillain-Barré Syndrome,47,22,37,,,0,106,0.11,0.15,1.32,,0.18
2021-12-03,2021-12-10,Auto-immune diseases,Thrombocytopenia (low blood platelets),19,9,39,,,3,70,0.05,0.06,1.39,,0.12
2021-12-03,2021-12-10,Auto-immune diseases,Subtotal n (%),66,31,76,,,3,176,0.16,0.21,2.72,,0.30
2021-12-03,2021-12-10,Cardiovascular system,Cardiac arrest,20,13,6,,,0,39,0.05,0.09,0.21,,0.07
2021-12-03,2021-12-10,Cardiovascular system,Cardiac failure,23,10,4,,,1,38,0.05,0.07,0.14,,0.06
2021-12-03,2021-12-10,Cardiovascular system,Myocardial infarction (heart attack),64,20,6,,,3,93,0.15,0.14,0.21,,0.16
2021-12-03,2021-12-10,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),887,510,27,,,4,1428,2.11,3.47,0.96,,2.40
2021-12-03,2021-12-10,Cardiovascular system,Subtotal n (%),994,553,43,,,8,1598,2.36,3.76,1.54,,2.68
2021-12-03,2021-12-10,Circulatory system,Cerebral venous (sinus) thrombosis,4,1,11,,,0,16,0.01,0.01,0.39,,0.03
2021-12-03,2021-12-10,Circulatory system,Cerebral thrombosis ,6,4,1,,,0,11,0.01,0.03,0.04,,0.02
2021-12-03,2021-12-10,Circulatory system,Cutaneous vasculitis,15,8,7,,,0,30,0.04,0.05,0.25,,0.05
2021-12-03,2021-12-10,Circulatory system,Deep vein thrombosis,131,47,63,,,0,241,0.31,0.32,2.25,,0.40
2021-12-03,2021-12-10,Circulatory system,Embolism,4,3,6,,,0,13,0.01,0.02,0.21,,0.02
2021-12-03,2021-12-10,Circulatory system,Haemorrhage (bleeding),31,11,8,,,2,52,0.07,0.07,0.29,,0.09
2021-12-03,2021-12-10,Circulatory system,Pulmonary embolism,181,66,117,,,0,364,0.43,0.45,4.18,,0.61
2021-12-03,2021-12-10,Circulatory system,Thrombosis (blood clot),135,29,86,,,2,252,0.32,0.20,3.07,,0.42
2021-12-03,2021-12-10,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),19,6,64,,,0,89,0.05,0.04,2.29,,0.15
2021-12-03,2021-12-10,Circulatory system,Subtotal n (%),526,175,363,,,4,1068,1.25,1.19,12.97,,1.79
2021-12-03,2021-12-10,Hepato-gastrointestinal and renal system,Acute kidney injury,25,14,5,,,0,44,0.06,0.10,0.18,,0.07
2021-12-03,2021-12-10,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),7,2,1,,,0,10,0.02,0.01,0.04,,0.02
2021-12-03,2021-12-10,Hepato-gastrointestinal and renal system,Liver injury,17,8,3,,,0,28,0.04,0.05,0.11,,0.05
2021-12-03,2021-12-10,Hepato-gastrointestinal and renal system,Subtotal n (%),49,24,9,,,0,82,0.12,0.16,0.32,,0.14
2021-12-03,2021-12-10,Nerves and central nervous system,Bell's Palsy/facial paralysis*,476,154,48,,,1,679,1.13,1.05,1.72,,1.14
2021-12-03,2021-12-10,Nerves and central nervous system,Cerebrovascular accident (stroke),98,36,34,,,3,171,0.23,0.24,1.22,,0.29
2021-12-03,2021-12-10,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),25,8,5,,,0,38,0.06,0.05,0.18,,0.06
2021-12-03,2021-12-10,Nerves and central nervous system,Subtotal n (%),599,198,87,,,4,888,1.43,1.35,3.11,,1.49
2021-12-03,2021-12-10,Other system,Anaphylaxis*,514,143,25,,,1,683,1.22,0.97,0.89,,1.15
2021-12-03,2021-12-10,Other system,COVID-19*,143,7,1,,,12,163,0.34,0.05,0.04,,0.27
2021-12-03,2021-12-10,Other system,Multisystem inflammatory syndrome,5,1,0,,,0,6,0.01,0.01,0.00,,0.01
2021-12-03,2021-12-10,Other system,Subtotal n (%),662,151,26,,,13,852,1.57,1.03,0.93,,1.43
2021-12-03,2021-12-10,Pregnancy outcomes,Fetal growth restriction,5,0,0,,,0,5,0.01,0.00,0.00,,0.01
2021-12-03,2021-12-10,Pregnancy outcomes,Spontaneous abortion,46,10,1,,,0,57,0.11,0.07,0.04,,0.10
2021-12-03,2021-12-10,Pregnancy outcomes,Subtotal n (%),51,10,1,,,0,62,0.12,0.07,0.04,,0.10
2021-12-03,2021-12-10,Respiratory system,Acute respiratory distress syndrome,2,2,0,,,0,4,0.00,0.01,0.00,,0.01
2021-12-03,2021-12-10,Respiratory system,Subtotal n (%),2,2,0,,,0,4,0.00,0.01,0.00,,0.01
2021-12-03,2021-12-10,"Skin and mucous membrane, bone and joints system",Chilblains,11,4,1,,,0,16,0.03,0.03,0.04,,0.03
2021-12-03,2021-12-10,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),22,10,1,,,0,33,0.05,0.07,0.04,,0.06
2021-12-03,2021-12-10,"Skin and mucous membrane, bone and joints system",Subtotal n (%),33,14,2,,,0,49,0.08,0.10,0.07,,0.08
2021-12-03,2021-12-10,All AESI categories,TOTAL,2982,1158,607,,,32,4779,7.09,7.87,21.69,,8.02
2021-12-10,2021-12-17,Auto-immune diseases,Guillain-Barré Syndrome,49,22,38,,,0,109,0.12,0.15,1.36,,0.18
2021-12-10,2021-12-17,Auto-immune diseases,Thrombocytopenia (low blood platelets),19,9,39,,,3,70,0.05,0.06,1.39,,0.12
2021-12-10,2021-12-17,Auto-immune diseases,Subtotal n (%),68,31,77,,,3,179,0.16,0.21,2.75,,0.30
2021-12-10,2021-12-17,Cardiovascular system,Cardiac arrest,20,13,6,,,0,39,0.05,0.09,0.21,,0.07
2021-12-10,2021-12-17,Cardiovascular system,Cardiac failure,23,10,4,,,1,38,0.05,0.07,0.14,,0.06
2021-12-10,2021-12-17,Cardiovascular system,Myocardial infarction (heart attack),66,21,6,,,3,96,0.16,0.14,0.21,,0.16
2021-12-10,2021-12-17,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),913,519,27,,,4,1463,2.17,3.53,0.96,,2.45
2021-12-10,2021-12-17,Cardiovascular system,Subtotal n (%),1022,563,43,,,8,1636,2.43,3.83,1.54,,2.75
2021-12-10,2021-12-17,Circulatory system,Cerebral venous (sinus) thrombosis,4,1,11,,,0,16,0.01,0.01,0.39,,0.03
2021-12-10,2021-12-17,Circulatory system,Cerebral thrombosis ,6,4,1,,,0,11,0.01,0.03,0.04,,0.02
2021-12-10,2021-12-17,Circulatory system,Cutaneous vasculitis,15,8,7,,,0,30,0.04,0.05,0.25,,0.05
2021-12-10,2021-12-17,Circulatory system,Deep vein thrombosis,134,49,63,,,0,246,0.32,0.33,2.25,,0.41
2021-12-10,2021-12-17,Circulatory system,Embolism,4,4,6,,,0,14,0.01,0.03,0.21,,0.02
2021-12-10,2021-12-17,Circulatory system,Haemorrhage (bleeding),31,12,8,,,2,53,0.07,0.08,0.29,,0.09
2021-12-10,2021-12-17,Circulatory system,Pulmonary embolism,185,67,118,,,0,370,0.44,0.46,4.22,,0.62
2021-12-10,2021-12-17,Circulatory system,Thrombosis (blood clot),135,30,87,,,2,254,0.32,0.20,3.11,,0.43
2021-12-10,2021-12-17,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),19,6,64,,,0,89,0.05,0.04,2.29,,0.15
2021-12-10,2021-12-17,Circulatory system,Subtotal n (%),533,181,365,,,4,1083,1.27,1.23,13.04,,1.82
2021-12-10,2021-12-17,Hepato-gastrointestinal and renal system,Acute kidney injury,27,14,5,,,0,46,0.06,0.10,0.18,,0.08
2021-12-10,2021-12-17,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),7,2,1,,,0,10,0.02,0.01,0.04,,0.02
2021-12-10,2021-12-17,Hepato-gastrointestinal and renal system,Liver injury,19,8,3,,,0,30,0.05,0.05,0.11,,0.05
2021-12-10,2021-12-17,Hepato-gastrointestinal and renal system,Subtotal n (%),53,24,9,,,0,86,0.13,0.16,0.32,,0.14
2021-12-10,2021-12-17,Nerves and central nervous system,Bell's Palsy/facial paralysis*,485,155,48,,,1,689,1.15,1.05,1.72,,1.16
2021-12-10,2021-12-17,Nerves and central nervous system,Cerebrovascular accident (stroke),101,37,35,,,3,176,0.24,0.25,1.25,,0.30
2021-12-10,2021-12-17,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),25,8,5,,,0,38,0.06,0.05,0.18,,0.06
2021-12-10,2021-12-17,Nerves and central nervous system,Subtotal n (%),611,200,88,,,4,903,1.45,1.36,3.14,,1.52
2021-12-10,2021-12-17,Other system,Anaphylaxis*,524,145,25,,,1,695,1.25,0.99,0.89,,1.17
2021-12-10,2021-12-17,Other system,COVID-19*,147,8,1,,,12,168,0.35,0.05,0.04,,0.28
2021-12-10,2021-12-17,Other system,Multisystem inflammatory syndrome,6,1,0,,,0,7,0.01,0.01,0.00,,0.01
2021-12-10,2021-12-17,Other system,Subtotal n (%),677,154,26,,,13,870,1.61,1.05,0.93,,1.46
2021-12-10,2021-12-17,Pregnancy outcomes,Fetal growth restriction,5,0,0,,,0,5,0.01,0.00,0.00,,0.01
2021-12-10,2021-12-17,Pregnancy outcomes,Spontaneous abortion,49,11,1,,,0,61,0.12,0.07,0.04,,0.10
2021-12-10,2021-12-17,Pregnancy outcomes,Subtotal n (%),54,11,1,,,0,66,0.13,0.07,0.04,,0.11
2021-12-10,2021-12-17,Respiratory system,Acute respiratory distress syndrome,3,2,0,,,0,5,0.01,0.01,0.00,,0.01
2021-12-10,2021-12-17,Respiratory system,Subtotal n (%),3,2,0,,,0,5,0.01,0.01,0.00,,0.01
2021-12-10,2021-12-17,"Skin and mucous membrane, bone and joints system",Chilblains,11,5,1,,,0,17,0.03,0.03,0.04,,0.03
2021-12-10,2021-12-17,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),22,12,1,,,0,35,0.05,0.08,0.04,,0.06
2021-12-10,2021-12-17,"Skin and mucous membrane, bone and joints system",Subtotal n (%),33,17,2,,,0,52,0.08,0.12,0.07,,0.09
2021-12-10,2021-12-17,All AESI categories,TOTAL,3054,1183,611,,,32,4880,7.27,8.04,21.83,,8.19
2021-12-17,2021-12-24,Auto-immune diseases,Guillain-Barré Syndrome,50,22,39,,,0,111,0.12,0.15,1.39,,0.19
2021-12-17,2021-12-24,Auto-immune diseases,Thrombocytopenia (low blood platelets),19,9,39,,,3,70,0.05,0.06,1.39,,0.12
2021-12-17,2021-12-24,Auto-immune diseases,Subtotal n (%),69,31,78,,,3,181,0.16,0.21,2.79,,0.30
2021-12-17,2021-12-24,Cardiovascular system,Cardiac arrest,20,13,6,,,0,39,0.05,0.09,0.21,,0.07
2021-12-17,2021-12-24,Cardiovascular system,Cardiac failure,23,10,4,,,1,38,0.05,0.07,0.14,,0.06
2021-12-17,2021-12-24,Cardiovascular system,Myocardial infarction (heart attack),67,21,7,,,3,98,0.16,0.14,0.25,,0.16
2021-12-17,2021-12-24,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),951,532,28,,,5,1516,2.26,3.62,1.00,,2.54
2021-12-17,2021-12-24,Cardiovascular system,Subtotal n (%),1061,576,45,,,9,1691,2.52,3.92,1.61,,2.84
2021-12-17,2021-12-24,Circulatory system,Cerebral venous (sinus) thrombosis,4,1,11,,,0,16,0.01,0.01,0.39,,0.03
2021-12-17,2021-12-24,Circulatory system,Cerebral thrombosis ,6,4,1,,,0,11,0.01,0.03,0.04,,0.02
2021-12-17,2021-12-24,Circulatory system,Cutaneous vasculitis,15,8,7,,,0,30,0.04,0.05,0.25,,0.05
2021-12-17,2021-12-24,Circulatory system,Deep vein thrombosis,135,50,63,,,0,248,0.32,0.34,2.25,,0.42
2021-12-17,2021-12-24,Circulatory system,Embolism,5,4,6,,,0,15,0.01,0.03,0.21,,0.03
2021-12-17,2021-12-24,Circulatory system,Haemorrhage (bleeding),32,12,8,,,2,54,0.08,0.08,0.29,,0.09
2021-12-17,2021-12-24,Circulatory system,Pulmonary embolism,188,69,118,,,0,375,0.45,0.47,4.22,,0.63
2021-12-17,2021-12-24,Circulatory system,Thrombosis (blood clot),139,31,87,,,2,259,0.33,0.21,3.11,,0.43
2021-12-17,2021-12-24,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),19,6,64,,,0,89,0.05,0.04,2.29,,0.15
2021-12-17,2021-12-24,Circulatory system,Subtotal n (%),543,185,365,,,4,1097,1.29,1.26,13.04,,1.84
2021-12-17,2021-12-24,Hepato-gastrointestinal and renal system,Acute kidney injury,27,14,5,,,0,46,0.06,0.10,0.18,,0.08
2021-12-17,2021-12-24,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),7,3,1,,,0,11,0.02,0.02,0.04,,0.02
2021-12-17,2021-12-24,Hepato-gastrointestinal and renal system,Liver injury,19,8,3,,,0,30,0.05,0.05,0.11,,0.05
2021-12-17,2021-12-24,Hepato-gastrointestinal and renal system,Subtotal n (%),53,25,9,,,0,87,0.13,0.17,0.32,,0.15
2021-12-17,2021-12-24,Nerves and central nervous system,Bell's Palsy/facial paralysis*,490,155,48,,,1,694,1.17,1.05,1.72,,1.16
2021-12-17,2021-12-24,Nerves and central nervous system,Cerebrovascular accident (stroke),103,38,35,,,3,179,0.25,0.26,1.25,,0.30
2021-12-17,2021-12-24,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),26,9,5,,,0,40,0.06,0.06,0.18,,0.07
2021-12-17,2021-12-24,Nerves and central nervous system,Subtotal n (%),619,202,88,,,4,913,1.47,1.37,3.14,,1.53
2021-12-17,2021-12-24,Other system,Anaphylaxis*,532,147,25,,,1,705,1.27,1.00,0.89,,1.18
2021-12-17,2021-12-24,Other system,COVID-19*,149,8,1,,,12,170,0.35,0.05,0.04,,0.29
2021-12-17,2021-12-24,Other system,Multisystem inflammatory syndrome,6,1,0,,,0,7,0.01,0.01,0.00,,0.01
2021-12-17,2021-12-24,Other system,Subtotal n (%),687,156,26,,,13,882,1.63,1.06,0.93,,1.48
2021-12-17,2021-12-24,Pregnancy outcomes,Fetal growth restriction,5,0,0,,,0,5,0.01,0.00,0.00,,0.01
2021-12-17,2021-12-24,Pregnancy outcomes,Spontaneous abortion,49,11,1,,,0,61,0.12,0.07,0.04,,0.10
2021-12-17,2021-12-24,Pregnancy outcomes,Subtotal n (%),54,11,1,,,0,66,0.13,0.07,0.04,,0.11
2021-12-17,2021-12-24,Respiratory system,Acute respiratory distress syndrome,3,2,0,,,0,5,0.01,0.01,0.00,,0.01
2021-12-17,2021-12-24,Respiratory system,Subtotal n (%),3,2,0,,,0,5,0.01,0.01,0.00,,0.01
2021-12-17,2021-12-24,"Skin and mucous membrane, bone and joints system",Chilblains,13,5,1,,,0,19,0.03,0.03,0.04,,0.03
2021-12-17,2021-12-24,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),22,12,1,,,0,35,0.05,0.08,0.04,,0.06
2021-12-17,2021-12-24,"Skin and mucous membrane, bone and joints system",Subtotal n (%),35,17,2,,,0,54,0.08,0.12,0.07,,0.09
2021-12-17,2021-12-24,All AESI categories,TOTAL,3124,1205,614,,,33,4976,7.43,8.19,21.94,,8.35
2021-12-31,2022-01-07,Auto-immune diseases,Guillain-Barré Syndrome,50,23,39,,,0,112,0.10,0.14,1.39,,0.17
2021-12-31,2022-01-07,Auto-immune diseases,Thrombocytopenia (low blood platelets),19,11,39,,,3,72,0.04,0.07,1.39,,0.11
2021-12-31,2022-01-07,Auto-immune diseases,Subtotal n (%),69,34,78,,,3,184,0.14,0.21,2.78,,0.28
2021-12-31,2022-01-07,Cardiovascular system,Cardiac arrest,20,13,6,,,0,39,0.04,0.08,N/A,,0.06
2021-12-31,2022-01-07,Cardiovascular system,Cardiac failure,23,11,4,,,1,39,0.05,0.07,0.14,,0.06
2021-12-31,2022-01-07,Cardiovascular system,Myocardial infarction (heart attack),68,21,7,,,3,99,0.14,0.13,0.25,,0.15
2021-12-31,2022-01-07,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),991,549,29,,,5,1574,2.08,3.38,1.03,,2.36
2021-12-31,2022-01-07,Cardiovascular system,Subtotal n (%),1102,594,46,,,9,1751,2.31,3.66,1.64,,2.62
2021-12-31,2022-01-07,Circulatory system,Cerebral venous (sinus) thrombosis,4,1,12,,,0,17,0.01,0.01,0.43,,0.03
2021-12-31,2022-01-07,Circulatory system,Cerebral thrombosis ,6,4,1,,,0,11,0.01,0.02,0.04,,0.02
2021-12-31,2022-01-07,Circulatory system,Cutaneous vasculitis,16,8,8,,,0,32,0.03,0.05,0.29,,0.05
2021-12-31,2022-01-07,Circulatory system,Deep vein thrombosis,143,52,65,,,0,260,0.30,0.32,2.32,,0.39
2021-12-31,2022-01-07,Circulatory system,Embolism,5,4,6,,,0,15,0.01,0.02,0.21,,0.02
2021-12-31,2022-01-07,Circulatory system,Haemorrhage (bleeding),33,12,8,,,2,55,0.07,0.07,0.29,,0.08
2021-12-31,2022-01-07,Circulatory system,Pulmonary embolism,191,75,120,,,0,386,0.40,0.46,4.28,,0.58
2021-12-31,2022-01-07,Circulatory system,Thrombosis (blood clot),143,33,89,,,2,267,0.30,0.20,3.17,,0.40
2021-12-31,2022-01-07,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),19,6,64,,,0,89,0.04,0.04,2.28,,0.13
2021-12-31,2022-01-07,Circulatory system,Subtotal n (%),560,195,373,,,4,1132,1.17,1.20,13.30,,1.69
2021-12-31,2022-01-07,Hepato-gastrointestinal and renal system,Acute kidney injury,28,14,5,,,0,47,0.06,0.09,0.18,,0.07
2021-12-31,2022-01-07,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),7,3,1,,,0,11,0.01,0.02,0.04,,0.02
2021-12-31,2022-01-07,Hepato-gastrointestinal and renal system,Liver injury,19,8,3,,,0,30,0.04,0.05,0.11,,0.04
2021-12-31,2022-01-07,Hepato-gastrointestinal and renal system,Subtotal n (%),54,25,9,,,0,88,0.11,0.15,0.32,,0.13
2021-12-31,2022-01-07,Nerves and central nervous system,Bell's Palsy/facial paralysis*,505,158,50,,,1,714,1.06,0.97,1.78,,1.07
2021-12-31,2022-01-07,Nerves and central nervous system,Cerebrovascular accident (stroke),106,40,35,,,3,184,0.22,0.25,1.25,,0.28
2021-12-31,2022-01-07,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),26,9,6,,,0,41,0.05,0.06,0.21,,0.06
2021-12-31,2022-01-07,Nerves and central nervous system,Subtotal n (%),637,207,91,,,4,939,1.34,1.27,3.25,,1.41
2021-12-31,2022-01-07,Other system,Anaphylaxis*,542,159,27,,,1,729,1.14,0.98,0.96,,1.09
2021-12-31,2022-01-07,Other system,COVID-19*,159,8,1,,,13,181,0.33,0.05,0.04,,0.27
2021-12-31,2022-01-07,Other system,Multisystem inflammatory syndrome,6,1,0,,,0,7,0.01,0.01,0.00,,0.01
2021-12-31,2022-01-07,Other system,Subtotal n (%),707,168,28,,,14,917,1.48,1.03,1.00,,1.37
2021-12-31,2022-01-07,Pregnancy outcomes,Fetal growth restriction,5,0,0,,,0,5,0.01,0.00,0.00,,0.01
2021-12-31,2022-01-07,Pregnancy outcomes,Spontaneous abortion,50,14,1,,,0,65,0.10,0.09,0.04,,0.10
2021-12-31,2022-01-07,Pregnancy outcomes,Subtotal n (%),55,14,1,,,0,70,0.12,0.09,0.04,,0.10
2021-12-31,2022-01-07,Respiratory system,Acute respiratory distress syndrome,3,2,0,,,0,5,0.01,0.01,0.00,,0.01
2021-12-31,2022-01-07,Respiratory system,Subtotal n (%),3,2,0,,,0,5,0.01,0.01,0.00,,0.01
2021-12-31,2022-01-07,"Skin and mucous membrane, bone and joints system",Chilblains,13,5,1,,,0,19,0.03,0.03,0.04,,0.03
2021-12-31,2022-01-07,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),23,12,1,,,0,36,0.05,0.07,0.04,,0.05
2021-12-31,2022-01-07,"Skin and mucous membrane, bone and joints system",Subtotal n (%),36,17,2,,,0,55,0.08,0.10,0.07,,0.08
2021-12-31,2022-01-07,All AESI categories,TOTAL,3223,1256,628,,,34,5141,6.76,7.73,22.40,,7.70
2022-01-07,2022-01-14,Auto-immune diseases,Guillain-Barré Syndrome,51,23,39,0,,0,113,0.11,0.14,1.39,,0.17
2022-01-07,2022-01-14,Auto-immune diseases,Thrombocytopenia (low blood platelets),19,10,31,3,,0,63,0.04,0.06,1.11,,0.09
2022-01-07,2022-01-14,Auto-immune diseases,Subtotal n (%),70,33,70,3,,0,176,0.15,0.20,2.50,,0.26
2022-01-07,2022-01-14,Cardiovascular system,Cardiac arrest,21,13,6,0,,0,40,0.04,0.08,N/A,,0.06
2022-01-07,2022-01-14,Cardiovascular system,Cardiac failure,24,13,4,1,,0,42,0.05,0.08,N/A,,0.06
2022-01-07,2022-01-14,Cardiovascular system,Myocardial infarction (heart attack),71,21,7,3,,0,102,0.15,0.13,N/A,,0.15
2022-01-07,2022-01-14,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),1009,556,29,5,,0,1599,2.12,3.42,1.03,,2.39
2022-01-07,2022-01-14,Cardiovascular system,Subtotal n (%),1125,603,46,9,,0,1783,2.36,3.71,1.64,,2.67
2022-01-07,2022-01-14,Circulatory system,Cerebral venous (sinus) thrombosis,4,1,12,0,,0,17,N/A,N/A,0.43,,0.03
2022-01-07,2022-01-14,Circulatory system,Cerebral thrombosis ,6,3,1,0,,0,10,N/A,N/A,N/A,,0.01
2022-01-07,2022-01-14,Circulatory system,Cutaneous vasculitis,16,8,8,0,,0,32,0.03,N/A,N/A,,0.05
2022-01-07,2022-01-14,Circulatory system,Deep vein thrombosis,146,55,63,0,,0,264,0.31,0.34,2.25,,0.40
2022-01-07,2022-01-14,Circulatory system,Embolism,5,4,6,0,,0,15,N/A,N/A,N/A,,0.02
2022-01-07,2022-01-14,Circulatory system,Haemorrhage (bleeding),33,12,9,2,,0,56,0.07,0.07,N/A,,0.08
2022-01-07,2022-01-14,Circulatory system,Pulmonary embolism,194,76,119,0,,0,389,0.41,0.47,4.24,,0.58
2022-01-07,2022-01-14,Circulatory system,Thrombosis (blood clot),147,34,85,2,,0,268,0.31,0.21,3.03,,0.40
2022-01-07,2022-01-14,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),29,11,70,0,,0,110,0.06,0.07,2.50,,0.16
2022-01-07,2022-01-14,Circulatory system,Subtotal n (%),580,204,373,4,,0,1161,1.22,1.26,13.30,,1.74
2022-01-07,2022-01-14,Hepato-gastrointestinal and renal system,Acute kidney injury,29,16,5,0,,0,50,0.06,0.10,N/A,,0.07
2022-01-07,2022-01-14,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),8,3,1,0,,,12,N/A,N/A,N/A,,0.02
2022-01-07,2022-01-14,Hepato-gastrointestinal and renal system,Liver injury,19,8,3,0,,0,30,0.04,N/A,N/A,,0.04
2022-01-07,2022-01-14,Hepato-gastrointestinal and renal system,Subtotal n (%),56,27,9,0,,0,92,0.12,0.17,N/A,,0.14
2022-01-07,2022-01-14,Nerves and central nervous system,Bell's Palsy/facial paralysis*,509,160,51,1,,0,721,1.07,0.99,1.82,,1.08
2022-01-07,2022-01-14,Nerves and central nervous system,Cerebrovascular accident (stroke),110,42,35,3,,0,190,0.23,0.26,1.25,,0.28
2022-01-07,2022-01-14,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),26,9,6,0,,0,41,0.05,N/A,N/A,,0.06
2022-01-07,2022-01-14,Nerves and central nervous system,Subtotal n (%),645,211,92,4,,0,952,1.35,1.30,3.28,,1.43
2022-01-07,2022-01-14,Other system,Anaphylaxis*,552,159,27,1,,2,741,1.16,0.98,0.96,,1.11
2022-01-07,2022-01-14,Other system,COVID-19*,176,8,1,13,,0,198,0.37,N/A,N/A,,0.30
2022-01-07,2022-01-14,Other system,Multisystem inflammatory syndrome,6,1,0,0,,0,7,N/A,N/A,N/A,,N/A
2022-01-07,2022-01-14,Other system,Subtotal n (%),734,168,28,14,,2,946,1.54,1.03,1.00,,1.42
2022-01-07,2022-01-14,Pregnancy outcomes,Fetal growth restriction,5,0,0,0,,0,5,N/A,N/A,N/A,,N/A
2022-01-07,2022-01-14,Pregnancy outcomes,Spontaneous abortion,51,14,1,0,,0,66,0.11,0.09,N/A,,0.10
2022-01-07,2022-01-14,Pregnancy outcomes,Subtotal n (%),56,14,1,0,,0,71,0.12,0.09,N/A,,0.11
2022-01-07,2022-01-14,Respiratory system,Acute respiratory distress syndrome,3,2,0,0,,0,5,N/A,N/A,N/A,,N/A
2022-01-07,2022-01-14,Respiratory system,Subtotal n (%),3,2,0,0,,0,5,N/A,N/A,N/A,,N/A
2022-01-07,2022-01-14,"Skin and mucous membrane, bone and joints system",Chilblains,13,5,1,0,,0,19,0.03,N/A,N/A,,0.03
2022-01-07,2022-01-14,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),24,12,1,0,,0,37,0.05,0.07,N/A,,0.06
2022-01-07,2022-01-14,"Skin and mucous membrane, bone and joints system",Subtotal n (%),37,17,2,0,,0,56,0.08,0.10,N/A,,0.08
2022-01-07,2022-01-14,All AESI categories,TOTAL,3306,1279,621,34,,2,5242,6.93,7.87,22.15,,7.85
2022-01-14,2022-01-21,Auto-immune diseases,Guillain-Barré Syndrome,53,23,39,0,,0,115,0.11,0.12,1.40,,0.16
2022-01-14,2022-01-21,Auto-immune diseases,Thrombocytopenia (low blood platelets),19,10,31,0,,3,63,0.04,0.05,1.11,,0.09
2022-01-14,2022-01-21,Auto-immune diseases,Subtotal n (%),72,33,70,0,,3,178,0.14,0.18,2.51,,0.25
2022-01-14,2022-01-21,Cardiovascular system,Cardiac arrest,21,13,6,0,,0,40,0.04,0.07,N/A,,0.06
2022-01-14,2022-01-21,Cardiovascular system,Cardiac failure,24,14,4,0,,1,43,0.05,0.08,N/A,,0.06
2022-01-14,2022-01-21,Cardiovascular system,Myocardial infarction (heart attack),71,21,7,0,,3,102,0.14,0.11,N/A,,0.14
2022-01-14,2022-01-21,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),1045,563,29,0,,6,1643,2.10,3.05,1.04,,2.31
2022-01-14,2022-01-21,Cardiovascular system,Subtotal n (%),1161,611,46,0,,10,1828,2.34,3.31,1.65,,2.57
2022-01-14,2022-01-21,Circulatory system,Cerebral venous (sinus) thrombosis,4,1,12,0,,0,17,N/A,N/A,0.43,,0.02
2022-01-14,2022-01-21,Circulatory system,Cerebral thrombosis ,6,3,11,0,,0,20,N/A,N/A,0.39,,0.03
2022-01-14,2022-01-21,Circulatory system,Cutaneous vasculitis,16,8,8,0,,0,32,0.03,N/A,N/A,,0.05
2022-01-14,2022-01-21,Circulatory system,Deep vein thrombosis,150,55,63,0,,0,268,0.30,0.30,2.26,,0.38
2022-01-14,2022-01-21,Circulatory system,Embolism,6,4,6,0,,0,16,N/A,N/A,N/A,,0.02
2022-01-14,2022-01-21,Circulatory system,Haemorrhage (bleeding),35,12,9,0,,2,58,0.07,0.07,N/A,,0.08
2022-01-14,2022-01-21,Circulatory system,Pulmonary embolism,197,77,119,0,,1,394,0.40,0.42,4.26,,0.55
2022-01-14,2022-01-21,Circulatory system,Thrombosis (blood clot),147,35,86,0,,2,270,0.30,0.19,3.08,,0.38
2022-01-14,2022-01-21,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),24,11,71,0,,0,106,0.05,0.06,2.54,,0.15
2022-01-14,2022-01-21,Circulatory system,Subtotal n (%),585,206,385,0,,5,1181,1.18,1.12,13.80,,1.66
2022-01-14,2022-01-21,Hepato-gastrointestinal and renal system,Acute kidney injury,29,16,5,0,,0,50,0.06,0.09,N/A,,0.07
2022-01-14,2022-01-21,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),8,4,1,0,,0,13,N/A,N/A,N/A,,0.02
2022-01-14,2022-01-21,Hepato-gastrointestinal and renal system,Liver injury,19,8,3,0,,0,30,0.04,N/A,N/A,,0.04
2022-01-14,2022-01-21,Hepato-gastrointestinal and renal system,Subtotal n (%),56,28,9,0,,0,93,0.11,0.15,N/A,,0.13
2022-01-14,2022-01-21,Nerves and central nervous system,Bell's Palsy/facial paralysis*,526,168,54,0,,0,748,1.06,0.91,1.94,,1.05
2022-01-14,2022-01-21,Nerves and central nervous system,Cerebrovascular accident (stroke),111,42,35,0,,3,191,0.22,0.23,1.25,,0.27
2022-01-14,2022-01-21,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),26,10,6,0,,0,42,0.05,0.05,N/A,,0.06
2022-01-14,2022-01-21,Nerves and central nervous system,Subtotal n (%),663,220,95,0,,3,981,1.33,1.19,3.40,,1.38
2022-01-14,2022-01-21,Other system,Anaphylaxis*,551,159,27,2,,1,740,1.11,0.86,0.97,,1.04
2022-01-14,2022-01-21,Other system,COVID-19*,176,8,1,0,,13,198,0.35,N/A,N/A,,0.28
2022-01-14,2022-01-21,Other system,Multisystem inflammatory syndrome,6,1,0,0,,0,7,N/A,N/A,N/A,,N/A
2022-01-14,2022-01-21,Other system,Subtotal n (%),733,168,28,2,,14,945,1.47,0.91,1.00,,1.33
2022-01-14,2022-01-21,Pregnancy outcomes,Fetal growth restriction,5,0,0,0,,0,5,N/A,0.00,0.00,,0.01
2022-01-14,2022-01-21,Pregnancy outcomes,Spontaneous abortion,51,14,1,0,,0,66,0.10,0.08,N/A,,0.09
2022-01-14,2022-01-21,Pregnancy outcomes,Subtotal n (%),56,14,1,0,,0,71,0.11,0.08,N/A,,0.10
2022-01-14,2022-01-21,Respiratory system,Acute respiratory distress syndrome,3,2,0,0,,0,5,N/A,N/A,N/A,,N/A
2022-01-14,2022-01-21,Respiratory system,Subtotal n (%),3,2,0,0,,0,5,N/A,N/A,N/A,,N/A
2022-01-14,2022-01-21,"Skin and mucous membrane, bone and joints system",Chilblains,13,5,1,0,,0,19,0.03,N/A,N/A,,0.03
2022-01-14,2022-01-21,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),24,12,1,0,,0,37,0.05,0.07,N/A,,0.05
2022-01-14,2022-01-21,"Skin and mucous membrane, bone and joints system",Subtotal n (%),37,17,2,0,,0,56,0.07,0.09,N/A,,0.08
2022-01-14,2022-01-21,All AESI categories,TOTAL,3366,1299,636,2,,35,5338,6.77,7.04,22.79,,7.51
2022-01-21,2022-01-28,Auto-immune diseases,Guillain-Barré Syndrome,54,23,39,0,,0,116,0.11,0.11,1.40,,0.16
2022-01-21,2022-01-28,Auto-immune diseases,Thrombocytopenia (low blood platelets),19,10,31,3,,0,63,0.04,0.05,1.11,,0.09
2022-01-21,2022-01-28,Auto-immune diseases,Subtotal n (%),73,33,70,3,,0,179,0.14,0.16,2.51,,0.24
2022-01-21,2022-01-28,Cardiovascular system,Cardiac arrest,21,13,6,0,,0,40,0.04,0.06,N/A,,0.05
2022-01-21,2022-01-28,Cardiovascular system,Cardiac failure,25,15,4,1,,0,45,0.05,0.07,N/A,,0.06
2022-01-21,2022-01-28,Cardiovascular system,Myocardial infarction (heart attack),73,21,7,3,,0,104,0.14,0.10,N/A,,0.14
2022-01-21,2022-01-28,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),1073,572,30,5,,0,1680,2.12,2.85,1.07,,2.28
2022-01-21,2022-01-28,Cardiovascular system,Subtotal n (%),1192,621,47,9,,0,1869,2.35,3.10,1.68,,2.54
2022-01-21,2022-01-28,Circulatory system,Cerebral venous (sinus) thrombosis,4,2,12,0,,0,18,N/A,N/A,0.43,,0.02
2022-01-21,2022-01-28,Circulatory system,Cerebral thrombosis ,6,3,1,0,,0,10,N/A,N/A,N/A,,0.01
2022-01-21,2022-01-28,Circulatory system,Cutaneous vasculitis,17,8,8,0,,0,33,0.03,N/A,N/A,,0.04
2022-01-21,2022-01-28,Circulatory system,Deep vein thrombosis,154,57,63,0,,0,274,0.30,0.28,2.26,,0.37
2022-01-21,2022-01-28,Circulatory system,Embolism,6,4,6,0,,0,16,N/A,N/A,N/A,,0.02
2022-01-21,2022-01-28,Circulatory system,Haemorrhage (bleeding),37,13,9,3,,0,62,0.07,0.06,N/A,,0.08
2022-01-21,2022-01-28,Circulatory system,Pulmonary embolism,203,79,119,1,,0,402,0.40,0.39,4.26,,0.55
2022-01-21,2022-01-28,Circulatory system,Thrombosis (blood clot),150,35,86,2,,0,273,0.30,0.17,3.08,,0.37
2022-01-21,2022-01-28,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),25,11,71,0,,0,107,0.05,0.05,2.54,,0.15
2022-01-21,2022-01-28,Circulatory system,Subtotal n (%),602,212,375,6,,0,1195,1.19,1.06,13.43,,1.62
2022-01-21,2022-01-28,Hepato-gastrointestinal and renal system,Acute kidney injury,29,16,6,0,,0,51,0.06,0.08,N/A,,0.07
2022-01-21,2022-01-28,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),9,4,1,0,,0,14,N/A,N/A,N/A,,0.02
2022-01-21,2022-01-28,Hepato-gastrointestinal and renal system,Liver injury,19,8,3,0,,0,30,0.04,N/A,N/A,,0.04
2022-01-21,2022-01-28,Hepato-gastrointestinal and renal system,Subtotal n (%),57,28,10,0,,0,95,0.11,0.14,0.36,,0.13
2022-01-21,2022-01-28,Nerves and central nervous system,Bell's Palsy/facial paralysis*,533,172,54,1,,0,760,1.05,0.86,1.93,,1.03
2022-01-21,2022-01-28,Nerves and central nervous system,Cerebrovascular accident (stroke),113,43,35,3,,0,194,0.22,0.21,1.25,,0.26
2022-01-21,2022-01-28,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),27,11,6,0,,0,44,0.05,0.05,N/A,,0.06
2022-01-21,2022-01-28,Nerves and central nervous system,Subtotal n (%),673,226,95,4,,0,998,1.33,1.13,3.40,,1.36
2022-01-21,2022-01-28,Other system,Anaphylaxis*,553,161,27,1,,2,744,1.09,0.80,0.97,,1.01
2022-01-21,2022-01-28,Other system,COVID-19*,219,13,1,19,,0,252,0.43,0.06,N/A,,0.34
2022-01-21,2022-01-28,Other system,Multisystem inflammatory syndrome,8,1,0,0,,0,9,N/A,N/A,N/A,,N/A
2022-01-21,2022-01-28,Other system,Subtotal n (%),780,175,28,20,,2,1005,1.54,0.87,1.00,,1.37
2022-01-21,2022-01-28,Pregnancy outcomes,Fetal growth restriction,5,0,0,0,,0,5,N/A,N/A,N/A,,N/A
2022-01-21,2022-01-28,Pregnancy outcomes,Spontaneous abortion,52,11,1,0,,0,64,0.10,0.05,N/A,,0.09
2022-01-21,2022-01-28,Pregnancy outcomes,Subtotal n (%),57,11,1,0,,0,69,0.11,0.05,N/A,,0.09
2022-01-21,2022-01-28,Respiratory system,Acute respiratory distress syndrome,3,2,0,0,,0,5,N/A,N/A,N/A,,N/A
2022-01-21,2022-01-28,Respiratory system,Subtotal n (%),3,2,0,0,,0,5,N/A,N/A,N/A,,N/A
2022-01-21,2022-01-28,"Skin and mucous membrane, bone and joints system",Chilblains,14,5,1,0,,0,20,0.03,N/A,N/A,,0.03
2022-01-21,2022-01-28,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),24,12,2,0,,0,38,0.05,0.06,N/A,,0.05
2022-01-21,2022-01-28,"Skin and mucous membrane, bone and joints system",Subtotal n (%),38,17,3,0,,0,58,0.08,0.08,N/A,,0.08
2022-01-21,2022-01-28,All AESI categories,TOTAL,3475,1325,629,42,,2,5473,6.86,6.61,22.53,,7.44
2022-01-28,2022-02-04,Auto-immune diseases,Guillain-Barré Syndrome,54,24,39,0,,0,117,0.10,0.11,1.40,,0.15
2022-01-28,2022-02-04,Auto-immune diseases,Thrombocytopenia (low blood platelets),110,38,78,2,,1,229,0.21,0.18,2.79,,0.30
2022-01-28,2022-02-04,Auto-immune diseases,Subtotal n (%),164,62,117,2,,1,346,0.32,0.29,4.19,,0.46
2022-01-28,2022-02-04,Cardiovascular system,Cardiac arrest,21,12,6,0,,0,39,0.04,0.06,N/A,,0.05
2022-01-28,2022-02-04,Cardiovascular system,Cardiac failure,25,15,4,0,,0,44,0.05,0.07,N/A,,0.06
2022-01-28,2022-02-04,Cardiovascular system,Myocardial infarction (heart attack),70,21,7,0,,1,99,0.14,0.10,N/A,,0.13
2022-01-28,2022-02-04,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),1096,589,30,0,,5,1720,2.12,2.77,1.07,,2.27
2022-01-28,2022-02-04,Cardiovascular system,Subtotal n (%),1212,637,47,0,,6,1902,2.35,3.00,1.07,,2.51
2022-01-28,2022-02-04,Circulatory system,Cerebral venous (sinus) thrombosis,4,2,11,0,,0,17,N/A,N/A,0.39,,0.02
2022-01-28,2022-02-04,Circulatory system,Cerebral thrombosis ,6,3,0,0,,0,9,N/A,N/A,N/A,,N/A
2022-01-28,2022-02-04,Circulatory system,Cutaneous vasculitis,17,8,8,0,,0,33,0.03,N/A,N/A,,0.04
2022-01-28,2022-02-04,Circulatory system,Deep vein thrombosis,156,60,63,0,,0,279,0.30,0.28,2.26,,0.37
2022-01-28,2022-02-04,Circulatory system,Embolism,5,4,7,0,,0,16,N/A,N/A,N/A,,0.02
2022-01-28,2022-02-04,Circulatory system,Haemorrhage (bleeding),37,13,9,0,,3,62,0.07,0.06,N/A,,0.08
2022-01-28,2022-02-04,Circulatory system,Pulmonary embolism,206,83,120,0,,1,410,0.40,0.39,4.30,,0.54
2022-01-28,2022-02-04,Circulatory system,Thrombosis (blood clot),153,35,86,0,,2,276,0.30,0.16,3.08,,0.36
2022-01-28,2022-02-04,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),25,11,71,0,,0,107,0.05,0.05,2.54,,0.14
2022-01-28,2022-02-04,Circulatory system,Subtotal n (%),609,219,375,0,,6,1209,1.18,1.03,13.43,,1.58
2022-01-28,2022-02-04,Hepato-gastrointestinal and renal system,Acute kidney injury,30,16,6,0,,0,52,0.06,0.08,N/A,,0.07
2022-01-28,2022-02-04,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),11,4,1,0,,0,16,0.02,N/A,N/A,,0.02
2022-01-28,2022-02-04,Hepato-gastrointestinal and renal system,Liver injury,19,9,3,0,,0,31,0.04,N/A,N/A,,0.04
2022-01-28,2022-02-04,Hepato-gastrointestinal and renal system,Subtotal n (%),60,29,10,0,,0,99,0.12,0.08,0.01,,0.13
2022-01-28,2022-02-04,Nerves and central nervous system,Bell's Palsy/facial paralysis*,541,180,53,11,,1,775,1.05,0.85,1.90,,1.02
2022-01-28,2022-02-04,Nerves and central nervous system,Cerebrovascular accident (stroke),114,45,35,0,,3,197,0.22,0.21,1.25,,0.26
2022-01-28,2022-02-04,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),29,11,6,0,,0,46,0.06,0.05,N/A,,0.06
2022-01-28,2022-02-04,Nerves and central nervous system,Subtotal n (%),684,236,94,11,,4,1018,1.33,1.11,3.15,,1.34
2022-01-28,2022-02-04,Other system,Anaphylaxis*,560,162,27,2,,1,752,1.09,0.76,0.97,,0.99
2022-01-28,2022-02-04,Other system,COVID-19*,241,10,2,0,,14,267,0.47,0.05,N/A,,0.35
2022-01-28,2022-02-04,Other system,Multisystem inflammatory syndrome,9,1,0,0,,0,10,N/A,N/A,N/A,,0.01
2022-01-28,2022-02-04,Other system,Subtotal n (%),810,173,29,2,,15,1029,1.55,0.81,0.97,,1.36
2022-01-28,2022-02-04,Pregnancy outcomes,Fetal growth restriction,5,0,0,0,,0,5,N/A,N/A,N/A,,N/A
2022-01-28,2022-02-04,Pregnancy outcomes,Spontaneous abortion,53,12,1,0,,0,66,0.10,0.06,N/A,,0.09
2022-01-28,2022-02-04,Pregnancy outcomes,Subtotal n (%),58,12,1,0,,0,71,0.10,0.06,N/A,,0.09
2022-01-28,2022-02-04,Respiratory system,Acute respiratory distress syndrome,3,2,0,0,,0,5,N/A,N/A,N/A,,N/A
2022-01-28,2022-02-04,Respiratory system,Subtotal n (%),3,2,0,0,,0,5,N/A,N/A,N/A,,N/A
2022-01-28,2022-02-04,"Skin and mucous membrane, bone and joints system",Chilblains,14,5,1,0,,0,20,0.03,N/A,N/A,,0.03
2022-01-28,2022-02-04,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),24,12,2,0,,0,38,0.05,0.06,N/A,,0.05
2022-01-28,2022-02-04,"Skin and mucous membrane, bone and joints system",Subtotal n (%),38,17,3,0,,0,58,0.07,0.06,N/A,,0.08
2022-01-28,2022-02-04,All AESI categories,TOTAL,3638,1387,676,15,,32,5737,7.02,6.43,22.81,,7.56
2022-02-04,2022-02-11,Auto-immune diseases,Guillain-Barré Syndrome,54,25,39,0,,0,118,0.10,0.11,1.40,,0.15
2022-02-04,2022-02-11,Auto-immune diseases,Thrombocytopenia (low blood platelets),145,62,120,1,,1,329,0.28,0.28,4.30,,0.42
2022-02-04,2022-02-11,Auto-immune diseases,Subtotal n (%),199,87,159,1,,1,447,0.38,0.40,5.69,,0.58
2022-02-04,2022-02-11,Cardiovascular system,Cardiac arrest,21,14,6,0,,0,41,0.04,0.06,N/A,,0.05
2022-02-04,2022-02-11,Cardiovascular system,Cardiac failure,25,15,4,0,,1,45,0.05,0.07,N/A,,0.06
2022-02-04,2022-02-11,Cardiovascular system,Myocardial infarction (heart attack),74,21,7,0,,3,105,0.14,0.10,N/A,,0.14
2022-02-04,2022-02-11,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),1104,594,30,1,,5,1734,2.10,2.70,1.07,,2.24
2022-02-04,2022-02-11,Cardiovascular system,Subtotal n (%),1224,644,47,1,,9,1925,2.33,2.93,1.68,,2.49
2022-02-04,2022-02-11,Circulatory system,Cerebral venous (sinus) thrombosis,4,3,12,0,,0,19,N/A,N/A,0.43,,0.02
2022-02-04,2022-02-11,Circulatory system,Cerebral thrombosis ,6,3,1,0,,0,10,N/A,N/A,N/A,,0.01
2022-02-04,2022-02-11,Circulatory system,Cutaneous vasculitis,19,8,8,0,,0,35,0.04,N/A,N/A,,0.05
2022-02-04,2022-02-11,Circulatory system,Deep vein thrombosis,158,63,64,0,,0,285,0.30,0.29,2.29,,0.37
2022-02-04,2022-02-11,Circulatory system,Embolism,5,4,7,0,,0,16,N/A,N/A,N/A,,0.02
2022-02-04,2022-02-11,Circulatory system,Haemorrhage (bleeding),38,14,9,0,,3,64,0.07,0.06,N/A,,0.08
2022-02-04,2022-02-11,Circulatory system,Pulmonary embolism,209,85,120,0,,1,415,0.40,0.39,4.29,,0.54
2022-02-04,2022-02-11,Circulatory system,Thrombosis (blood clot),153,34,85,0,,2,274,0.29,0.15,3.04,,0.35
2022-02-04,2022-02-11,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),25,11,71,0,,0,107,0.05,0.05,2.54,,0.14
2022-02-04,2022-02-11,Circulatory system,Subtotal n (%),617,225,377,0,,6,1225,1.17,1.02,13.49,,1.58
2022-02-04,2022-02-11,Hepato-gastrointestinal and renal system,Acute kidney injury,31,17,6,0,,0,54,0.06,0.08,N/A,,0.07
2022-02-04,2022-02-11,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),11,4,1,0,,0,16,0.02,N/A,N/A,,0.02
2022-02-04,2022-02-11,Hepato-gastrointestinal and renal system,Liver injury,23,10,3,0,,0,36,0.04,0.05,N/A,,0.05
2022-02-04,2022-02-11,Hepato-gastrointestinal and renal system,Subtotal n (%),65,31,10,0,,0,106,0.12,0.14,0.36,,0.14
2022-02-04,2022-02-11,Nerves and central nervous system,Bell's Palsy/facial paralysis*,555,188,54,0,,1,798,1.06,0.85,1.93,,1.03
2022-02-04,2022-02-11,Nerves and central nervous system,Cerebrovascular accident (stroke),116,45,35,0,,3,199,0.22,0.20,1.25,,0.26
2022-02-04,2022-02-11,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),27,11,6,0,,0,44,0.05,0.05,N/A,,0.06
2022-02-04,2022-02-11,Nerves and central nervous system,Subtotal n (%),698,244,95,0,,4,1041,1.33,1.11,3.40,,1.34
2022-02-04,2022-02-11,Other system,Anaphylaxis*,567,166,27,2,,1,763,1.08,0.75,0.97,,0.99
2022-02-04,2022-02-11,Other system,COVID-19*,265,11,1,0,,15,292,0.50,0.05,N/A,,0.38
2022-02-04,2022-02-11,Other system,Multisystem inflammatory syndrome,11,1,0,0,,0,12,0.02,N/A,N/A,,0.02
2022-02-04,2022-02-11,Other system,Subtotal n (%),843,178,28,2,,16,1067,1.60,0.81,1.00,,1.38
2022-02-04,2022-02-11,Pregnancy outcomes,Fetal growth restriction,5,0,0,0,,0,5,N/A,N/A,N/A,,N/A
2022-02-04,2022-02-11,Pregnancy outcomes,Spontaneous abortion,55,12,1,0,,0,68,0.10,0.05,N/A,,0.09
2022-02-04,2022-02-11,Pregnancy outcomes,Subtotal n (%),60,12,1,0,,0,73,0.11,0.05,N/A,,0.09
2022-02-04,2022-02-11,Respiratory system,Acute respiratory distress syndrome,3,2,0,0,,0,5,N/A,N/A,N/A,,N/A
2022-02-04,2022-02-11,Respiratory system,Subtotal n (%),3,2,0,0,,0,5,N/A,N/A,N/A,,N/A
2022-02-04,2022-02-11,"Skin and mucous membrane, bone and joints system",Chilblains,14,5,1,0,,0,20,0.03,N/A,N/A,,0.03
2022-02-04,2022-02-11,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),26,12,2,0,,0,40,0.05,0.05,N/A,,0.05
2022-02-04,2022-02-11,"Skin and mucous membrane, bone and joints system",Subtotal n (%),40,17,3,0,,0,60,0.08,0.08,N/A,,0.08
2022-02-04,2022-02-11,All AESI categories,TOTAL,3749,1440,720,4,,36,5949,7.14,6.55,25.77,,7.68
2022-02-11,2022-02-18,Auto-immune diseases,Guillain-Barré Syndrome,54,26,39,0,,1,120,0.10,0.12,1.40,,0.15
2022-02-11,2022-02-18,Auto-immune diseases,Thrombocytopenia (low blood platelets),147,64,123,1,,1,336,0.28,0.29,4.40,,0.43
2022-02-11,2022-02-18,Auto-immune diseases,Subtotal n (%),201,90,162,1,,2,456,0.38,0.40,5.80,,0.58
2022-02-11,2022-02-18,Cardiovascular system,Cardiac arrest,21,14,6,0,,0,41,0.04,0.06,N/A,,0.05
2022-02-11,2022-02-18,Cardiovascular system,Cardiac failure,25,15,4,0,,1,45,0.05,0.07,N/A,,0.06
2022-02-11,2022-02-18,Cardiovascular system,Myocardial infarction (heart attack),72,22,7,0,,3,104,0.14,0.10,N/A,,0.13
2022-02-11,2022-02-18,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),1134,604,31,1,,5,1775,2.13,2.70,1.11,,2.26
2022-02-11,2022-02-18,Cardiovascular system,Subtotal n (%),1252,655,48,1,,9,1965,2.35,2.93,1.72,,2.50
2022-02-11,2022-02-18,Circulatory system,Cerebral venous (sinus) thrombosis,4,3,12,0,,0,19,N/A,N/A,0.43,,0.02
2022-02-11,2022-02-18,Circulatory system,Cerebral thrombosis ,6,3,1,0,,0,10,N/A,N/A,N/A,,0.01
2022-02-11,2022-02-18,Circulatory system,Cutaneous vasculitis,19,8,8,0,,0,35,0.04,N/A,N/A,,0.04
2022-02-11,2022-02-18,Circulatory system,Deep vein thrombosis,161,63,65,0,,0,289,0.30,0.28,2.33,,0.37
2022-02-11,2022-02-18,Circulatory system,Embolism,5,4,7,0,,0,16,N/A,N/A,N/A,,0.02
2022-02-11,2022-02-18,Circulatory system,Haemorrhage (bleeding),39,14,9,0,,3,65,0.07,0.06,N/A,,0.08
2022-02-11,2022-02-18,Circulatory system,Pulmonary embolism,209,86,123,0,,1,419,0.39,0.38,4.40,,0.53
2022-02-11,2022-02-18,Circulatory system,Thrombosis (blood clot),162,39,87,0,,2,290,0.30,0.17,3.11,,0.37
2022-02-11,2022-02-18,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),27,12,71,0,,0,110,0.05,0.05,2.54,,0.14
2022-02-11,2022-02-18,Circulatory system,Subtotal n (%),632,232,383,0,,6,1253,1.19,1.04,13.70,,1.58
2022-02-11,2022-02-18,Hepato-gastrointestinal and renal system,Acute kidney injury,32,17,6,0,,0,55,0.06,0.08,N/A,,0.07
2022-02-11,2022-02-18,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),11,4,1,0,,0,16,0.02,N/A,N/A,,0.02
2022-02-11,2022-02-18,Hepato-gastrointestinal and renal system,Liver injury,23,10,3,0,,0,36,0.04,0.04,N/A,,0.05
2022-02-11,2022-02-18,Hepato-gastrointestinal and renal system,Subtotal n (%),66,31,10,0,,0,107,0.12,0.14,0.36,,0.14
2022-02-11,2022-02-18,Nerves and central nervous system,Bell's Palsy/facial paralysis*,565,190,54,0,,1,810,1.06,0.85,1.93,,1.03
2022-02-11,2022-02-18,Nerves and central nervous system,Cerebrovascular accident (stroke),118,45,35,0,,3,201,0.22,0.20,1.25,,0.26
2022-02-11,2022-02-18,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),13,6,1,0,,0,20,0.02,N/A,N/A,,0.03
2022-02-11,2022-02-18,Nerves and central nervous system,Subtotal n (%),696,241,90,0,,4,1031,1.31,1.08,3.22,,1.31
2022-02-11,2022-02-18,Other system,Anaphylaxis*,572,171,27,3,,1,774,1.07,0.76,0.97,,0.99
2022-02-11,2022-02-18,Other system,COVID-19*,294,11,2,0,,16,323,0.55,0.05,N/A,,0.41
2022-02-11,2022-02-18,Other system,Multisystem inflammatory syndrome,11,1,0,0,,0,12,0.02,N/A,N/A,,0.02
2022-02-11,2022-02-18,Other system,Subtotal n (%),877,183,29,3,,17,1109,1.65,0.82,1.04,,1.41
2022-02-11,2022-02-18,Pregnancy outcomes,Fetal growth restriction,5,0,0,0,,0,5,N/A,N/A,N/A,,N/A
2022-02-11,2022-02-18,Pregnancy outcomes,Spontaneous abortion,57,12,1,0,,0,70,0.11,0.05,N/A,,0.09
2022-02-11,2022-02-18,Pregnancy outcomes,Subtotal n (%),62,12,1,0,,0,75,0.12,0.05,N/A,,0.10
2022-02-11,2022-02-18,Respiratory system,Acute respiratory distress syndrome,3,2,0,0,,0,5,N/A,N/A,N/A,,N/A
2022-02-11,2022-02-18,Respiratory system,Subtotal n (%),3,2,0,0,,0,5,N/A,N/A,N/A,,N/A
2022-02-11,2022-02-18,"Skin and mucous membrane, bone and joints system",Chilblains,18,5,2,0,,0,25,0.03,N/A,N/A,,0.03
2022-02-11,2022-02-18,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),26,13,2,0,,0,41,0.05,0.06,N/A,,0.05
2022-02-11,2022-02-18,"Skin and mucous membrane, bone and joints system",Subtotal n (%),44,18,4,0,,0,66,0.08,0.08,N/A,,0.08
2022-02-11,2022-02-18,All AESI categories,TOTAL,3833,1464,727,5,,38,6067,7.20,6.55,26.01,,7.72
2022-02-18,2022-02-25,Auto-immune diseases,Guillain-Barré Syndrome,54,27,39,0,,1,121,0.10,0.12,1.40,,0.15
2022-02-18,2022-02-25,Auto-immune diseases,Thrombocytopenia (low blood platelets),120,47,81,1,,1,250,0.22,0.21,2.90,,0.32
2022-02-18,2022-02-25,Auto-immune diseases,Subtotal n (%),174,74,120,1,,2,371,0.32,0.33,4.29,,0.47
2022-02-18,2022-02-25,Cardiovascular system,Cardiac arrest,21,14,6,0,,0,41,0.04,0.06,N/A,,0.05
2022-02-18,2022-02-25,Cardiovascular system,Cardiac failure,25,15,4,0,,1,45,0.05,0.07,N/A,,0.06
2022-02-18,2022-02-25,Cardiovascular system,Myocardial infarction (heart attack),73,21,6,0,,3,103,0.14,0.09,N/A,,0.13
2022-02-18,2022-02-25,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),1151,618,31,1,,5,1806,2.14,2.74,1.11,,2.28
2022-02-18,2022-02-25,Cardiovascular system,Subtotal n (%),1270,668,47,1,,9,1995,2.36,2.96,1.68,,2.51
2022-02-18,2022-02-25,Circulatory system,Cerebral venous (sinus) thrombosis,5,3,12,0,,0,20,N/A,N/A,0.43,,0.03
2022-02-18,2022-02-25,Circulatory system,Cerebral thrombosis ,6,3,1,0,,0,10,N/A,N/A,N/A,,0.01
2022-02-18,2022-02-25,Circulatory system,Cutaneous vasculitis,19,8,8,0,,0,35,0.04,N/A,N/A,,0.04
2022-02-18,2022-02-25,Circulatory system,Deep vein thrombosis,161,63,65,0,,0,289,0.30,0.28,2.33,,0.36
2022-02-18,2022-02-25,Circulatory system,Embolism,5,4,7,0,,0,16,N/A,N/A,N/A,,0.02
2022-02-18,2022-02-25,Circulatory system,Haemorrhage (bleeding),39,14,10,0,,3,66,0.07,0.06,0.36,,0.08
2022-02-18,2022-02-25,Circulatory system,Pulmonary embolism,213,87,124,0,,0,424,0.40,0.39,4.44,,0.53
2022-02-18,2022-02-25,Circulatory system,Thrombosis (blood clot),82,120,87,0,,2,291,0.15,0.53,3.11,,0.37
2022-02-18,2022-02-25,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),27,12,71,0,,0,110,0.05,0.05,2.54,,0.14
2022-02-18,2022-02-25,Circulatory system,Subtotal n (%),557,314,385,0,,5,1261,1.03,1.39,13.77,,1.59
2022-02-18,2022-02-25,Hepato-gastrointestinal and renal system,Acute kidney injury,32,18,6,0,,0,56,0.06,0.08,N/A,,0.07
2022-02-18,2022-02-25,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),12,4,1,0,,0,17,0.02,N/A,N/A,,0.02
2022-02-18,2022-02-25,Hepato-gastrointestinal and renal system,Liver injury,24,11,3,0,,0,38,0.04,0.05,N/A,,0.05
2022-02-18,2022-02-25,Hepato-gastrointestinal and renal system,Subtotal n (%),68,33,10,0,,0,111,0.13,0.15,0.36,,0.14
2022-02-18,2022-02-25,Nerves and central nervous system,Bell's Palsy/facial paralysis*,572,197,55,0,,1,825,1.06,0.87,1.97,,1.04
2022-02-18,2022-02-25,Nerves and central nervous system,Cerebrovascular accident (stroke),121,46,35,0,,3,205,0.22,0.20,1.25,,0.26
2022-02-18,2022-02-25,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),8,5,0,0,,0,13,N/A,N/A,N/A,,0.02
2022-02-18,2022-02-25,Nerves and central nervous system,Subtotal n (%),701,248,90,0,,4,1043,1.30,1.10,3.22,,1.31
2022-02-18,2022-02-25,Other system,Anaphylaxis*,579,173,28,3,,1,784,1.08,0.77,1.00,,0.99
2022-02-18,2022-02-25,Other system,COVID-19*,310,14,2,0,,17,343,0.58,0.06,N/A,,0.43
2022-02-18,2022-02-25,Other system,Multisystem inflammatory syndrome,12,1,0,0,,0,13,0.02,N/A,N/A,,0.02
2022-02-18,2022-02-25,Other system,Subtotal n (%),901,188,30,3,,18,1140,1.67,0.84,1.07,,1.44
2022-02-18,2022-02-25,Pregnancy outcomes,Fetal growth restriction,5,0,0,0,,0,5,N/A,N/A,N/A,,N/A
2022-02-18,2022-02-25,Pregnancy outcomes,Spontaneous abortion,57,12,1,0,,0,70,0.11,0.05,N/A,,0.09
2022-02-18,2022-02-25,Pregnancy outcomes,Subtotal n (%),62,12,1,0,,0,75,0.12,0.05,N/A,,0.09
2022-02-18,2022-02-25,Respiratory system,Acute respiratory distress syndrome,3,2,0,0,,0,5,N/A,N/A,N/A,,N/A
2022-02-18,2022-02-25,Respiratory system,Subtotal n (%),3,2,0,0,,0,5,N/A,N/A,N/A,,N/A
2022-02-18,2022-02-25,"Skin and mucous membrane, bone and joints system",Chilblains,18,5,2,0,,0,25,0.03,N/A,N/A,,0.03
2022-02-18,2022-02-25,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),26,13,2,0,,0,41,0.05,0.06,N/A,,0.05
2022-02-18,2022-02-25,"Skin and mucous membrane, bone and joints system",Subtotal n (%),44,18,4,0,,0,66,0.08,0.08,N/A,,0.08
2022-02-18,2022-02-25,All AESI categories,TOTAL,3780,1557,687,5,,38,6067,7.02,6.89,24.57,,7.65
2022-02-25,2022-03-04,Auto-immune diseases,Guillain-Barré Syndrome,55,27,39,0,,1,122,0.10,0.12,1.39,,0.15
2022-02-25,2022-03-04,Auto-immune diseases,Thrombocytopenia (low blood platelets),120,47,81,1,,1,250,0.22,0.21,2.90,,0.31
2022-02-25,2022-03-04,Auto-immune diseases,Subtotal n (%),175,74,120,1,,2,372,0.32,0.33,4.29,,0.47
2022-02-25,2022-03-04,Cardiovascular system,Cardiac arrest,21,14,6,0,,0,41,0.04,0.06,N/A,,0.05
2022-02-25,2022-03-04,Cardiovascular system,Cardiac failure,25,16,4,0,,1,46,0.05,0.07,N/A,,0.06
2022-02-25,2022-03-04,Cardiovascular system,Myocardial infarction (heart attack),73,21,6,1,,3,104,0.13,0.09,N/A,,0.13
2022-02-25,2022-03-04,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),1178,641,32,1,,5,1857,2.17,2.82,1.14,,2.32
2022-02-25,2022-03-04,Cardiovascular system,Subtotal n (%),1297,692,48,2,,9,2048,2.39,3.04,1.72,,2.56
2022-02-25,2022-03-04,Circulatory system,Cerebral venous (sinus) thrombosis,5,3,12,0,,0,20,N/A,N/A,0.43,,0.03
2022-02-25,2022-03-04,Circulatory system,Cerebral thrombosis ,6,3,1,0,,0,10,N/A,N/A,N/A,,0.01
2022-02-25,2022-03-04,Circulatory system,Cutaneous vasculitis,19,8,8,0,,0,35,0.04,N/A,N/A,,0.04
2022-02-25,2022-03-04,Circulatory system,Deep vein thrombosis,167,65,65,0,,0,297,0.31,0.29,2.32,,0.37
2022-02-25,2022-03-04,Circulatory system,Embolism,5,4,7,0,,0,16,N/A,N/A,N/A,,0.02
2022-02-25,2022-03-04,Circulatory system,Haemorrhage (bleeding),40,14,10,0,,3,67,0.07,0.06,0.36,,0.08
2022-02-25,2022-03-04,Circulatory system,Pulmonary embolism,217,89,125,1,,0,432,0.40,0.39,4.47,,0.54
2022-02-25,2022-03-04,Circulatory system,Thrombosis (blood clot),166,41,87,0,,2,296,0.31,0.18,3.11,,0.37
2022-02-25,2022-03-04,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),27,12,69,0,,0,108,0.05,0.05,2.47,,0.14
2022-02-25,2022-03-04,Circulatory system,Subtotal n (%),652,239,384,1,,5,1281,1.20,1.05,13.73,,1.60
2022-02-25,2022-03-04,Hepato-gastrointestinal and renal system,Acute kidney injury,32,19,6,0,,0,57,0.06,0.08,N/A,,0.07
2022-02-25,2022-03-04,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),12,4,1,0,,0,17,0.02,N/A,N/A,,0.02
2022-02-25,2022-03-04,Hepato-gastrointestinal and renal system,Liver injury,24,11,3,0,,0,38,0.04,0.05,N/A,,0.05
2022-02-25,2022-03-04,Hepato-gastrointestinal and renal system,Subtotal n (%),68,34,10,0,,0,112,0.13,0.15,0.36,,0.14
2022-02-25,2022-03-04,Nerves and central nervous system,Bell's Palsy/facial paralysis*,578,201,55,0,,0,834,1.06,0.88,1.97,,1.04
2022-02-25,2022-03-04,Nerves and central nervous system,Cerebrovascular accident (stroke),123,49,36,0,,4,212,0.23,0.22,1.29,,0.27
2022-02-25,2022-03-04,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),8,5,0,0,,0,13,N/A,N/A,N/A,,0.02
2022-02-25,2022-03-04,Nerves and central nervous system,Subtotal n (%),709,255,91,0,,4,1059,1.31,1.12,3.25,,1.32
2022-02-25,2022-03-04,Other system,Anaphylaxis*,581,175,28,3,,1,788,1.07,0.77,1.00,,0.99
2022-02-25,2022-03-04,Other system,COVID-19*,319,16,2,3,,17,357,0.59,0.07,N/A,,0.45
2022-02-25,2022-03-04,Other system,Multisystem inflammatory syndrome,12,1,0,0,,0,13,0.02,N/A,N/A,,0.02
2022-02-25,2022-03-04,Other system,Subtotal n (%),912,192,30,6,,18,1158,1.68,0.84,1.07,,1.45
2022-02-25,2022-03-04,Pregnancy outcomes,Fetal growth restriction,5,0,0,0,,0,5,N/A,N/A,N/A,,N/A
2022-02-25,2022-03-04,Pregnancy outcomes,Spontaneous abortion,58,12,1,0,,0,71,0.11,0.05,N/A,,0.09
2022-02-25,2022-03-04,Pregnancy outcomes,Subtotal n (%),63,12,1,0,,0,76,0.12,0.05,N/A,,0.10
2022-02-25,2022-03-04,Respiratory system,Acute respiratory distress syndrome,3,2,0,0,,0,5,N/A,N/A,N/A,,N/A
2022-02-25,2022-03-04,Respiratory system,Subtotal n (%),3,2,0,0,,0,5,N/A,N/A,N/A,,N/A
2022-02-25,2022-03-04,"Skin and mucous membrane, bone and joints system",Chilblains,18,5,2,0,,0,25,0.03,N/A,N/A,,0.03
2022-02-25,2022-03-04,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),27,13,2,0,,0,42,0.05,0.06,N/A,,0.05
2022-02-25,2022-03-04,"Skin and mucous membrane, bone and joints system",Subtotal n (%),45,18,4,0,,0,67,0.08,0.08,N/A,,0.08
2022-02-25,2022-03-04,All AESI categories,TOTAL,3924,1518,688,10,,38,6178,7.23,6.68,24.60,,7.73
2022-03-04,2022-03-11,Auto-immune diseases,Guillain-Barré Syndrome,56,27,39,0,,1,123,0.10,0.12,1.39,,0.15
2022-03-04,2022-03-11,Auto-immune diseases,Thrombocytopenia (low blood platelets),125,48,81,1,,1,256,0.23,0.21,2.90,,0.32
2022-03-04,2022-03-11,Auto-immune diseases,Subtotal n (%),181,75,120,1,,2,379,0.33,0.33,4.29,,0.47
2022-03-04,2022-03-11,Cardiovascular system,Cardiac arrest,21,15,6,0,,0,42,0.04,0.07,N/A,,0.05
2022-03-04,2022-03-11,Cardiovascular system,Cardiac failure,26,16,4,0,,1,47,0.05,0.07,N/A,,0.06
2022-03-04,2022-03-11,Cardiovascular system,Myocardial infarction (heart attack),74,21,6,1,,3,105,0.14,0.09,N/A,,0.13
2022-03-04,2022-03-11,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),1192,656,32,1,,5,1886,2.18,2.88,1.14,,2.35
2022-03-04,2022-03-11,Cardiovascular system,Subtotal n (%),1313,708,48,2,,9,2051,2.41,3.10,1.72,,2.55
2022-03-04,2022-03-11,Circulatory system,Cerebral venous (sinus) thrombosis,5,3,12,0,,0,20,N/A,N/A,0.43,,0.02
2022-03-04,2022-03-11,Circulatory system,Cerebral thrombosis ,6,3,1,0,,0,10,N/A,N/A,N/A,,0.01
2022-03-04,2022-03-11,Circulatory system,Cutaneous vasculitis,21,8,8,0,,0,37,0.04,N/A,N/A,,0.05
2022-03-04,2022-03-11,Circulatory system,Deep vein thrombosis,168,66,66,0,,0,300,0.31,0.29,2.36,,0.37
2022-03-04,2022-03-11,Circulatory system,Embolism,5,4,7,0,,0,16,N/A,N/A,N/A,,0.02
2022-03-04,2022-03-11,Circulatory system,Haemorrhage (bleeding),40,14,10,0,,3,67,0.07,0.06,0.36,,0.08
2022-03-04,2022-03-11,Circulatory system,Pulmonary embolism,221,91,126,1,,0,439,0.40,0.40,4.51,,0.55
2022-03-04,2022-03-11,Circulatory system,Thrombosis (blood clot),169,41,87,0,,2,299,0.31,0.18,3.11,,0.37
2022-03-04,2022-03-11,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),27,13,68,0,,0,108,0.05,0.06,2.43,,0.13
2022-03-04,2022-03-11,Circulatory system,Subtotal n (%),662,243,385,1,,5,1296,1.21,1.07,13.77,,1.61
2022-03-04,2022-03-11,Hepato-gastrointestinal and renal system,Acute kidney injury,32,19,6,0,,0,57,0.06,0.08,N/A,,0.07
2022-03-04,2022-03-11,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),12,5,1,0,,0,18,0.02,N/A,N/A,,0.02
2022-03-04,2022-03-11,Hepato-gastrointestinal and renal system,Liver injury,24,11,3,0,,0,38,0.04,0.05,N/A,,0.05
2022-03-04,2022-03-11,Hepato-gastrointestinal and renal system,Subtotal n (%),68,35,10,0,,0,113,0.12,0.15,0.36,,0.14
2022-03-04,2022-03-11,Nerves and central nervous system,Bell's Palsy/facial paralysis*,584,206,55,0,,0,845,1.07,0.90,1.97,,1.05
2022-03-04,2022-03-11,Nerves and central nervous system,Cerebrovascular accident (stroke),124,53,36,0,,4,217,0.23,0.23,1.29,,0.27
2022-03-04,2022-03-11,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),8,5,0,0,,0,13,N/A,N/A,N/A,,0.02
2022-03-04,2022-03-11,Nerves and central nervous system,Subtotal n (%),716,264,91,0,,4,1075,1.31,1.16,3.25,,1.34
2022-03-04,2022-03-11,Other system,Anaphylaxis*,584,179,28,3,,1,795,1.07,0.78,1.00,,0.99
2022-03-04,2022-03-11,Other system,COVID-19*,330,18,2,3,,17,370,0.60,0.08,N/A,,0.46
2022-03-04,2022-03-11,Other system,Multisystem inflammatory syndrome,12,1,0,0,,0,13,0.02,N/A,N/A,,0.02
2022-03-04,2022-03-11,Other system,Subtotal n (%),926,198,30,6,,18,1178,1.70,0.87,1.07,,1.47
2022-03-04,2022-03-11,Pregnancy outcomes,Fetal growth restriction,5,0,0,0,,0,5,N/A,N/A,N/A,,N/A
2022-03-04,2022-03-11,Pregnancy outcomes,Spontaneous abortion,59,13,1,0,,0,73,0.11,0.06,N/A,,0.09
2022-03-04,2022-03-11,Pregnancy outcomes,Subtotal n (%),64,13,1,0,,0,78,0.12,0.06,N/A,,0.10
2022-03-04,2022-03-11,Respiratory system,Acute respiratory distress syndrome,3,2,0,0,,0,5,N/A,N/A,N/A,,N/A
2022-03-04,2022-03-11,Respiratory system,Subtotal n (%),3,2,0,0,,0,5,N/A,N/A,N/A,,N/A
2022-03-04,2022-03-11,"Skin and mucous membrane, bone and joints system",Chilblains,18,5,2,0,,0,25,0.03,N/A,N/A,,0.03
2022-03-04,2022-03-11,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),27,15,2,0,,0,44,0.05,0.07,N/A,,0.05
2022-03-04,2022-03-11,"Skin and mucous membrane, bone and joints system",Subtotal n (%),45,20,4,0,,0,69,0.08,0.09,N/A,,0.09
2022-03-04,2022-03-11,All AESI categories,TOTAL,3978,1558,689,10,,38,6273,7.29,6.83,24.64,,7.81
2022-03-11,2022-03-18,Auto-immune diseases,Guillain-Barré Syndrome,56,27,39,0,,1,123,0.10,0.12,1.39,,0.15
2022-03-11,2022-03-18,Auto-immune diseases,Thrombocytopenia (low blood platelets),124,48,81,1,,1,255,0.23,0.21,2.90,,0.32
2022-03-11,2022-03-18,Auto-immune diseases,Subtotal n (%),180,75,120,1,,2,378,0.33,0.33,4.29,,0.47
2022-03-11,2022-03-18,Cardiovascular system,Cardiac arrest,22,15,6,0,,0,43,0.04,0.07,N/A,,0.05
2022-03-11,2022-03-18,Cardiovascular system,Cardiac failure,26,17,4,0,,1,48,0.05,0.07,N/A,,0.06
2022-03-11,2022-03-18,Cardiovascular system,Myocardial infarction (heart attack),74,22,6,1,,3,106,0.14,0.10,N/A,,0.13
2022-03-11,2022-03-18,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),1213,664,33,1,,5,1916,2.21,2.91,1.18,,2.38
2022-03-11,2022-03-18,Cardiovascular system,Subtotal n (%),1335,718,49,2,,9,2113,2.44,3.14,1.75,,2.62
2022-03-11,2022-03-18,Circulatory system,Cerebral venous (sinus) thrombosis,6,4,13,0,,0,23,N/A,N/A,0.46,,0.03
2022-03-11,2022-03-18,Circulatory system,Cerebral thrombosis ,6,3,1,0,,0,10,N/A,N/A,N/A,,0.01
2022-03-11,2022-03-18,Circulatory system,Cutaneous vasculitis,21,8,8,0,,0,37,0.04,N/A,N/A,,0.05
2022-03-11,2022-03-18,Circulatory system,Deep vein thrombosis,168,68,66,0,,0,302,0.31,0.30,2.36,,0.37
2022-03-11,2022-03-18,Circulatory system,Embolism,5,4,7,0,,0,16,N/A,N/A,N/A,,0.02
2022-03-11,2022-03-18,Circulatory system,Haemorrhage (bleeding),41,14,10,0,,3,68,0.07,0.06,0.36,,0.08
2022-03-11,2022-03-18,Circulatory system,Pulmonary embolism,222,92,126,1,,0,441,0.41,0.40,4.50,,0.55
2022-03-11,2022-03-18,Circulatory system,Thrombosis (blood clot),169,43,88,0,,2,302,0.31,0.19,3.15,,0.37
2022-03-11,2022-03-18,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),29,13,69,0,,0,111,0.05,0.06,2.47,,0.14
2022-03-11,2022-03-18,Circulatory system,Subtotal n (%),667,249,388,1,,5,1310,1.22,1.09,13.87,,1.63
2022-03-11,2022-03-18,Hepato-gastrointestinal and renal system,Acute kidney injury,34,19,6,0,,0,59,0.06,0.08,N/A,,0.07
2022-03-11,2022-03-18,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),12,5,1,0,,0,18,0.02,N/A,N/A,,0.02
2022-03-11,2022-03-18,Hepato-gastrointestinal and renal system,Liver injury,24,11,3,0,,0,38,0.04,0.05,N/A,,0.05
2022-03-11,2022-03-18,Hepato-gastrointestinal and renal system,Subtotal n (%),70,35,10,0,,0,115,0.13,0.15,0.36,,0.14
2022-03-11,2022-03-18,Nerves and central nervous system,Bell's Palsy/facial paralysis*,591,214,55,0,,1,861,1.08,0.94,1.97,,1.07
2022-03-11,2022-03-18,Nerves and central nervous system,Cerebrovascular accident (stroke),128,53,36,0,,4,221,0.23,0.23,1.29,,0.27
2022-03-11,2022-03-18,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),8,5,0,0,,0,13,N/A,N/A,N/A,,0.02
2022-03-11,2022-03-18,Nerves and central nervous system,Subtotal n (%),727,272,91,0,,5,1095,1.33,1.19,3.25,,1.36
2022-03-11,2022-03-18,Other system,Anaphylaxis*,585,179,28,3,,1,796,1.07,0.78,1.00,,0.99
2022-03-11,2022-03-18,Other system,COVID-19*,339,18,2,3,,17,379,0.62,0.08,N/A,,0.47
2022-03-11,2022-03-18,Other system,Multisystem inflammatory syndrome,12,1,0,0,,0,13,0.02,N/A,N/A,,0.02
2022-03-11,2022-03-18,Other system,Subtotal n (%),936,198,30,6,,18,1188,1.71,0.87,1.07,,1.47
2022-03-11,2022-03-18,Pregnancy outcomes,Fetal growth restriction,5,0,0,0,,0,5,N/A,N/A,N/A,,N/A
2022-03-11,2022-03-18,Pregnancy outcomes,Spontaneous abortion,59,13,1,0,,0,73,0.11,0.06,N/A,,0.09
2022-03-11,2022-03-18,Pregnancy outcomes,Subtotal n (%),64,13,1,0,,0,78,0.12,0.06,N/A,,0.10
2022-03-11,2022-03-18,Respiratory system,Acute respiratory distress syndrome,5,4,0,0,,0,9,N/A,N/A,N/A,,N/A
2022-03-11,2022-03-18,Respiratory system,Subtotal n (%),5,4,0,0,,0,9,N/A,N/A,N/A,,N/A
2022-03-11,2022-03-18,"Skin and mucous membrane, bone and joints system",Chilblains,17,5,2,0,,0,24,0.03,N/A,N/A,,0.03
2022-03-11,2022-03-18,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),28,15,2,0,,0,45,0.05,0.07,N/A,,0.06
2022-03-11,2022-03-18,"Skin and mucous membrane, bone and joints system",Subtotal n (%),45,20,4,0,,0,69,0.08,0.09,N/A,,0.09
2022-03-11,2022-03-18,All AESI categories,TOTAL,4029,1584,693,10,,39,6355,7.36,6.93,24.78,,7.89
2022-03-18,2022-03-25,Auto-immune diseases,Guillain-Barré Syndrome,56,28,39,0,,1,124,0.10,0.12,1.39,,0.15
2022-03-18,2022-03-25,Auto-immune diseases,Thrombocytopenia (low blood platelets),130,50,85,1,,1,267,0.24,0.22,3.04,,0.33
2022-03-18,2022-03-25,Auto-immune diseases,Subtotal n (%),186,78,124,1,,2,391,0.34,0.34,4.43,,0.48
2022-03-18,2022-03-25,Cardiovascular system,Cardiac arrest,22,15,6,0,,0,43,0.04,0.07,N/A,,0.05
2022-03-18,2022-03-25,Cardiovascular system,Cardiac failure,27,16,4,0,,1,48,0.05,0.07,N/A,,0.06
2022-03-18,2022-03-25,Cardiovascular system,Myocardial infarction (heart attack),74,23,6,1,,3,107,0.13,0.10,N/A,,0.13
2022-03-18,2022-03-25,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),1224,669,34,1,,5,1933,2.23,2.92,1.22,,2.39
2022-03-18,2022-03-25,Cardiovascular system,Subtotal n (%),1347,723,50,2,,9,2131,2.45,3.16,1.79,,2.64
2022-03-18,2022-03-25,Circulatory system,Cerebral venous (sinus) thrombosis,6,4,13,0,,0,23,N/A,N/A,0.46,,0.03
2022-03-18,2022-03-25,Circulatory system,Cerebral thrombosis ,6,3,1,0,,0,10,N/A,N/A,N/A,,0.01
2022-03-18,2022-03-25,Circulatory system,Cutaneous vasculitis,22,8,8,0,,0,38,0.04,N/A,N/A,,0.05
2022-03-18,2022-03-25,Circulatory system,Deep vein thrombosis,170,70,70,0,,0,310,0.31,0.31,2.50,,0.38
2022-03-18,2022-03-25,Circulatory system,Embolism,5,4,7,0,,0,16,N/A,N/A,N/A,,0.02
2022-03-18,2022-03-25,Circulatory system,Haemorrhage (bleeding),41,14,10,0,,3,68,0.07,0.06,0.36,,0.08
2022-03-18,2022-03-25,Circulatory system,Pulmonary embolism,225,93,130,1,,0,449,0.41,0.41,4.65,,0.56
2022-03-18,2022-03-25,Circulatory system,Thrombosis (blood clot),173,43,90,0,,2,308,0.31,0.19,3.22,,0.38
2022-03-18,2022-03-25,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),30,13,69,0,,0,112,0.05,0.06,2.47,,0.14
2022-03-18,2022-03-25,Circulatory system,Subtotal n (%),678,252,398,1,,5,1334,1.23,1.10,14.23,,1.65
2022-03-18,2022-03-25,Hepato-gastrointestinal and renal system,Acute kidney injury,35,20,7,0,,0,62,0.06,0.09,N/A,,0.08
2022-03-18,2022-03-25,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),12,5,1,0,,0,18,0.02,N/A,N/A,,0.02
2022-03-18,2022-03-25,Hepato-gastrointestinal and renal system,Liver injury,24,11,3,0,,0,38,0.04,0.05,N/A,,0.05
2022-03-18,2022-03-25,Hepato-gastrointestinal and renal system,Subtotal n (%),71,36,11,0,,0,118,0.13,0.16,0.39,,0.15
2022-03-18,2022-03-25,Nerves and central nervous system,Bell's Palsy/facial paralysis*,596,217,55,0,,1,869,1.08,0.95,1.97,,1.08
2022-03-18,2022-03-25,Nerves and central nervous system,Cerebrovascular accident (stroke),129,53,36,0,,4,222,0.23,0.23,1.29,,0.27
2022-03-18,2022-03-25,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),10,5,0,0,,0,15,N/A,N/A,N/A,,0.02
2022-03-18,2022-03-25,Nerves and central nervous system,Subtotal n (%),735,275,91,0,,5,1106,1.34,1.20,3.25,,1.37
2022-03-18,2022-03-25,Other system,Anaphylaxis*,599,184,29,3,,1,816,1.09,0.80,1.04,,1.01
2022-03-18,2022-03-25,Other system,COVID-19*,346,20,2,4,,17,389,0.63,0.09,N/A,,0.48
2022-03-18,2022-03-25,Other system,Multisystem inflammatory syndrome,12,1,0,0,,0,13,0.02,N/A,N/A,,0.02
2022-03-18,2022-03-25,Other system,Subtotal n (%),957,205,31,7,,18,1218,1.74,0.90,1.11,,1.51
2022-03-18,2022-03-25,Pregnancy outcomes,Fetal growth restriction,5,0,0,0,,0,5,N/A,N/A,N/A,,N/A
2022-03-18,2022-03-25,Pregnancy outcomes,Spontaneous abortion,59,13,1,0,,0,73,0.11,0.06,N/A,,0.09
2022-03-18,2022-03-25,Pregnancy outcomes,Subtotal n (%),64,13,1,0,,0,78,0.12,0.06,N/A,,0.10
2022-03-18,2022-03-25,Respiratory system,Acute respiratory distress syndrome,5,4,0,0,,0,9,N/A,N/A,N/A,,N/A
2022-03-18,2022-03-25,Respiratory system,Subtotal n (%),5,4,0,0,,0,9,N/A,N/A,N/A,,N/A
2022-03-18,2022-03-25,"Skin and mucous membrane, bone and joints system",Chilblains,18,5,2,0,,0,25,0.03,N/A,N/A,,0.03
2022-03-18,2022-03-25,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),29,15,3,0,,0,47,0.05,0.07,N/A,,0.06
2022-03-18,2022-03-25,"Skin and mucous membrane, bone and joints system",Subtotal n (%),47,20,5,0,,0,72,0.09,0.09,N/A,,0.09
2022-03-18,2022-03-25,All AESI categories,TOTAL,4090,1606,711,11,,39,6457,7.44,7.02,25.42,,8.00
2022-03-25,2022-04-01,Auto-immune diseases,Guillain-Barré Syndrome,57,28,39,0,,1,125,0.10,0.12,1.39,,0.15
2022-03-25,2022-04-01,Auto-immune diseases,Thrombocytopenia (low blood platelets),132,49,84,1,,1,267,0.24,0.21,3.00,,0.33
2022-03-25,2022-04-01,Auto-immune diseases,Subtotal n (%),189,77,123,1,,2,392,0.34,0.34,4.40,,0.48
2022-03-25,2022-04-01,Cardiovascular system,Cardiac arrest,22,15,6,0,,0,43,0.04,0.07,N/A,,0.05
2022-03-25,2022-04-01,Cardiovascular system,Cardiac failure,27,16,4,0,,1,48,0.05,0.07,N/A,,0.06
2022-03-25,2022-04-01,Cardiovascular system,Myocardial infarction (heart attack),75,23,6,1,,3,108,0.14,0.10,N/A,,0.13
2022-03-25,2022-04-01,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),1253,676,35,1,,6,1971,2.27,2.95,1.25,,2.43
2022-03-25,2022-04-01,Cardiovascular system,Subtotal n (%),1377,730,51,2,,10,2170,2.50,3.18,1.82,,2.68
2022-03-25,2022-04-01,Circulatory system,Cerebral venous (sinus) thrombosis,5,4,13,0,,0,22,N/A,N/A,0.46,,0.03
2022-03-25,2022-04-01,Circulatory system,Cerebral thrombosis ,4,3,1,0,,0,8,N/A,N/A,N/A,,N/A
2022-03-25,2022-04-01,Circulatory system,Cutaneous vasculitis,22,8,8,0,,0,38,0.04,N/A,N/A,,0.05
2022-03-25,2022-04-01,Circulatory system,Deep vein thrombosis,165,69,72,0,,0,306,0.30,0.30,2.57,,0.38
2022-03-25,2022-04-01,Circulatory system,Embolism,5,4,7,0,,0,16,N/A,N/A,N/A,,0.02
2022-03-25,2022-04-01,Circulatory system,Haemorrhage (bleeding),41,14,10,0,,3,68,0.07,0.06,0.36,,0.08
2022-03-25,2022-04-01,Circulatory system,Pulmonary embolism,228,94,122,0,,1,445,0.41,0.41,4.36,,0.55
2022-03-25,2022-04-01,Circulatory system,Thrombosis (blood clot),157,41,91,0,,3,292,0.28,0.18,3.25,,0.36
2022-03-25,2022-04-01,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),30,13,69,0,,0,112,0.05,0.06,2.47,,0.14
2022-03-25,2022-04-01,Circulatory system,Subtotal n (%),657,250,393,0,,7,1307,1.19,1.09,14.05,,1.61
2022-03-25,2022-04-01,Hepato-gastrointestinal and renal system,Acute kidney injury,35,20,7,0,,0,62,0.06,0.09,N/A,,0.08
2022-03-25,2022-04-01,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),12,5,1,0,,0,18,0.02,N/A,N/A,,0.02
2022-03-25,2022-04-01,Hepato-gastrointestinal and renal system,Liver injury,24,11,3,0,,0,38,0.04,0.05,N/A,,0.05
2022-03-25,2022-04-01,Hepato-gastrointestinal and renal system,Subtotal n (%),71,36,11,0,,0,118,0.13,0.16,0.39,,0.15
2022-03-25,2022-04-01,Nerves and central nervous system,Bell's Palsy/facial paralysis*,598,218,55,1,,0,872,1.09,0.95,1.97,,1.08
2022-03-25,2022-04-01,Nerves and central nervous system,Cerebrovascular accident (stroke),129,55,36,0,,5,225,0.23,0.24,1.29,,0.28
2022-03-25,2022-04-01,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),10,5,0,0,,0,15,0.02,N/A,N/A,,0.02
2022-03-25,2022-04-01,Nerves and central nervous system,Subtotal n (%),737,278,91,1,,5,1112,1.34,1.21,3.25,,1.37
2022-03-25,2022-04-01,Other system,Anaphylaxis*,600,186,29,3,,1,819,1.09,0.81,1.04,,1.01
2022-03-25,2022-04-01,Other system,COVID-19*,352,22,2,4,,19,399,0.64,N/A,N/A,,0.49
2022-03-25,2022-04-01,Other system,Multisystem inflammatory syndrome,12,1,0,0,,0,13,0.02,N/A,N/A,,0.02
2022-03-25,2022-04-01,Other system,Subtotal n (%),964,209,31,7,,20,1231,1.75,0.91,1.11,,1.52
2022-03-25,2022-04-01,Pregnancy outcomes,Fetal growth restriction,5,0,0,0,,0,5,N/A,N/A,N/A,,N/A
2022-03-25,2022-04-01,Pregnancy outcomes,Spontaneous abortion,59,13,1,0,,0,73,0.11,0.06,N/A,,0.09
2022-03-25,2022-04-01,Pregnancy outcomes,Subtotal n (%),64,13,1,0,,0,78,0.12,0.06,N/A,,0.10
2022-03-25,2022-04-01,Respiratory system,Acute respiratory distress syndrome,5,4,0,0,,0,9,N/A,N/A,N/A,,N/A
2022-03-25,2022-04-01,Respiratory system,Subtotal n (%),5,4,0,0,,0,9,N/A,N/A,N/A,,N/A
2022-03-25,2022-04-01,"Skin and mucous membrane, bone and joints system",Chilblains,18,6,2,0,,0,26,0.03,N/A,N/A,,0.03
2022-03-25,2022-04-01,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),29,15,3,0,,0,47,0.05,0.07,N/A,,0.06
2022-03-25,2022-04-01,"Skin and mucous membrane, bone and joints system",Subtotal n (%),47,21,5,0,,0,73,0.09,0.09,N/A,,0.09
2022-03-25,2022-04-01,All AESI categories,TOTAL,4111,1618,706,11,,44,6490,7.46,7.06,25.24,,8.02
2022-04-01,2022-04-08,Auto-immune diseases,Guillain-Barré Syndrome,57,28,39,0,,1,125,0.10,0.12,1.39,,0.15
2022-04-01,2022-04-08,Auto-immune diseases,Thrombocytopenia (low blood platelets),133,49,84,1,,1,268,0.24,0.21,3.00,,0.33
2022-04-01,2022-04-08,Auto-immune diseases,Subtotal n (%),190,77,123,1,,2,393,0.34,0.34,4.40,,0.48
2022-04-01,2022-04-08,Cardiovascular system,Cardiac arrest,22,15,6,0,,0,43,0.04,0.07,N/A,,0.05
2022-04-01,2022-04-08,Cardiovascular system,Cardiac failure,27,16,4,0,,1,48,0.05,0.07,N/A,,0.06
2022-04-01,2022-04-08,Cardiovascular system,Myocardial infarction (heart attack),77,24,6,1,,3,111,0.14,0.10,N/A,,0.14
2022-04-01,2022-04-08,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),1273,683,35,1,,7,1999,2.30,2.98,1.25,,2.46
2022-04-01,2022-04-08,Cardiovascular system,Subtotal n (%),1399,738,51,2,,11,2201,2.53,3.21,1.82,,2.71
2022-04-01,2022-04-08,Circulatory system,Cerebral venous (sinus) thrombosis,6,4,14,0,,0,24,N/A,N/A,0.50,,0.03
2022-04-01,2022-04-08,Circulatory system,Cerebral thrombosis ,4,3,1,0,,0,8,N/A,N/A,N/A,,N/A
2022-04-01,2022-04-08,Circulatory system,Cutaneous vasculitis,22,8,8,0,,0,38,0.04,N/A,N/A,,0.05
2022-04-01,2022-04-08,Circulatory system,Deep vein thrombosis,166,69,72,0,,0,307,0.30,0.30,2.57,,0.38
2022-04-01,2022-04-08,Circulatory system,Embolism,5,5,7,0,,0,17,N/A,N/A,N/A,,0.02
2022-04-01,2022-04-08,Circulatory system,Haemorrhage (bleeding),42,14,10,0,,3,69,0.08,0.06,N/A,,0.09
2022-04-01,2022-04-08,Circulatory system,Pulmonary embolism,230,94,132,0,,1,457,0.42,0.41,4.72,,0.56
2022-04-01,2022-04-08,Circulatory system,Thrombosis (blood clot),157,42,91,0,,3,293,0.28,0.18,3.25,,0.36
2022-04-01,2022-04-08,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),30,13,69,0,,0,112,0.05,0.06,2.47,,0.14
2022-04-01,2022-04-08,Circulatory system,Subtotal n (%),662,252,404,0,,7,1325,1.20,1.10,14.44,,1.63
2022-04-01,2022-04-08,Hepato-gastrointestinal and renal system,Acute kidney injury,36,20,7,0,,0,63,0.07,0.09,N/A,,0.08
2022-04-01,2022-04-08,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),12,5,1,0,,0,18,0.02,N/A,N/A,,0.02
2022-04-01,2022-04-08,Hepato-gastrointestinal and renal system,Liver injury,24,11,3,0,,0,38,0.04,0.05,N/A,,0.05
2022-04-01,2022-04-08,Hepato-gastrointestinal and renal system,Subtotal n (%),72,36,11,0,,0,119,0.13,0.16,0.39,,0.15
2022-04-01,2022-04-08,Nerves and central nervous system,Bell's Palsy/facial paralysis*,599,220,55,1,,1,876,1.08,0.96,1.97,,1.08
2022-04-01,2022-04-08,Nerves and central nervous system,Cerebrovascular accident (stroke),131,55,36,0,,5,227,0.24,0.24,1.29,,0.28
2022-04-01,2022-04-08,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),10,5,0,0,,0,15,0.02,N/A,N/A,,0.02
2022-04-01,2022-04-08,Nerves and central nervous system,Subtotal n (%),740,280,91,1,,6,1118,1.34,1.22,3.25,,1.38
2022-04-01,2022-04-08,Other system,Anaphylaxis*,606,186,29,3,,1,825,1.10,0.81,1.04,,1.02
2022-04-01,2022-04-08,Other system,COVID-19*,359,24,4,5,,20,412,0.65,N/A,N/A,,0.51
2022-04-01,2022-04-08,Other system,Multisystem inflammatory syndrome,10,1,0,0,,1,12,0.02,N/A,N/A,,0.01
2022-04-01,2022-04-08,Other system,Subtotal n (%),975,211,33,8,,22,1249,1.76,0.92,1.18,,1.54
2022-04-01,2022-04-08,Pregnancy outcomes,Fetal growth restriction,5,0,0,0,,0,5,N/A,N/A,N/A,,N/A
2022-04-01,2022-04-08,Pregnancy outcomes,Spontaneous abortion,59,14,1,0,,0,74,0.11,0.06,N/A,,0.09
2022-04-01,2022-04-08,Pregnancy outcomes,Subtotal n (%),64,14,1,0,,0,79,0.12,0.06,N/A,,0.10
2022-04-01,2022-04-08,Respiratory system,Acute respiratory distress syndrome,5,4,0,0,,0,9,N/A,N/A,N/A,,N/A
2022-04-01,2022-04-08,Respiratory system,Subtotal n (%),5,4,0,0,,0,9,N/A,N/A,N/A,,N/A
2022-04-01,2022-04-08,"Skin and mucous membrane, bone and joints system",Chilblains,18,6,2,0,,0,26,0.03,N/A,N/A,,0.03
2022-04-01,2022-04-08,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),29,15,3,0,,0,47,0.05,0.07,N/A,,0.06
2022-04-01,2022-04-08,"Skin and mucous membrane, bone and joints system",Subtotal n (%),47,21,5,0,,0,73,0.09,0.09,N/A,,0.09
2022-04-01,2022-04-08,All AESI categories,TOTAL,4154,1633,719,12,,48,6566,7.52,7.11,25.70,,8.09
2022-04-08,2022-04-19,Auto-immune diseases,Guillain-Barré Syndrome,57,28,39,0,,1,125,0.10,0.12,1.39,,0.15
2022-04-08,2022-04-19,Auto-immune diseases,Thrombocytopenia (low blood platelets),133,49,85,1,,1,269,0.24,0.21,3.04,,0.33
2022-04-08,2022-04-19,Auto-immune diseases,Subtotal n (%),190,77,124,1,,2,394,0.34,0.33,4.43,,0.48
2022-04-08,2022-04-19,Cardiovascular system,Cardiac arrest,22,15,6,0,,0,43,0.04,0.07,N/A,,0.05
2022-04-08,2022-04-19,Cardiovascular system,Cardiac failure,29,16,4,0,,1,50,0.05,0.07,N/A,,0.06
2022-04-08,2022-04-19,Cardiovascular system,Myocardial infarction (heart attack),76,25,6,1,,3,111,0.14,0.11,N/A,,0.14
2022-04-08,2022-04-19,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),1285,686,35,1,,7,2014,2.32,2.98,1.25,,2.48
2022-04-08,2022-04-19,Cardiovascular system,Subtotal n (%),1412,742,51,2,,11,2218,2.55,3.23,1.82,,2.73
2022-04-08,2022-04-19,Circulatory system,Cerebral venous (sinus) thrombosis,6,4,14,0,,0,24,N/A,N/A,0.50,,0.03
2022-04-08,2022-04-19,Circulatory system,Cerebral thrombosis ,4,4,1,0,,0,9,N/A,N/A,N/A,,N/A
2022-04-08,2022-04-19,Circulatory system,Cutaneous vasculitis,22,8,8,0,,0,38,0.04,N/A,N/A,,0.05
2022-04-08,2022-04-19,Circulatory system,Deep vein thrombosis,168,69,72,0,,0,309,0.30,0.30,2.57,,0.38
2022-04-08,2022-04-19,Circulatory system,Embolism,5,5,7,0,,0,17,N/A,N/A,N/A,,0.02
2022-04-08,2022-04-19,Circulatory system,Haemorrhage (bleeding),42,14,10,0,,3,69,0.08,0.06,0.36,,0.08
2022-04-08,2022-04-19,Circulatory system,Pulmonary embolism,232,95,132,0,,1,460,0.42,0.41,4.72,,0.57
2022-04-08,2022-04-19,Circulatory system,Thrombosis (blood clot),158,43,91,0,,3,295,0.28,0.19,3.25,,0.36
2022-04-08,2022-04-19,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),30,13,69,0,,0,112,0.05,0.06,2.47,,0.14
2022-04-08,2022-04-19,Circulatory system,Subtotal n (%),667,255,404,0,,7,1333,1.20,1.11,14.44,,1.64
2022-04-08,2022-04-19,Hepato-gastrointestinal and renal system,Acute kidney injury,36,21,7,0,,0,64,0.06,0.09,N/A,,0.08
2022-04-08,2022-04-19,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),13,5,1,0,,0,19,0.02,N/A,N/A,,0.02
2022-04-08,2022-04-19,Hepato-gastrointestinal and renal system,Liver injury,24,12,3,0,,0,39,0.04,0.05,N/A,,0.05
2022-04-08,2022-04-19,Hepato-gastrointestinal and renal system,Subtotal n (%),73,38,11,0,,0,122,0.13,0.17,0.39,,0.15
2022-04-08,2022-04-19,Nerves and central nervous system,Bell's Palsy/facial paralysis*,599,220,55,1,,1,876,1.08,0.96,1.97,,1.08
2022-04-08,2022-04-19,Nerves and central nervous system,Cerebrovascular accident (stroke),131,55,36,0,,5,227,0.24,0.24,1.29,,0.28
2022-04-08,2022-04-19,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),10,5,0,0,,0,15,0.02,N/A,N/A,,0.02
2022-04-08,2022-04-19,Nerves and central nervous system,Subtotal n (%),740,280,91,1,,6,1118,1.33,1.22,3.25,,1.37
2022-04-08,2022-04-19,Other system,Anaphylaxis*,609,186,29,3,,1,828,1.10,0.81,1.04,,1.02
2022-04-08,2022-04-19,Other system,COVID-19*,370,25,4,7,,20,426,0.67,0.11,N/A,,0.52
2022-04-08,2022-04-19,Other system,Multisystem inflammatory syndrome,9,1,0,0,,1,11,N/A,N/A,N/A,,0.01
2022-04-08,2022-04-19,Other system,Subtotal n (%),988,212,33,10,,22,1265,1.78,0.92,1.18,,1.56
2022-04-08,2022-04-19,Pregnancy outcomes,Fetal growth restriction,5,0,0,0,,0,5,N/A,N/A,N/A,,N/A
2022-04-08,2022-04-19,Pregnancy outcomes,Spontaneous abortion,59,13,1,0,,0,73,0.11,0.06,N/A,,0.09
2022-04-08,2022-04-19,Pregnancy outcomes,Subtotal n (%),64,13,1,0,,0,78,0.12,0.06,N/A,,0.10
2022-04-08,2022-04-19,Respiratory system,Acute respiratory distress syndrome,5,4,0,0,,0,9,N/A,N/A,N/A,,N/A
2022-04-08,2022-04-19,Respiratory system,Subtotal n (%),5,4,0,0,,0,9,N/A,N/A,N/A,,N/A
2022-04-08,2022-04-19,"Skin and mucous membrane, bone and joints system",Chilblains,18,6,2,0,,0,26,0.03,N/A,N/A,,0.03
2022-04-08,2022-04-19,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),29,16,3,0,,0,48,0.05,0.07,N/A,,0.06
2022-04-08,2022-04-19,"Skin and mucous membrane, bone and joints system",Subtotal n (%),47,22,5,0,,0,74,0.08,0.10,N/A,,0.09
2022-04-08,2022-04-19,All AESI categories,TOTAL,4186,1643,720,14,,48,6611,7.55,7.14,25.74,,8.13
2022-04-15,2022-04-29,Auto-immune diseases,Guillain-Barré Syndrome,59,29,39,0,,1,128,0.11,0.13,1.39,,0.16
2022-04-15,2022-04-29,Auto-immune diseases,Thrombocytopenia (low blood platelets),134,50,85,1,,1,271,0.24,0.22,3.02,,0.33
2022-04-15,2022-04-29,Auto-immune diseases,Subtotal n (%),193,79,124,1,,2,399,0.35,0.34,4.41,,0.49
2022-04-15,2022-04-29,Cardiovascular system,Cardiac arrest,22,15,6,0,,0,43,0.04,0.06,0.21,,0.05
2022-04-15,2022-04-29,Cardiovascular system,Cardiac failure,30,16,4,0,,1,51,0.05,0.07,0.14,,0.06
2022-04-15,2022-04-29,Cardiovascular system,Myocardial infarction (heart attack),76,25,6,1,,3,111,0.14,0.11,0.21,,0.14
2022-04-15,2022-04-29,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart),1302,698,35,1,,8,2044,2.34,3.02,1.24,,2.50
2022-04-15,2022-04-29,Cardiovascular system,Subtotal n (%),1430,754,51,2,,12,2249,2.57,3.27,1.81,,2.75
2022-04-15,2022-04-29,Circulatory system,Cerebral venous (sinus) thrombosis,6,4,14,0,,0,24,0.01,0.02,0.50,,0.03
2022-04-15,2022-04-29,Circulatory system,Cerebral thrombosis ,5,4,1,0,,0,10,0.01,0.02,0.04,,0.01
2022-04-15,2022-04-29,Circulatory system,Cutaneous vasculitis,22,8,8,0,,0,38,0.04,0.03,0.28,,0.05
2022-04-15,2022-04-29,Circulatory system,Deep vein thrombosis,168,70,72,0,,0,310,0.30,0.30,2.56,,0.38
2022-04-15,2022-04-29,Circulatory system,Embolism,5,5,7,0,,0,17,0.01,0.02,0.25,,0.02
2022-04-15,2022-04-29,Circulatory system,Haemorrhage (bleeding),43,14,10,0,,3,70,0.08,0.06,0.36,,0.09
2022-04-15,2022-04-29,Circulatory system,Pulmonary embolism,234,96,132,0,,0,462,0.42,0.42,4.69,,0.57
2022-04-15,2022-04-29,Circulatory system,Thrombosis (blood clot),159,43,91,0,,3,296,0.29,0.19,3.24,,0.36
2022-04-15,2022-04-29,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets),30,13,71,0,,0,114,0.05,0.06,2.52,,0.14
2022-04-15,2022-04-29,Circulatory system,Subtotal n (%),672,257,406,0,,6,1341,1.21,1.11,14.44,,1.64
2022-04-15,2022-04-29,Hepato-gastrointestinal and renal system,Acute kidney injury,36,21,7,0,,0,64,0.06,0.09,0.25,,0.08
2022-04-15,2022-04-29,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),13,5,1,0,,0,19,0.02,0.02,0.04,,0.02
2022-04-15,2022-04-29,Hepato-gastrointestinal and renal system,Liver injury,24,12,3,0,,0,39,0.04,0.05,0.11,,0.05
2022-04-15,2022-04-29,Hepato-gastrointestinal and renal system,Subtotal n (%),73,38,11,0,,0,122,0.13,0.16,0.39,,0.15
2022-04-15,2022-04-29,Nerves and central nervous system,Bell's Palsy/facial paralysis*,599,221,55,1,,1,877,1.08,0.96,1.96,,1.07
2022-04-15,2022-04-29,Nerves and central nervous system,Cerebrovascular accident (stroke),131,54,36,0,,6,227,0.24,0.23,1.28,,0.28
2022-04-15,2022-04-29,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),10,5,0,0,,0,15,0.02,0.02,0.00,,0.02
2022-04-15,2022-04-29,Nerves and central nervous system,Subtotal n (%),740,280,91,1,,7,1119,1.33,1.21,3.24,,1.37
2022-04-15,2022-04-29,Other system,Anaphylaxis*,610,186,29,3,,1,829,1.09,0.81,1.03,,1.01
2022-04-15,2022-04-29,Other system,COVID-19*,387,26,4,7,,20,444,0.69,0.11,0.14,,0.54
2022-04-15,2022-04-29,Other system,Multisystem inflammatory syndrome,9,1,0,0,,2,12,0.02,0.00,0.00,,0.01
2022-04-15,2022-04-29,Other system,Subtotal n (%),1006,213,33,10,,23,1285,1.81,0.92,1.17,,1.57
2022-04-15,2022-04-29,Pregnancy outcomes,Fetal growth restriction,5,0,0,0,,0,5,0.01,0.00,0.00,,0.01
2022-04-15,2022-04-29,Pregnancy outcomes,Spontaneous abortion,59,13,1,0,,0,73,0.11,0.06,0.04,,0.09
2022-04-15,2022-04-29,Pregnancy outcomes,Subtotal n (%),64,13,1,0,,0,78,0.11,0.06,0.04,,0.10
2022-04-15,2022-04-29,Respiratory system,Acute respiratory distress syndrome,5,4,0,0,,0,9,0.01,0.02,0.00,,0.01
2022-04-15,2022-04-29,Respiratory system,Subtotal n (%),5,4,0,0,,0,9,0.01,0.02,0.00,,0.01
2022-04-15,2022-04-29,"Skin and mucous membrane, bone and joints system",Chilblains,18,6,2,0,,0,26,0.03,0.03,0.07,,0.03
2022-04-15,2022-04-29,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),28,16,3,0,,0,47,0.05,0.07,0.11,,0.06
2022-04-15,2022-04-29,"Skin and mucous membrane, bone and joints system",Subtotal n (%),46,22,5,0,,0,73,0.08,0.10,0.18,,0.09
2022-04-15,2022-04-29,All AESI categories,TOTAL,4229,1660,722,14,,50,6675,7.59,7.19,25.67,,8.17
2022-04-29,2022-05-13,Auto-immune diseases,Guillain-Barré Syndrome BCD 1-3,8,5,7,0,,0,20,N/A,N/A,N/A,,0.02
2022-04-29,2022-05-13,Auto-immune diseases,Guillain-Barré Syndrome BCD 4,53,24,32,0,,1,110,0.09,0.10,1.14,,0.13
2022-04-29,2022-05-13,Auto-immune diseases,Thrombocytopenia (low blood platelets) BCD 1-3,93,31,51,1,,1,177,0.16,0.13,1.81,,0.21
2022-04-29,2022-05-13,Auto-immune diseases,Thrombocytopenia (low blood platelets) BCD 4,41,19,34,0,,0,94,0.07,0.08,1.21,,0.11
2022-04-29,2022-05-13,Auto-immune diseases,Subtotal n (%),195,79,124,1,,2,401,0.35,0.34,4.41,,0.48
2022-04-29,2022-05-13,Cardiovascular system,Cardiac arrest,23,15,6,0,,0,44,0.04,0.06,N/A,,0.05
2022-04-29,2022-05-13,Cardiovascular system,Cardiac failure,30,17,4,0,,1,52,0.05,0.07,N/A,,0.06
2022-04-29,2022-05-13,Cardiovascular system,Myocardial infarction (heart attack),79,25,6,1,,3,114,0.14,0.11,N/A,,0.14
2022-04-29,2022-05-13,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart) BCD 1-3,635,405,17,0,,2,1059,1.13,1.73,0.60,,1.28
2022-04-29,2022-05-13,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart) BCD 4,685,306,17,2,,6,1016,1.21,1.31,0.60,,1.23
2022-04-29,2022-05-13,Cardiovascular system,Subtotal n (%),1452,768,50,3,,12,2285,2.57,3.28,1.78,,2.76
2022-04-29,2022-05-13,Circulatory system,Cerebral venous (sinus) thrombosis,7,4,15,0,,0,26,N/A,N/A,0.53,,0.03
2022-04-29,2022-05-13,Circulatory system,Cerebral thrombosis ,5,4,1,0,,0,10,N/A,N/A,N/A,,0.01
2022-04-29,2022-05-13,Circulatory system,Cutaneous vasculitis,22,8,8,0,,0,38,0.04,N/A,N/A,,0.05
2022-04-29,2022-05-13,Circulatory system,Deep vein thrombosis,169,71,73,1,,0,314,0.30,0.30,2.60,,0.38
2022-04-29,2022-05-13,Circulatory system,Embolism,5,5,7,0,,0,17,N/A,N/A,N/A,,0.02
2022-04-29,2022-05-13,Circulatory system,Haemorrhage (bleeding),44,14,10,0,,3,71,0.08,0.06,0.36,,0.09
2022-04-29,2022-05-13,Circulatory system,Pulmonary embolism,237,96,135,1,,1,470,0.42,0.41,4.80,,0.57
2022-04-29,2022-05-13,Circulatory system,Thrombosis (blood clot),166,42,90,0,,3,301,0.29,0.18,3.20,,0.36
2022-04-29,2022-05-13,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets) BCD 1-3,28,11,63,0,,0,102,0.05,0.02,2.24,,0.12
2022-04-29,2022-05-13,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets) BCD 4,2,2,8,0,,0,12,N/A,N/A,N/A,,0.01
2022-04-29,2022-05-13,Circulatory system,Subtotal n (%),685,257,410,2,,7,1361,1.21,1.10,14.58,,1.65
2022-04-29,2022-05-13,Hepato-gastrointestinal and renal system,Acute kidney injury,36,21,7,0,,0,64,0.06,0.09,N/A,,0.08
2022-04-29,2022-05-13,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),13,5,1,0,,0,19,0.02,N/A,N/A,,0.02
2022-04-29,2022-05-13,Hepato-gastrointestinal and renal system,Liver injury,24,12,3,0,,0,39,0.04,0.05,N/A,,0.05
2022-04-29,2022-05-13,Hepato-gastrointestinal and renal system,Subtotal n (%),73,38,11,0,,0,122,0.13,0.16,0.39,,0.15
2022-04-29,2022-05-13,Nerves and central nervous system,Bell's Palsy/facial paralysis* BCD 1-3,113,32,11,0,,1,157,0.20,0.06,0.39,,0.19
2022-04-29,2022-05-13,Nerves and central nervous system,Bell's Palsy/facial paralysis* BCD 4,487,191,44,2,,0,724,0.86,0.34,1.56,,0.88
2022-04-29,2022-05-13,Nerves and central nervous system,Cerebrovascular accident (stroke),136,56,36,0,,6,234,0.24,0.24,1.28,,0.28
2022-04-29,2022-05-13,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),10,5,0,0,,0,15,0.02,N/A,N/A,,0.02
2022-04-29,2022-05-13,Nerves and central nervous system,Subtotal n (%),746,284,91,2,,7,1130,1.32,1.21,3.24,,1.37
2022-04-29,2022-05-13,Other system,Anaphylaxis*,619,186,29,3,,1,838,1.10,0.79,1.03,,1.01
2022-04-29,2022-05-13,Other system,COVID-19*,424,31,4,7,,21,487,0.75,0.13,N/A,,0.59
2022-04-29,2022-05-13,Other system,Multisystem inflammatory syndrome,11,1,0,0,,2,14,0.02,N/A,N/A,,0.02
2022-04-29,2022-05-13,Other system,Subtotal n (%),1054,218,33,10,,24,1339,1.87,0.93,1.17,,1.62
2022-04-29,2022-05-13,Pregnancy outcomes,Fetal growth restriction,5,0,0,0,,0,5,N/A,N/A,N/A,,N/A
2022-04-29,2022-05-13,Pregnancy outcomes,Spontaneous abortion,61,16,1,0,,0,78,0.11,0.07,N/A,,0.09
2022-04-29,2022-05-13,Pregnancy outcomes,Subtotal n (%),66,16,1,0,,0,83,0.12,0.07,N/A,,0.10
2022-04-29,2022-05-13,Respiratory system,Acute respiratory distress syndrome,5,4,0,0,,0,9,N/A,N/A,N/A,,N/A
2022-04-29,2022-05-13,Respiratory system,Subtotal n (%),5,4,0,0,,0,9,N/A,N/A,N/A,,N/A
2022-04-29,2022-05-13,"Skin and mucous membrane, bone and joints system",Chilblains,20,6,2,0,,0,28,0.04,N/A,N/A,,0.03
2022-04-29,2022-05-13,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),28,17,3,0,,0,48,0.05,0.07,N/A,,0.06
2022-04-29,2022-05-13,"Skin and mucous membrane, bone and joints system",Subtotal n (%),48,23,5,0,,0,76,0.09,0.10,N/A,,0.09
2022-04-29,2022-05-13,All AESI categories,TOTAL,4324,1687,725,18,,52,6806,7.67,7.21,25.78,,8.23
2022-05-13,2022-05-30,Auto-immune diseases,Guillain-Barré Syndrome BCD 1-3,8,5,7,0,,0,20,N/A,N/A,N/A,,0.02
2022-05-13,2022-05-30,Auto-immune diseases,Guillain-Barré Syndrome BCD 4,52,25,32,0,,1,110,0.09,0.11,1.14,,0.13
2022-05-13,2022-05-30,Auto-immune diseases,Thrombocytopenia (low blood platelets) BCD 1-3,94,31,51,1,,1,178,0.16,0.13,1.81,,0.21
2022-05-13,2022-05-30,Auto-immune diseases,Thrombocytopenia (low blood platelets) BCD 4,41,18,34,0,,0,93,0.07,0.08,1.21,,0.11
2022-05-13,2022-05-30,Auto-immune diseases,Subtotal n (%),195,79,124,1,,2,401,0.34,0.33,4.41,,0.48
2022-05-13,2022-05-30,Cardiovascular system,Cardiac arrest,23,15,6,0,,0,44,0.04,0.06,N/A,,0.05
2022-05-13,2022-05-30,Cardiovascular system,Cardiac failure,29,18,4,0,,1,52,0.05,0.08,N/A,,0.06
2022-05-13,2022-05-30,Cardiovascular system,Myocardial infarction (heart attack),80,25,6,1,,3,115,0.14,0.11,N/A,,0.14
2022-05-13,2022-05-30,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart) BCD 1-3,639,405,15,0,,2,1061,1.12,1.71,0.53,,1.27
2022-05-13,2022-05-30,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart) BCD 4,692,309,17,1,,6,1025,1.21,1.30,0.60,,1.23
2022-05-13,2022-05-30,Cardiovascular system,Subtotal n (%),1463,772,48,2,,12,2297,2.57,3.26,1.71,,2.75
2022-05-13,2022-05-30,Circulatory system,Cerebral venous (sinus) thrombosis,7,4,15,0,,0,26,N/A,N/A,0.53,,0.03
2022-05-13,2022-05-30,Circulatory system,Cerebral thrombosis ,5,4,1,0,,0,10,N/A,N/A,N/A,,0.01
2022-05-13,2022-05-30,Circulatory system,Cutaneous vasculitis,22,9,8,0,,0,39,0.04,N/A,N/A,,0.05
2022-05-13,2022-05-30,Circulatory system,Deep vein thrombosis,170,74,73,1,,0,318,0.30,0.31,2.60,,0.38
2022-05-13,2022-05-30,Circulatory system,Embolism,5,5,7,0,,0,17,N/A,N/A,N/A,,0.02
2022-05-13,2022-05-30,Circulatory system,Haemorrhage (bleeding),44,14,10,0,,3,71,0.08,0.06,0.36,,0.08
2022-05-13,2022-05-30,Circulatory system,Pulmonary embolism,241,100,135,1,,1,478,0.42,0.42,4.80,,0.57
2022-05-13,2022-05-30,Circulatory system,Thrombosis (blood clot),169,44,90,0,,3,306,0.30,0.19,3.20,,0.37
2022-05-13,2022-05-30,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets) BCD 1-3,28,11,64,0,,0,103,0.05,0.05,2.28,,0.12
2022-05-13,2022-05-30,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets) BCD 4,2,2,7,0,,0,11,N/A,N/A,N/A,,0.01
2022-05-13,2022-05-30,Circulatory system,Subtotal n (%),693,267,410,2,,7,1379,1.22,1.13,14.58,,1.65
2022-05-13,2022-05-30,Hepato-gastrointestinal and renal system,Acute kidney injury,35,23,7,0,,0,65,0.06,0.10,N/A,,0.08
2022-05-13,2022-05-30,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),13,5,1,0,,0,19,0.02,N/A,N/A,,0.02
2022-05-13,2022-05-30,Hepato-gastrointestinal and renal system,Liver injury,23,11,3,0,,0,37,0.04,0.05,N/A,,0.04
2022-05-13,2022-05-30,Hepato-gastrointestinal and renal system,Subtotal n (%),71,39,11,0,,0,121,0.12,0.16,0.39,,0.14
2022-05-13,2022-05-30,Nerves and central nervous system,Bell's Palsy/facial paralysis* BCD 1-3,117,33,12,0,,1,163,0.21,0.14,0.43,,0.19
2022-05-13,2022-05-30,Nerves and central nervous system,Bell's Palsy/facial paralysis* BCD 4,496,193,43,2,,0,734,0.87,0.81,1.53,,0.88
2022-05-13,2022-05-30,Nerves and central nervous system,Cerebrovascular accident (stroke),136,57,37,0,,6,236,0.24,0.24,1.32,,0.28
2022-05-13,2022-05-30,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),10,5,0,0,,0,15,0.02,N/A,N/A,,0.02
2022-05-13,2022-05-30,Nerves and central nervous system,Subtotal n (%),759,288,92,2,,7,1148,1.33,1.21,3.27,,1.37
2022-05-13,2022-05-30,Other system,Anaphylaxis*,620,187,29,3,,1,840,1.09,0.79,1.03,,1.00
2022-05-13,2022-05-30,Other system,COVID-19*,443,35,4,8,,23,513,0.78,0.15,N/A,,0.61
2022-05-13,2022-05-30,Other system,Multisystem inflammatory syndrome,12,1,0,0,,2,15,0.02,N/A,N/A,,0.02
2022-05-13,2022-05-30,Other system,Subtotal n (%),1075,223,33,11,,26,1368,1.89,0.94,1.17,,1.64
2022-05-13,2022-05-30,Pregnancy outcomes,Fetal growth restriction,5,0,0,0,,0,5,N/A,N/A,N/A,,N/A
2022-05-13,2022-05-30,Pregnancy outcomes,Spontaneous abortion,63,16,1,0,,0,80,0.11,0.07,N/A,,0.10
2022-05-13,2022-05-30,Pregnancy outcomes,Subtotal n (%),68,16,1,0,,0,85,0.12,0.07,N/A,,0.10
2022-05-13,2022-05-30,Respiratory system,Acute respiratory distress syndrome,5,4,0,0,,0,9,N/A,N/A,N/A,,N/A
2022-05-13,2022-05-30,Respiratory system,Subtotal n (%),5,4,0,0,,0,9,N/A,N/A,N/A,,N/A
2022-05-13,2022-05-30,"Skin and mucous membrane, bone and joints system",Chilblains,21,6,2,0,,0,29,0.04,N/A,N/A,,0.03
2022-05-13,2022-05-30,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),28,17,3,0,,0,48,0.05,0.07,N/A,,0.06
2022-05-13,2022-05-30,"Skin and mucous membrane, bone and joints system",Subtotal n (%),49,23,5,0,,0,77,0.09,0.10,N/A,,0.09
2022-05-13,2022-05-30,All AESI categories,TOTAL,4378,1711,724,18,,54,6885,7.68,7.22,25.74,,8.23
2022-05-27,2022-06-24,Auto-immune diseases,Guillain-Barré Syndrome BCD 1-3,8,5,7,0,0,0,20,N/A,N/A,N/A,N/A,0.02
2022-05-27,2022-06-24,Auto-immune diseases,Thrombocytopenia (low blood platelets) BCD 1-3,94,31,51,1,0,1,178,0.16,0.13,1.81,N/A,0.21
2022-05-27,2022-06-24,Auto-immune diseases,Subtotal n (%),102,36,58,1,0,1,198,0.18,0.15,2.06,N/A,0.23
2022-05-27,2022-06-24,Cardiovascular system,Cardiac arrest,23,15,6,0,0,0,44,0.04,0.06,N/A,N/A,0.05
2022-05-27,2022-06-24,Cardiovascular system,Cardiac failure,28,18,4,0,0,1,51,0.05,0.08,N/A,N/A,0.06
2022-05-27,2022-06-24,Cardiovascular system,Myocardial infarction (heart attack),83,25,8,1,0,4,121,0.14,0.10,N/A,N/A,0.14
2022-05-27,2022-06-24,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart) BCD 1-3,643,407,15,0,0,2,1067,1.12,1.70,0.53,N/A,1.27
2022-05-27,2022-06-24,Cardiovascular system,Subtotal n (%),777,465,33,1,0,7,1283,1.35,1.94,1.17,N/A,1.52
2022-05-27,2022-06-24,Circulatory system,Cerebral venous (sinus) thrombosis,7,4,15,0,0,0,26,N/A,N/A,0.53,N/A,0.03
2022-05-27,2022-06-24,Circulatory system,Cerebral thrombosis ,9,4,1,0,0,2,16,N/A,N/A,N/A,N/A,0.02
2022-05-27,2022-06-24,Circulatory system,Cutaneous vasculitis,22,9,8,0,0,0,39,0.04,N/A,N/A,N/A,0.05
2022-05-27,2022-06-24,Circulatory system,Deep vein thrombosis,173,77,74,1,0,0,325,0.30,0.32,2.63,N/A,0.39
2022-05-27,2022-06-24,Circulatory system,Embolism,6,5,7,0,0,0,18,N/A,N/A,N/A,N/A,0.02
2022-05-27,2022-06-24,Circulatory system,Haemorrhage (bleeding),45,15,10,0,0,3,73,0.08,0.06,0.36,N/A,0.09
2022-05-27,2022-06-24,Circulatory system,Pulmonary embolism,244,100,136,1,0,1,482,0.42,0.42,4.83,N/A,0.57
2022-05-27,2022-06-24,Circulatory system,Thrombosis (blood clot),173,46,90,0,0,3,312,0.30,0.19,3.20,N/A,0.37
2022-05-27,2022-06-24,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets) BCD 1-3,28,12,64,0,0,0,104,0.05,0.05,2.28,N/A,0.12
2022-05-27,2022-06-24,Circulatory system,Subtotal n (%),707,272,405,2,0,9,1395,1.23,1.14,14.40,N/A,1.65
2022-05-27,2022-06-24,Hepato-gastrointestinal and renal system,Acute kidney injury,35,23,7,0,0,0,65,0.06,0.10,N/A,N/A,0.08
2022-05-27,2022-06-24,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),13,5,1,0,0,0,19,0.02,N/A,N/A,N/A,0.02
2022-05-27,2022-06-24,Hepato-gastrointestinal and renal system,Liver injury,23,11,3,0,0,0,37,0.04,0.05,N/A,N/A,0.04
2022-05-27,2022-06-24,Hepato-gastrointestinal and renal system,Subtotal n (%),71,39,11,0,0,0,121,0.12,0.16,0.39,N/A,0.14
2022-05-27,2022-06-24,Nerves and central nervous system,Bell's Palsy/facial paralysis* BCD 1-3,117,33,12,0,0,1,163,0.20,0.14,0.43,N/A,0.19
2022-05-27,2022-06-24,Nerves and central nervous system,Cerebrovascular accident (stroke),138,57,37,0,0,6,238,0.24,0.24,1.32,N/A,0.28
2022-05-27,2022-06-24,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),10,5,0,0,0,0,15,0.02,N/A,N/A,N/A,0.02
2022-05-27,2022-06-24,Nerves and central nervous system,Subtotal n (%),265,95,49,0,0,7,416,0.46,0.40,1.74,N/A,0.49
2022-05-27,2022-06-24,Other system,Anaphylaxis*,622,187,29,3,1,1,843,1.08,0.78,1.03,N/A,1.00
2022-05-27,2022-06-24,Other system,COVID-19*,476,40,5,8,0,27,556,0.83,0.17,N/A,N/A,0.66
2022-05-27,2022-06-24,Other system,Multisystem inflammatory syndrome,15,1,0,0,0,2,18,0.03,N/A,N/A,N/A,0.02
2022-05-27,2022-06-24,Other system,Subtotal n (%),1113,228,34,11,1,30,1417,1.94,0.95,1.21,51.42,1.68
2022-05-27,2022-06-24,Pregnancy outcomes,Fetal growth restriction,5,0,0,0,0,0,5,N/A,N/A,N/A,N/A,N/A
2022-05-27,2022-06-24,Pregnancy outcomes,Spontaneous abortion,63,16,1,0,0,0,80,0.11,0.07,N/A,N/A,0.09
2022-05-27,2022-06-24,Pregnancy outcomes,Subtotal n (%),68,16,1,0,0,0,85,0.12,0.07,N/A,N/A,0.10
2022-05-27,2022-06-24,Respiratory system,Acute respiratory distress syndrome,5,4,0,0,0,0,9,N/A,N/A,N/A,N/A,N/A
2022-05-27,2022-06-24,Respiratory system,Subtotal n (%),5,4,0,0,0,0,9,N/A,N/A,N/A,N/A,N/A
2022-05-27,2022-06-24,"Skin and mucous membrane, bone and joints system",Chilblains,21,6,2,0,0,0,29,0.04,N/A,N/A,N/A,0.03
2022-05-27,2022-06-24,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),29,18,3,0,0,0,50,0.05,0.08,N/A,N/A,0.06
2022-05-27,2022-06-24,"Skin and mucous membrane, bone and joints system",Subtotal n (%),50,24,5,0,0,0,79,0.09,0.10,N/A,N/A,0.09
2022-05-27,2022-06-24,All AESI categories,TOTAL,3158,1179,596,15,1,54,5003,5.49,4.92,21.19,70.11,5.93
2022-06-24,2022-07-08,Auto-immune diseases,Guillain-Barré Syndrome BCD 1-3,8,5,8,0,0,0,21,N/A,N/A,N/A,N/A,0.02
2022-06-24,2022-07-08,Auto-immune diseases,Thrombocytopenia (low blood platelets) BCD 1-3,95,33,51,1,0,1,181,0.16,0.14,1.81,N/A,0.21
2022-06-24,2022-07-08,Auto-immune diseases,Subtotal n (%),103,38,59,1,0,1,202,0.18,0.16,2.10,N/A,0.24
2022-06-24,2022-07-08,Cardiovascular system,Cardiac arrest,25,16,6,0,0,0,47,0.04,0.07,N/A,N/A,0.06
2022-06-24,2022-07-08,Cardiovascular system,Cardiac failure,29,19,4,0,0,2,54,0.05,0.08,N/A,N/A,0.06
2022-06-24,2022-07-08,Cardiovascular system,Myocardial infarction (heart attack),84,26,9,1,0,4,124,0.14,0.11,N/A,N/A,0.15
2022-06-24,2022-07-08,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart) BCD 1-3,657,414,15,0,0,11,1097,1.13,1.70,0.53,N/A,1.29
2022-06-24,2022-07-08,Cardiovascular system,Subtotal n (%),795,475,34,1,0,17,1322,1.37,1.96,1.21,N/A,1.55
2022-06-24,2022-07-08,Circulatory system,Cerebral venous (sinus) thrombosis,7,4,15,0,0,0,26,N/A,N/A,0.53,N/A,0.03
2022-06-24,2022-07-08,Circulatory system,Cerebral thrombosis ,9,4,1,0,0,2,16,N/A,N/A,N/A,N/A,0.02
2022-06-24,2022-07-08,Circulatory system,Cutaneous vasculitis,23,10,9,0,0,0,42,0.04,0.04,N/A,N/A,0.05
2022-06-24,2022-07-08,Circulatory system,Deep vein thrombosis,178,81,77,1,0,0,337,0.31,0.33,2.74,N/A,0.40
2022-06-24,2022-07-08,Circulatory system,Embolism,5,5,7,0,0,0,17,N/A,N/A,N/A,N/A,0.02
2022-06-24,2022-07-08,Circulatory system,Haemorrhage (bleeding),46,14,10,0,0,3,73,0.08,0.06,0.36,N/A,0.09
2022-06-24,2022-07-08,Circulatory system,Pulmonary embolism,258,106,137,1,0,2,504,0.44,0.44,4.87,N/A,0.59
2022-06-24,2022-07-08,Circulatory system,Thrombosis (blood clot),174,46,92,0,0,3,315,0.30,0.19,3.27,N/A,0.37
2022-06-24,2022-07-08,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets) BCD 1-3,29,12,64,0,0,0,105,0.05,0.05,2.28,N/A,0.12
2022-06-24,2022-07-08,Circulatory system,Subtotal n (%),729,282,412,2,0,10,1435,1.25,1.16,14.65,N/A,1.68
2022-06-24,2022-07-08,Hepato-gastrointestinal and renal system,Acute kidney injury,40,24,7,0,0,0,71,0.07,0.10,N/A,N/A,0.08
2022-06-24,2022-07-08,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),15,5,1,0,0,0,21,0.03,N/A,N/A,N/A,0.02
2022-06-24,2022-07-08,Hepato-gastrointestinal and renal system,Liver injury,23,11,3,0,0,0,37,0.04,0.05,N/A,N/A,0.04
2022-06-24,2022-07-08,Hepato-gastrointestinal and renal system,Subtotal n (%),78,40,11,0,0,0,129,0.13,0.16,0.39,N/A,0.15
2022-06-24,2022-07-08,Nerves and central nervous system,Bell's Palsy/facial paralysis* BCD 1-3,118,34,12,0,0,1,165,0.20,0.14,0.43,N/A,0.19
2022-06-24,2022-07-08,Nerves and central nervous system,Cerebrovascular accident (stroke),139,60,39,0,0,6,244,0.24,0.25,1.39,N/A,0.29
2022-06-24,2022-07-08,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),10,5,0,0,0,0,15,0.02,N/A,N/A,N/A,0.02
2022-06-24,2022-07-08,Nerves and central nervous system,Subtotal n (%),267,99,51,0,0,7,424,0.46,0.41,1.81,N/A,0.50
2022-06-24,2022-07-08,Other system,Anaphylaxis*,627,188,29,4,2,1,851,1.08,0.77,1.03,N/A,1.00
2022-06-24,2022-07-08,Other system,COVID-19*,515,48,6,8,0,34,611,0.89,0.20,N/A,N/A,0.72
2022-06-24,2022-07-08,Other system,Multisystem inflammatory syndrome,15,1,0,0,0,2,18,0.03,N/A,N/A,N/A,0.02
2022-06-24,2022-07-08,Other system,Subtotal n (%),1157,237,35,12,2,37,1480,1.99,0.98,1.24,54.49,1.73
2022-06-24,2022-07-08,Pregnancy outcomes,Fetal growth restriction,5,0,0,0,0,0,5,N/A,N/A,N/A,N/A,N/A
2022-06-24,2022-07-08,Pregnancy outcomes,Spontaneous abortion,64,19,1,0,0,0,84,0.11,0.08,N/A,N/A,0.10
2022-06-24,2022-07-08,Pregnancy outcomes,Subtotal n (%),69,19,1,0,0,0,89,0.12,0.08,N/A,N/A,0.10
2022-06-24,2022-07-08,Respiratory system,Acute respiratory distress syndrome,5,4,0,0,0,0,9,N/A,N/A,N/A,N/A,N/A
2022-06-24,2022-07-08,Respiratory system,Subtotal n (%),5,4,0,0,0,0,9,N/A,N/A,N/A,N/A,N/A
2022-06-24,2022-07-08,"Skin and mucous membrane, bone and joints system",Chilblains,21,6,2,0,0,0,29,0.04,N/A,N/A,N/A,0.03
2022-06-24,2022-07-08,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),29,18,3,0,0,0,50,0.05,0.07,N/A,N/A,0.06
2022-06-24,2022-07-08,"Skin and mucous membrane, bone and joints system",Subtotal n (%),50,24,5,0,0,0,79,0.09,0.10,N/A,N/A,0.09
2022-06-24,2022-07-08,All AESI categories,TOTAL,3253,1218,608,16,2,72,5169,5.60,5.01,21.62,72.65,6.06
2022-07-22,2022-08-05,Auto-immune diseases,Guillain-Barré Syndrome BCD 1-3,8,5,8,0,0,0,21,N/A,N/A,N/A,N/A,0.02
2022-07-22,2022-08-05,Auto-immune diseases,Thrombocytopenia (low blood platelets) BCD 1-3,100,34,51,1,0,1,187,0.17,0.14,1.81,N/A,0.22
2022-07-22,2022-08-05,Auto-immune diseases,Subtotal n (%),108,39,59,1,0,1,208,0.18,0.16,2.10,N/A,0.24
2022-07-22,2022-08-05,Cardiovascular system,Cardiac arrest,26,17,6,0,0,0,49,0.04,0.07,N/A,N/A,0.06
2022-07-22,2022-08-05,Cardiovascular system,Cardiac failure,29,19,4,0,0,3,55,0.05,0.08,N/A,N/A,0.06
2022-07-22,2022-08-05,Cardiovascular system,Myocardial infarction (heart attack),86,29,9,1,0,4,129,0.15,0.12,N/A,N/A,0.15
2022-07-22,2022-08-05,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart) BCD 1-3,664,418,15,0,0,9,1106,1.13,1.70,0.53,N/A,1.28
2022-07-22,2022-08-05,Cardiovascular system,Subtotal n (%),805,483,34,1,0,16,1339,1.37,1.96,1.21,N/A,1.55
2022-07-22,2022-08-05,Circulatory system,Cerebral venous (sinus) thrombosis,7,4,15,0,0,0,26,N/A,N/A,0.53,N/A,0.03
2022-07-22,2022-08-05,Circulatory system,Cerebral thrombosis ,9,4,1,0,0,2,16,N/A,N/A,N/A,N/A,0.02
2022-07-22,2022-08-05,Circulatory system,Cutaneous vasculitis,23,10,10,0,0,0,43,0.04,0.04,0.36,N/A,0.05
2022-07-22,2022-08-05,Circulatory system,Deep vein thrombosis,179,86,77,1,0,0,343,0.30,0.35,2.74,N/A,0.40
2022-07-22,2022-08-05,Circulatory system,Embolism,5,5,7,0,0,0,17,N/A,N/A,N/A,N/A,0.02
2022-07-22,2022-08-05,Circulatory system,Haemorrhage (bleeding),47,14,10,0,0,3,74,0.08,0.06,0.36,N/A,0.09
2022-07-22,2022-08-05,Circulatory system,Pulmonary embolism,263,111,138,1,0,2,515,0.45,0.45,4.91,N/A,0.60
2022-07-22,2022-08-05,Circulatory system,Thrombosis (blood clot),174,48,92,0,0,3,317,0.30,0.20,3.27,N/A,0.37
2022-07-22,2022-08-05,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets) BCD 1-3,29,12,64,0,0,0,105,0.05,0.05,2.28,N/A,0.12
2022-07-22,2022-08-05,Circulatory system,Subtotal n (%),736,294,414,2,0,10,1456,1.25,1.20,14.72,N/A,1.69
2022-07-22,2022-08-05,Hepato-gastrointestinal and renal system,Acute kidney injury,40,26,7,0,0,0,73,0.07,0.11,N/A,N/A,0.08
2022-07-22,2022-08-05,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),15,6,1,0,0,0,22,0.03,N/A,N/A,N/A,0.03
2022-07-22,2022-08-05,Hepato-gastrointestinal and renal system,Liver injury,24,11,3,0,0,0,38,0.04,0.04,N/A,N/A,0.04
2022-07-22,2022-08-05,Hepato-gastrointestinal and renal system,Subtotal n (%),79,43,11,0,0,0,133,0.13,0.17,0.39,N/A,0.15
2022-07-22,2022-08-05,Nerves and central nervous system,Bell's Palsy/facial paralysis* BCD 1-3,117,34,13,0,0,1,165,0.20,0.14,0.46,N/A,0.19
2022-07-22,2022-08-05,Nerves and central nervous system,Cerebrovascular accident (stroke),140,62,39,0,0,7,248,0.24,0.25,1.39,N/A,0.29
2022-07-22,2022-08-05,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),10,5,0,0,0,0,15,0.02,N/A,N/A,N/A,0.02
2022-07-22,2022-08-05,Nerves and central nervous system,Subtotal n (%),267,101,52,0,0,8,428,0.45,0.41,1.85,N/A,0.50
2022-07-22,2022-08-05,Other system,Anaphylaxis*,637,190,29,4,2,1,863,1.08,0.77,1.03,N/A,1.00
2022-07-22,2022-08-05,Other system,COVID-19*,546,55,9,9,0,39,658,0.93,0.22,N/A,N/A,0.76
2022-07-22,2022-08-05,Other system,Multisystem inflammatory syndrome,18,1,0,0,0,1,20,0.03,N/A,N/A,N/A,0.02
2022-07-22,2022-08-05,Other system,Subtotal n (%),1201,246,38,13,2,41,1541,2.05,1.00,1.35,58.17,1.79
2022-07-22,2022-08-05,Pregnancy outcomes,Fetal growth restriction,5,0,0,0,0,0,5,N/A,N/A,N/A,N/A,N/A
2022-07-22,2022-08-05,Pregnancy outcomes,Spontaneous abortion,64,20,1,0,0,0,85,0.11,0.08,N/A,N/A,0.10
2022-07-22,2022-08-05,Pregnancy outcomes,Subtotal n (%),69,20,1,0,0,0,90,0.12,0.08,N/A,N/A,0.10
2022-07-22,2022-08-05,Respiratory system,Acute respiratory distress syndrome,5,4,0,0,0,0,9,N/A,N/A,N/A,N/A,N/A
2022-07-22,2022-08-05,Respiratory system,Subtotal n (%),5,4,0,0,0,0,9,N/A,N/A,N/A,N/A,N/A
2022-07-22,2022-08-05,"Skin and mucous membrane, bone and joints system",Chilblains,21,6,2,0,0,0,29,0.04,N/A,N/A,N/A,0.03
2022-07-22,2022-08-05,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),29,19,4,0,0,0,52,0.05,0.08,N/A,N/A,0.06
2022-07-22,2022-08-05,"Skin and mucous membrane, bone and joints system",Subtotal n (%),50,25,6,0,0,0,81,0.09,0.10,N/A,N/A,0.09
2022-07-22,2022-08-05,All AESI categories,TOTAL,3320,1255,615,17,2,76,5285,5.65,5.10,21.86,76.07,6.13
2022-08-19,2022-09-02,Auto-immune diseases,Guillain-Barré Syndrome BCD 1-3,8,6,8,0,0,0,22,N/A,N/A,N/A,N/A,0.03
2022-08-19,2022-09-02,Auto-immune diseases,Thrombocytopenia (low blood platelets) BCD 1-3,100,33,51,1,0,1,186,0.17,0.13,1.81,N/A,0.21
2022-08-19,2022-09-02,Auto-immune diseases,Subtotal n (%),108,39,59,1,0,1,208,0.18,0.16,2.10,N/A,0.24
2022-08-19,2022-09-02,Cardiovascular system,Cardiac arrest,26,18,6,0,0,0,50,0.04,0.07,N/A,N/A,0.06
2022-08-19,2022-09-02,Cardiovascular system,Cardiac failure,29,20,4,0,0,4,57,0.05,0.08,N/A,N/A,0.07
2022-08-19,2022-09-02,Cardiovascular system,Myocardial infarction (heart attack),88,30,9,1,0,5,133,0.15,0.12,N/A,N/A,0.15
2022-08-19,2022-09-02,Cardiovascular system,Myocarditis/Pericarditis (inflammation of the heart muscle and lining around the heart) BCD 1-3,668,422,15,0,0,9,1114,1.12,1.70,0.53,N/A,1.28
2022-08-19,2022-09-02,Cardiovascular system,Subtotal n (%),811,490,34,1,0,18,1354,1.37,1.97,1.21,N/A,1.55
2022-08-19,2022-09-02,Circulatory system,Cerebral venous (sinus) thrombosis,7,4,17,0,0,0,28,N/A,N/A,0.60,N/A,0.03
2022-08-19,2022-09-02,Circulatory system,Cerebral thrombosis,9,4,1,0,0,2,16,N/A,N/A,N/A,N/A,0.02
2022-08-19,2022-09-02,Circulatory system,Cutaneous vasculitis,23,10,10,0,0,0,43,0.04,0.04,0.36,N/A,0.05
2022-08-19,2022-09-02,Circulatory system,Deep vein thrombosis,181,88,77,1,0,0,347,0.30,0.35,2.74,N/A,0.40
2022-08-19,2022-09-02,Circulatory system,Embolism,5,5,8,0,0,1,19,N/A,N/A,N/A,N/A,0.02
2022-08-19,2022-09-02,Circulatory system,Haemorrhage (bleeding),47,14,10,0,0,3,74,0.08,0.06,0.36,N/A,0.08
2022-08-19,2022-09-02,Circulatory system,Pulmonary embolism,269,115,138,1,1,2,526,0.45,0.46,4.90,N/A,0.60
2022-08-19,2022-09-02,Circulatory system,Thrombosis (blood clot),174,49,95,0,0,3,321,0.29,0.20,3.38,N/A,0.37
2022-08-19,2022-09-02,Circulatory system,Thrombosis with thrombocytopenia syndrome (blood clot with low platelets) BCD 1-3,29,12,64,0,0,0,105,0.05,0.05,2.27,N/A,0.12
2022-08-19,2022-09-02,Circulatory system,Subtotal n (%),744,301,420,2,1,11,1479,1.25,1.21,14.93,N/A,1.70
2022-08-19,2022-09-02,Hepato-gastrointestinal and renal system,Acute kidney injury,40,27,7,0,0,0,74,0.07,0.11,N/A,N/A,0.08
2022-08-19,2022-09-02,Hepato-gastrointestinal and renal system,Glomerulonephritis (kidney inflammation) and nephrotic syndrome (kidney disorder),17,5,1,0,0,0,23,0.03,N/A,N/A,N/A,0.03
2022-08-19,2022-09-02,Hepato-gastrointestinal and renal system,Liver injury,24,11,3,0,0,0,38,0.04,0.04,N/A,N/A,0.04
2022-08-19,2022-09-02,Hepato-gastrointestinal and renal system,Subtotal n (%),81,43,11,0,0,0,135,0.14,0.17,0.39,N/A,0.15
2022-08-19,2022-09-02,Nerves and central nervous system,Bell's Palsy/facial paralysis* BCD 1-3,120,37,13,0,0,1,171,0.20,0.15,0.46,N/A,0.20
2022-08-19,2022-09-02,Nerves and central nervous system,Cerebrovascular accident (stroke),142,63,40,0,0,7,252,0.24,0.25,1.42,N/A,0.29
2022-08-19,2022-09-02,Nerves and central nervous system,Transverse myelitis (inflammation of spinal cord),11,5,0,0,0,0,16,0.02,N/A,N/A,N/A,0.02
2022-08-19,2022-09-02,Nerves and central nervous system,Subtotal n (%),273,105,53,0,0,8,439,0.46,0.42,1.88,N/A,0.50
2022-08-19,2022-09-02,Other system,Anaphylaxis*,641,193,28,4,3,1,870,1.08,0.78,1.00,N/A,1.00
2022-08-19,2022-09-02,Other system,COVID-19*,584,63,9,9,0,40,705,0.98,0.25,N/A,N/A,0.81
2022-08-19,2022-09-02,Other system,Multisystem inflammatory syndrome,17,1,0,0,0,1,19,0.03,N/A,N/A,N/A,0.02
2022-08-19,2022-09-02,Other system,Subtotal n (%),1242,257,37,13,3,42,1594,2.09,1.03,1.32,57.16,1.83
2022-08-19,2022-09-02,Pregnancy outcomes,Fetal growth restriction,5,0,0,0,0,0,5,N/A,N/A,N/A,N/A,N/A
2022-08-19,2022-09-02,Pregnancy outcomes,Spontaneous abortion,64,21,1,0,0,0,86,0.11,0.08,N/A,N/A,0.10
2022-08-19,2022-09-02,Pregnancy outcomes,Subtotal n (%),69,21,1,0,0,0,91,0.12,0.08,N/A,N/A,0.10
2022-08-19,2022-09-02,Respiratory system,Acute respiratory distress syndrome,6,4,0,0,0,0,10,N/A,N/A,N/A,N/A,0.01
2022-08-19,2022-09-02,Respiratory system,Subtotal n (%),6,4,0,0,0,0,10,N/A,N/A,N/A,N/A,0.01
2022-08-19,2022-09-02,"Skin and mucous membrane, bone and joints system",Chilblains,21,6,2,0,0,0,29,0.04,N/A,N/A,N/A,0.03
2022-08-19,2022-09-02,"Skin and mucous membrane, bone and joints system",Erythema multiforme (immune skin reaction),30,19,4,1,0,0,54,0.05,0.08,N/A,N/A,0.06
2022-08-19,2022-09-02,"Skin and mucous membrane, bone and joints system",Subtotal n (%),51,25,6,1,0,0,83,0.09,0.10,N/A,N/A,0.10
2022-08-19,2022-09-02,All AESI categories,TOTAL,3385,1285,621,18,4,80,5393,5.70,5.17,22.07,79.15,6.18